Výsledky vyhledávání - "Isabelle Coiffec"

Akademický článek

An investigation of the endocrine-disruptive effects of bisphenol a in human and rat fetal testes.

Autor: Millissia Ben Maamar, Laurianne Lesné, Christèle Desdoits-Lethimonier, Isabelle Coiffec, Julie Lassurguère, Vincent Lavoué, Yoann Deceuninck, Jean-Philippe Antignac, Bruno Le Bizec, Elisabeth Perdu, Daniel Zalko, Charles Pineau, Cécile Chevrier, Nathalie Dejucq-Rainsford, Séverine Mazaud-Guittot, Bernard Jégou

Publikováno v: PLoS ONE, Vol 10, Iss 2, p e0117226 (2015)

Few studies have been undertaken to assess the possible effects of bisphenol A (BPA) on the reproductive hormone balance in animals or humans with often contradictory results. We investigated possible direct endocrine disruption by BPA of the fetal t

Externí odkaz: https://doaj.org/article/8154709a4c674375ae320b871f8bf1e5

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Dynamics of the transcriptional landscape during human fetal testis and ovary development

Autor: Vincent Lavoué, Millissia Ben Maamar, Frédéric Chalmel, Sabrina Leverrier-Penna, Séverine Mazaud-Guittot, Antoine Rolland, Estelle Lecluze, Bertrand Evrard, Paul Fowler, Bernard Jégou, Panagiotis Filis, Isabelle Coiffec

Publikováno v: Human Reproduction
Human Reproduction, 2020, 35 (5), pp.1099-1119. ⟨10.1093/humrep/deaa041⟩
Human Reproduction, Oxford University Press (OUP), 2020, 35 (5), pp.1099-1119. ⟨10.1093/humrep/deaa041⟩

STUDY QUESTION Which transcriptional program triggers sex differentiation in bipotential gonads and downstream cellular events governing fetal testis and ovary development in humans? SUMMARY ANSWER The characterization of a dynamically regulated prot

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7eff80fcd5565d46c242ace9869424ae
https://doi.org/10.1093/humrep/deaa041

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Endocrine Disruption in Human Fetal Testis Explants by Individual and Combined Exposures to Selected Pharmaceuticals, Pesticides, and Environmental Pollutants

Autor: Isabelle Coiffec, Vincent Lavoué, Andreas Kortenkamp, Bernard Jégou, Séverine Mazaud-Guittot, Laurianne Lesné, Martin Scholze, Nathalie Dejucq-Rainsford, Pierre Gaudriault

Publikováno v: Environmental Health Perspectives
Environmental Health Perspectives, National Institute of Environmental Health Sciences, 2017, 125 (8), pp.087004. ⟨10.1289/EHP1014⟩
Environmental Health Perspectives, 2017, 125 (8), pp.087004. ⟨10.1289/EHP1014⟩

Reproduced with permission from Environmental Health Perspectives Numerous chemicals are capable of disrupting androgen production, but the possibility that they might act together to produce effects greater than those of the most effective component

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::397ba6a211e53913c289bef85a265bb1
https://doi.org/10.1289/ehp1014

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Paracetamol, Aspirin, and Indomethacin Induce Endocrine Disturbances in the Human Fetal Testis Capable of Interfering With Testicular Descent

Autor: Isabelle Coiffec, Séverine Mazaud-Guittot, Patrice Poulain, Vincent Lavoué, David Møbjerg Kristensen, Millissia Ben Maamar, Christèle Desdoits-Lethimonier, Nathalie Dejucq-Rainsford, Cécile Chevrier, Bernard Jégou, Patrick Balaguer, Christophe Nicolas Nicolaz

Publikováno v: Journal of Clinical Endocrinology and Metabolism
Journal of Clinical Endocrinology and Metabolism, Endocrine Society, 2013, 98 (11), pp.E1757-67. ⟨10.1210/jc.2013-2531⟩
Journal of Clinical Endocrinology and Metabolism, 2013, 98 (11), pp.E1757-67. ⟨10.1210/jc.2013-2531⟩

International audience; Context: Masculinization depends on the fetal testis. Exposure of the human fetus during pregnancy to paracetamol or/and to other mild-analgesics is associated with an increased risk of cryptorchidism. Objective:We aimed at de

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b479a24c5290caeebde65c25962f767
https://doi.org/10.1210/jc.2013-2531

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Combined effect of prenatal solvent exposure and GSTT1 or GSTM1 polymorphisms in the risk of birth defects

Autor: Sylvaine Cordier, Isabelle Coiffec, Ronan Garlantézec, Catherine Celebi, Cécile Chevrier

Publikováno v: Birth Defects Research Part A: Clinical and Molecular Teratology
Birth Defects Research Part A: Clinical and Molecular Teratology, Wiley, 2012, 94 (6), pp.481-5. ⟨10.1002/bdra.23018⟩
Birth Defects Research Part A: Clinical and Molecular Teratology, 2012, 94 (6), pp.481-5. ⟨10.1002/bdra.23018⟩

International audience; Exposure to solvents during pregnancy has long been suspected to increase the risk of congenital malformations. Glutathione S-transferases (GSTs) are enzymes essential for the detoxification of various chemicals. Our objective

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38171cd9cbaedf9ecb2760e91e8c8171
https://doi.org/10.1002/bdra.23018

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Expression of the Insulin-Like Peptide 3 (INSL3) Hormone-Receptor (LGR8) System in the Testis1

Autor: Ravinder Anand-Ivell, Isabelle Coiffec-Dorval, Vandana Relan, Martin Fritsch, Ross A. D. Bathgate, Marga Balvers, Richard Ivell

Publikováno v: Biology of Reproduction. 74:945-953

The new peptide hormone insulin-like peptide 3 (INSL3) is a member of the insulin-relaxin family, yet, unlike insulin, it signals through a new G-protein coupled receptor, LGR8, distantly related to the receptors for LH and FSH. INSL3 is produced in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b52663779a8af85a5def4a2ede4f708c
https://doi.org/10.1095/biolreprod.105.048165

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High-Resolution Profiling of Novel Transcribed Regions During Rat Spermatogenesis1

Autor: Bernard Jégou, Aurélie Lardenois, Isabelle Coiffec, Bertrand Evrard, Antoine Rolland, Olivier Collin, Marie-Charlotte Dumargne, Michael Primig, Olivier Sallou, Frédéric Chalmel

Publikováno v: Biology of Reproduction. 91

Mammalian spermatogenesis is a complex and highly orchestrated combination of processes in which male germline proliferation and differentiation result in the production of mature spermatozoa. If recent genome-wide studies have contributed to the in-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::38e5d1f815f5821721ee9d00804a0358
https://doi.org/10.1095/biolreprod.114.118166

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