Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Isabelle Correia"'
Autor:
Fabien Le Chevalier, Isabelle Correia, Lucrèce Matheron, Morgan Babin, Mireille Moutiez, Nicolas Canu, Muriel Gondry, Olivier Lequin, Pascal Belin
Publikováno v:
Microbial Cell Factories, Vol 19, Iss 1, Pp 1-16 (2020)
Abstract Background Cyclodipeptide oxidases (CDOs) are enzymes involved in the biosynthesis of 2,5-diketopiperazines, a class of naturally occurring compounds with a large range of pharmaceutical activities. CDOs belong to cyclodipeptide synthase (CD
Externí odkaz:
https://doaj.org/article/f25dc7239b8a4460a3d5f4a96e21e08c
Autor:
Yaochun Xu, Isabelle Correia, Tap Ha-Duong, Nadjib Kihal, Jean-Louis Soulier, Julia Kaffy, Benoît Crousse, Olivier Lequin, Sandrine Ongeri
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 13, Iss 1, Pp 2842-2853 (2017)
Pentapeptides having the sequence R-HN-Ala-Val-X-Val-Leu-OMe, where the central residue X is L-serine, L-threonine, (2S,3R)-L-CF3-threonine and (2S,3S)-L-CF3-threonine were prepared. The capacity of (2S,3S)- and (2S,3R)-CF3-threonine analogues to sta
Externí odkaz:
https://doaj.org/article/53c1aefd96444b4eb73174c4081b5622
Autor:
Zahid Raja, Sonia André, Feten Abbassi, Vincent Humblot, Olivier Lequin, Tahar Bouceba, Isabelle Correia, Sandra Casale, Thierry Foulon, Denis Sereno, Bruno Oury, Ali Ladram
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0174024 (2017)
Antimicrobial peptides (AMPs) are promising drugs to kill resistant pathogens. In contrast to bacteria, protozoan parasites, such as Leishmania, were little studied. Therefore, the antiparasitic mechanism of AMPs is still unclear. In this study, we s
Externí odkaz:
https://doaj.org/article/10601ede856746468b4300472b770abe
Publikováno v:
Organic & Biomolecular Chemistry. 20:8430-8437
Studies on the synthetic methodologies and the structural propensity of peptides containing consecutive aza-amino acids are still in their infancy. Here, details of the synthesis and conformational analysis of tripeptides containing two consecutive a
Autor:
Marion Doladilhe, Vincent Dive, Olivier Lequin, Pierrick Bruyat, Monika Kaminska, Dimitris Georgiadis, Carole Fruchart Gaillard, Mélissa De Souza, Robert Thai, Evelyne Cassar-Lajeunesse, Carole Malgorn, Laurent Devel, Andrzej Galat, Fabrice Beau, Sarah Bregant, Isabelle Correia
Publikováno v:
Angewandte Chemie International Edition
Angewandte Chemie International Edition, 2021, 60 (33), pp.18272-18279. ⟨10.1002/anie.202106117⟩
Angewandte Chemie International Edition, 2021, 60 (33), pp.18272-18279. ⟨10.1002/anie.202106117⟩
International audience; Activity-based probes enable discrimination between the active enzyme and its inactive or inactivated counterparts. Since metalloproteases catalysis is non-covalent, activity-based probes targeting them have been systematicall
Autor:
Héloïse Cahuzac, Antoine Sallustrau, Carole Malgorn, Fabrice Beau, Peggy Barbe, Victor Babin, Steven Dubois, Alberto Palazzolo, Robert Thai, Isabelle Correia, Ki Baek Lee, Sébastien Garcia-Argote, Olivier Lequin, Mathilde Keck, Hervé Nozach, Sophie Feuillastre, Xin Ge, Gregory Pieters, Davide Audisio, Laurent Devel
Publikováno v:
Journal of Medicinal Chemistry
Journal of Medicinal Chemistry, 2022, 65 (9), pp.6953-6968. ⟨10.1021/acs.jmedchem.2c00401⟩
J Med Chem
Journal of Medicinal Chemistry, 2022, 65 (9), pp.6953-6968. ⟨10.1021/acs.jmedchem.2c00401⟩
J Med Chem
International audience; In preclinical models, the development and optimization of protein−drug conjugates require accurate determination of the plasma and tissue profiles of both the protein and its conjugated drug. To this aim, we developed a bio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee0c09f6e879fec0f8c0d7b7f704cad2
https://cea.hal.science/cea-03834302
https://cea.hal.science/cea-03834302
Autor:
Nicolas Canu, Muriel Gondry, Isabelle Correia, Pascal Belin, Robert Thai, Olivier Lequin, Isabelle Jacques, Pavlina Dubois, Steven G. DuBois, Fabien Le Chevalier, Mireille Moutiez
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
Scientific Reports
Scientific Reports, Nature Publishing Group, 2019, 9 (1), pp.9208. ⟨10.1038/s41598-019-45519-y⟩
Scientific Reports, 2019, 9 (1), pp.9208. ⟨10.1038/s41598-019-45519-y⟩
Scientific Reports
Scientific Reports, Nature Publishing Group, 2019, 9 (1), pp.9208. ⟨10.1038/s41598-019-45519-y⟩
Scientific Reports, 2019, 9 (1), pp.9208. ⟨10.1038/s41598-019-45519-y⟩
Prenylated indole diketopiperazine (DKP) alkaloids are important bioactive molecules or their precursors. In the context of synthetic biology, efficient means for their biological production would increase their chemical diversification and the disco
Autor:
Olivier Lequin, Nicolas Canu, Muriel Gondry, Pascal Belin, Isabelle Correia, Mireille Moutiez, Morgan Babin, Lucrèce Matheron, Fabien Le Chevalier
Publikováno v:
Microbial Cell Factories
Microbial Cell Factories, 2020, 19 (1), pp.178. ⟨10.1186/s12934-020-01432-y⟩
Microbial Cell Factories, Vol 19, Iss 1, Pp 1-16 (2020)
Microbial Cell Factories, 2020, 19 (1), pp.178. ⟨10.1186/s12934-020-01432-y⟩
Microbial Cell Factories, Vol 19, Iss 1, Pp 1-16 (2020)
Background Cyclodipeptide oxidases (CDOs) are enzymes involved in the biosynthesis of 2,5-diketopiperazines, a class of naturally occurring compounds with a large range of pharmaceutical activities. CDOs belong to cyclodipeptide synthase (CDPS)-depen
Autor:
Olivier Lequin, Jacopo Lesma, Guillaume Bernadat, Nicolo Tonali, Isabelle Correia, Sandrine Ongeri
Publikováno v:
Organic & Biomolecular Chemistry
Organic & Biomolecular Chemistry, 2020, 18, pp.3452-3458. ⟨10.1039/c9ob02654a⟩
Organic and Biomolecular Chemistry
Organic and Biomolecular Chemistry, Royal Society of Chemistry, 2020, 18, pp.3452-3458. ⟨10.1039/c9ob02654a⟩
Organic & Biomolecular Chemistry, 2020, 18, pp.3452-3458. ⟨10.1039/c9ob02654a⟩
Organic and Biomolecular Chemistry
Organic and Biomolecular Chemistry, Royal Society of Chemistry, 2020, 18, pp.3452-3458. ⟨10.1039/c9ob02654a⟩
International audience; A major current issue in medicinal chemistry is the design of small peptide analogues resistant to proteolysis and able to adopt preferential conformations, while preserving the selectivity and efficiency of natural peptides.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db68278106f86cb769151cb7e01f28d2
https://doi.org/10.1039/c9ob02654a
https://doi.org/10.1039/c9ob02654a
Autor:
Hye-Yeong Kim, Yunpeng Ye, Olivier Lequin, Jae-Joon Jung, Kiran Babu Gona, Vincent Dive, Fabrice Beau, Mahmoud Razavian, Isabelle Correia, Jakub Toczek, Mehran M. Sadeghi, Dimitris Georgiadis, Laurent Devel, Thomas Bordenave
Publikováno v:
Journal of Medicinal Chemistry
Journal of Medicinal Chemistry, American Chemical Society, 2019, 62 (21), pp.9743-9752. ⟨10.1021/acs.jmedchem.9b01186⟩
J Med Chem
Journal of Medicinal Chemistry, 2019, 62 (21), pp.9743-9752. ⟨10.1021/acs.jmedchem.9b01186⟩
Journal of Medicinal Chemistry, American Chemical Society, 2019, 62 (21), pp.9743-9752. ⟨10.1021/acs.jmedchem.9b01186⟩
J Med Chem
Journal of Medicinal Chemistry, 2019, 62 (21), pp.9743-9752. ⟨10.1021/acs.jmedchem.9b01186⟩
Matrix metalloproteinase-12 (MMP-12) is highly upregulated in several inflammatory diseases, including abdominal aortic aneurysm (AAA). Here we report four novel (99m)Tc-labeled radiotracers derived from a highly selective competitive MMP-12 inhibito
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f90c7e2a7e0dabb023a50759aeb27d42
https://hal.archives-ouvertes.fr/hal-02454301
https://hal.archives-ouvertes.fr/hal-02454301