Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Isabelle Dubuc"'
Autor:
Julian Daniel Sunday Willett, Annie Gravel, Isabelle Dubuc, Leslie Gudimard, Ana Claudia dos Santos Pereira Andrade, Émile Lacasse, Paul Fortin, Ju-Ling Liu, Jose Avila Cervantes, Jose Hector Galvez, Haig Hugo Vrej Djambazian, Melissa Zwaig, Anne-Marie Roy, Sally Lee, Shu-Huang Chen, Jiannis Ragoussis, Louis Flamand
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-13 (2024)
Abstract The persistence of SARS-CoV-2 despite the development of vaccines and a degree of herd immunity is partly due to viral evolution reducing vaccine and treatment efficacy. Serial infections of wild-type (WT) SARS-CoV-2 in Balb/c mice yield mou
Externí odkaz:
https://doaj.org/article/7e05d290e45d4f32a383ce6ae1b567f7
Autor:
Jade Gauvin, David N. Huynh, Isabelle Dubuc, Catherine Lê, Rafaela Tugores, Nicolas Flamand, Louis Flamand, William D. Lubell, Huy Ong, Sylvie Marleau
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
The scientific and medical community faced an unprecedented global health hazard that led to nearly 7 million deaths attributable to the rapid spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. In spite of the developme
Externí odkaz:
https://doaj.org/article/d8ca08f8ad2340e48c5400adb8f2cd07
Autor:
Isabelle Dubuc, Julien Prunier, Émile Lacasse, Annie Gravel, Florian Puhm, Isabelle Allaeys, Anne-Sophie Archambault, Leslie Gudimard, Rosaria Villano, Arnaud Droit, Nicolas Flamand, Éric Boilard, Louis Flamand
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Coronavirus disease 19 (COVID-19) is the clinical manifestation of severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2) infection. A hallmark of COVID-19 is a lung inflammation characterized by an abundant leukocyte infiltrate, elevated level
Externí odkaz:
https://doaj.org/article/490d514fb31d4f42af1ccb46ce483309
Autor:
Émile Lacasse, Leslie Gudimard, Isabelle Dubuc, Annie Gravel, Isabelle Allaeys, Éric Boilard, Louis Flamand
Publikováno v:
Viruses, Vol 15, Iss 2, p 334 (2023)
COVID-19 is associated with robust inflammation and partially impaired antiviral responses. The modulation of inflammatory gene expression by SARS-CoV-2 is not completely understood. In this study, we characterized the inflammatory and antiviral resp
Externí odkaz:
https://doaj.org/article/72024b8cbdbb4ae8bd292a8775828f64
Autor:
Élie Besserer-Offroy, Pascal Tétreault, Rebecca L Brouillette, Adeline René, Alexandre Murza, Roberto Fanelli, Karyn Kirby, Alexandre Parent, Isabelle Dubuc, Nicolas Beaudet, Jérôme Côté, Jean-Michel Longpré, Jean Martinez, Florine Cavelier, Philippe Sarret
Publikováno v:
Data in Brief, Vol 31, Iss , Pp 105884- (2020)
Neurotensin (NT) is a tridecapeptide displaying interesting antinociceptive properties through its action on its receptors, NTS1 and NTS2. Neurotensin-like compounds have been shown to exert better antinociceptive properties than morphine at equimola
Externí odkaz:
https://doaj.org/article/7e1f54a7e3e54f5d8d076d1b38926432
Autor:
Anthony J. Saviola, Cosima Zimmermann, Michael P. Mariani, Sylvia A. Signorelli, Diana L. Gerrard, Joseph R. Boyd, Darren J. Wight, Guillaume Morissette, Annie Gravel, Isabelle Dubuc, Louis Flamand, Benedikt B. Kaufer, Seth Frietze
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
Human herpesvirus-6A (HHV-6A) and 6B (HHV-6B) are two closely related betaherpesviruses that are associated with various diseases including seizures and encephalitis. The HHV-6A/B genomes have been shown to be present in an integrated state in the te
Externí odkaz:
https://doaj.org/article/fa0d6b7dc55448a197de80e013354e60
Autor:
Bogdan Galusca, Gaëtan Prévost, Natacha Germain, Isabelle Dubuc, Yiin Ling, Youssef Anouar, Bruno Estour, Nicolas Chartrel
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0122040 (2015)
Anorexia nervosa (AN) presents an adaptive appetite regulating profile including high levels of ghrelin and 26RFa (orexigenic) and low levels of leptin and PYY (anorexigenic). However, this adaptive mechanism is not effective in promoting food intake
Externí odkaz:
https://doaj.org/article/328e8085904144aba835d0b8d614e0fd
Autor:
Julian Daniel Sunday Willett, Annie Gravel, Isabelle Dubuc, Leslie Gudimard, Ana Claudia dos Santos Pereira Andrade, Émile Lacasse, Paul Fortin, Ju-Ling Liu, Jose Avila Cervantes, Jose Hector Galvez, Haig Hugo Vrej Djambazian, Melissa Zwaig, Anne-Marie Roy, Sally Lee, Shu-Huang Chen, Jiannis Ragoussis, Louis Flamand
The persistence of COVID-19 is partly due to viral evolution reducing vaccine and treatment efficacy. Serial infections of Wuhan-like SARS-CoV-2 in Balb/c mice yielded mouse-adapted strains with greater infectivity and mortality. We investigated if p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::39def01c4e7d1876e7ca690a34b45f4e
https://doi.org/10.1101/2023.01.16.523994
https://doi.org/10.1101/2023.01.16.523994
Autor:
Émile Lacasse, Isabelle Dubuc, Leslie Gudimard, Annie Gravel, Isabelle Allaeys, Éric Boilard, Louis Flamand
Since the beginning of the COVID-19 pandemic, enormous efforts were devoted to understanding how SARS-CoV-2 escapes the antiviral response. Yet, modulation of type I interferons (IFNs) by this virus is not completely understood. Using in vitro and in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d113a1ae79ed6e9f47ca60c4b3261b3
https://doi.org/10.1101/2022.06.09.495586
https://doi.org/10.1101/2022.06.09.495586
Autor:
Santa-Mariela Olivera-Ugarte, Marilène Bolduc, Marie-Ève Laliberté-Gagné, Léa-Jeanne Blanchette, Caroline Garneau, Maude Fillion, Pierre Savard, Isabelle Dubuc, Louis Flamand, Omar Farnòs, Xingge Xu, Amine Kamen, Mégan Gilbert, Henintsoa Rabezanahary, Martina Scarrone, Christian Couture, Mariana Baz, Denis Leclerc
Publikováno v:
Nanomedicine : nanotechnology, biology, and medicine. 44
A vaccine candidate to SARS-CoV-2 was constructed by coupling the viral receptor binding domain (RBD) to the surface of the papaya mosaic virus (PapMV) nanoparticle (nano) to generate the RBD-PapMV vaccine. Immunization of mice with the coupled RBD-P