Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Isabelle Briche"'
Autor:
Carine Brinster, Martin Figeac, Céline Villenet, Bruno Quesnel, Frédéric Leprêtre, Alexia Mopin, Virginie Driss, Isabelle Briche
Publikováno v:
Immunology Letters. 192:27-34
Background In acute myeloid leukaemia (AML)-affected patients, the presence of heterogeneous sub-clones at diagnosis has been shown to be responsible for minimal residual disease and relapses. The role played by the immune system in this leukaemic su
Autor:
Bruno Quesnel, Isabelle Briche, Jerome Kluza, Xavier Thuru, Sylvie Aliegue-Zouitina, Julie Berthe, Hassiba El Bouazzati
Publikováno v:
Cancer Research. 78:384-384
When evolving to a neoplastic state, normal cells acquire many characteristics; indeed, tumor cells follow abnormal metabolic pathways and exhibit the ability to avoid immune destruction, partly by exploiting immune checkpoints. Many of these are cur
Autor:
Anne Loyens, Odile Mercereau-Puijalon, Corinne Biderre, Isabelle Briche, Jean François Dubremetz, Daniel Camus, Abderrahim Achbarou, Carmen Ödberg-Ferragut, Marie Noëlle Fourmaux
Publikováno v:
Molecular and Biochemical Parasitology. 83:201-210
The cDNA encoding the Toxoplasma gondii microneme protein MIC1 and the corresponding gene have been cloned and sequenced. The MIC1 gene contains three introns. The cDNA encodes a 456 amino acid (aa) sequence, with a typical signal sequence and no oth
Autor:
Céline Berthon, Delphine Allorge, Michaela Fontenay, Michel Lhermitte, Isabelle Briche, Benjamin Hennart, Selim Corm, Bruno Quesnel
Publikováno v:
Leukemia research. 37(5)
Tryptophan catabolism, which is mediated by the enzymes indoleamine 2,3-dioxygenase (IDO) and tryptophan 2,3-dioxygenase (TDO), produces kynurenine. Kynurenine itself is converted by downstream enzymes into secondary catabolites. We evaluated the ser
Autor:
Michel Lhermitte, Selim Corm, Bruno Quesnel, Isabelle Briche, Céline Berthon, Michel Imbenotte, Valeria Biggio, Caroline Dupont
Publikováno v:
Leukemia research. 33(3)
The enzyme indoleamine 2,3-dioxygenase (IDO) converts tryptophan to kynurenine, blocking T-cell activation and inducing immunosuppression. In patients with acute myeloid leukemia (AML), the serum kynurenine/tryptophan ratio (Kyn/Trp) was raised, sugg
Autor:
Carine Brinster, Martin Figeac, Isabelle Briche, Frédéric Leprêtre, Virginie Driss, Céline Villenet, Bruno Quesnel
Publikováno v:
Cancer Research. 75:3216-3216
In acute myeloid leukemia (AML), clonal heterogeneity at diagnosis and the presence of minor sub-clones were shown to be responsible for minimal residual disease and relapses in patients. Several studies have proposed that their persistence could be
Autor:
Isabelle Briche, Michel Lhermitte, Michaela Fontenay, Selim Corm, Céline Berthon, Bruno Quesnel
Publikováno v:
Blood. 120:3843-3843
Abstract 3843 Introduction: Tryptophan catabolism, which is mediated by the enzymes indoleamine 2,3-dioxygenase (IDO) and tryptophan 2,3-dioxygenase (TDO), produces kynurenine, which blocks T-cell activation and induces immunosuppression. Kynurenine
Publikováno v:
Biochimie. 67(2)
In non fatal and synchronous P. chabaudi rodent malaria, we observed at the stage of parasitaemia peak, an alteration (50 % decrease) in LCAT activity. This decrease could be related partly to hepatic dysfunction, and mainly to circulating inhibitors