Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Isabelle Duroux"'
Autor:
Maria-Bernadette Madel, Julia Halper, Lidia Ibáñez, Lozano Claire, Matthieu Rouleau, Antoine Boutin, Adrien Mahler, Rodolphe Pontier-Bres, Thomas Ciucci, Majlinda Topi, Christophe Hue, Jerome Amiaud, Salvador Iborra, David Sancho, Dominique Heymann, Henri-Jean Garchon, Dorota Czerucka, Florence Apparailly, Isabelle Duroux-Richard, Abdelilah Wakkach, Claudine Blin-Wakkach
Publikováno v:
eLife, Vol 12 (2023)
Bone destruction is a hallmark of chronic inflammation, and bone-resorbing osteoclasts arising under such a condition differ from steady-state ones. However, osteoclast diversity remains poorly explored. Here, we combined transcriptomic profiling, di
Externí odkaz:
https://doaj.org/article/6083ac1d14ed43ab8fc05c983bd5338d
Autor:
Isabelle Duroux-Richard, Anne-Laure Gagez, Elina Alaterre, Rémi Letestu, Olfa Khalifa, Christian Jorgensen, Stéphane Leprêtre, Emmanuelle Tchernonog, Jérôme Moreaux, Guillaume Cartron, Florence Apparailly
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
During many years, chemo-immunotherapy fludarabine-cyclophosphamide-rituximab (FCR) was the gold standard for first line treatment of medically fit patients with symptomatic B-chronic lymphocytic leukemia (CLL). Over the last decade, targeted biother
Externí odkaz:
https://doaj.org/article/1ff8fb046b8b456b860dc1a536915379
Autor:
Cécile Rittore, Déborah Méchin, Elodie Sanchez, Léa Marinèche, Vuthy Ea, Stephan Soler, Marion Vereecke, Aude Mallavialle, Eric Richard, Isabelle Duroux-Richard, Florence Apparailly, Isabelle Touitou, Sylvie Grandemange
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Abstract Binding of tumour necrosis factor α (TNFα) to its receptor (TNFR1) is critical for both survival and death cellular pathways. TNFα/TNFR1 signalling is complex and tightly regulated at different levels to control cell fate decisions. Previ
Externí odkaz:
https://doaj.org/article/a4e7c6e8c75e4d73b0e1b39d5758f67a
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
A subset of microRNA (miRNA) has been shown to play an important role in mitochondrial (mt) functions and are named MitomiR. They are present within or associated with mitochondria. Most of the mitochondrial miRNAs originate from the nucleus, while a
Externí odkaz:
https://doaj.org/article/75fb3a345f5a4b328e761fd89beecb2c
Autor:
Pauline Bade, Fabrizio Simonetti, Stephanie Sans, Patricia Laboudie, Khadija Kissane, Nicolas Chappat, Sophie Lagrange, Florence Apparailly, Christine Roubert, Isabelle Duroux-Richard
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Mycobacterium tuberculosis (Mtb), the etiological agent of tuberculosis, kills 1.5 to 1.7 million people every year. Macrophages are Mtb’s main host cells and their inflammatory response is an essential component of the host defense against Mtb. Ho
Externí odkaz:
https://doaj.org/article/933aae839b0640d6aaca6845fbf0a6b1
Autor:
Yves-Marie Pers, Claire Bony, Isabelle Duroux-Richard, Laurène Bernard, Marie Maumus, Said Assou, Frank Barry, Christian Jorgensen, Danièle Noël
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
ObjectivesMesenchymal stem/stromal cells (MSCs) are widely investigated in regenerative medicine thanks to their immunomodulatory properties. They exert their anti-inflammatory function thanks to the secretion of a number of mediators, including prot
Externí odkaz:
https://doaj.org/article/74bdadb6e40043218592f8f57cad5271
Autor:
Claire Lozano, Valentin Estibals, Gabriel Courties, Hortense Courot, Claudine Blin-Wakkach, Maria-Bernadette Madel, Christophe Hue, Hendrick Mambu Mambueni, Henri-Jean Garchon, Virginie Escriou, Florence Apparailly, Isabelle Duroux-Richard
Publikováno v:
Bone Reports, Vol 13, Iss , Pp 100458- (2020)
Externí odkaz:
https://doaj.org/article/7f1d8863f31e40d1834a1fbd9882a893
Autor:
Maïlys Cren, Nadège Nziza, Aurélia Carbasse, Perrine Mahe, Emilie Dufourcq-Lopez, Marion Delpont, Hugues Chevassus, Mirna Khalil, Thibault Mura, Isabelle Duroux-Richard, Florence Apparailly, Eric Jeziorski, Pascale Louis-Plence
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Despite their distinct etiology, several lines of evidence suggest that innate immunity plays a pivotal role in both juvenile idiopathic arthritis (JIA) and septic arthritis (SA) pathophysiology. Indeed, monocytes and dendritic cells (DC) are involve
Externí odkaz:
https://doaj.org/article/f962719554754742b4de90921afe6e56
Autor:
Maria-Bernadette Madel, Lidia Ibáñez, Thomas Ciucci, Julia Halper, Matthieu Rouleau, Antoine Boutin, Christophe Hue, Isabelle Duroux-Richard, Florence Apparailly, Henri-Jean Garchon, Abdelilah Wakkach, Claudine Blin-Wakkach
Publikováno v:
eLife, Vol 9 (2020)
Bone destruction relies on interactions between bone and immune cells. Bone-resorbing osteoclasts (OCLs) were recently identified as innate immune cells activating T cells toward tolerance or inflammation. Thus, pathological bone destruction not only
Externí odkaz:
https://doaj.org/article/59d193c7baa049dd94c01f3d4668d79b
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Small non-coding microRNAs (miRNAs) have been found to play critical roles in many biological processes by controlling gene expression at the post-transcriptional level. They appear to fine-tune the immune response by targeting key regulatory molecul
Externí odkaz:
https://doaj.org/article/18b5e8b7e1ad4d56be829dd48ccc1dd1