ODIASP: Clinically Contextualized Image Analysis Using the PREDIMED Clinical Data Warehouse, Towards a Better Diagnosis of Sarcopenia

Autor: Katia, Charrière, Pierre-Ephrem, Madiot, Svetlana, Artemova, Pungponhavoan, Tep, Christian, Lenne, Brigitte, Cohard, Alban, Caporossi, Isabelle, Boudry, Juliette, Meyzenc, Gilbert, Ferretti, Ivan, Bricault, Joris, Giai, Jean-Luc, Bosson, Eric, Fontaine, Cécile, Bétry, Alexandre, Moreau-Gaudry

Publikováno v: Studies in health technology and informatics. 290

Big Data and Deep Learning approaches offer new opportunities for medical data analysis. With these technologies, PREDIMED, the clinical data warehouse of Grenoble Alps University Hospital, sets up first clinical studies on retrospective data. In par

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4ae4c96a00c6c1b7e1aed624182ad100
https://pubmed.ncbi.nlm.nih.gov/35673209

Time course of skin features and inflammatory biomarkers after liquid sulfur mustard exposure in SKH-1 hairless mice

Autor: André Peinnequin, Julien Wartelle, Marine Bertoni, Mohamed Batal, Sandy Emorine, Isabelle Boudry, Thierry Douki, Nacera El Bakdouri, Stéphane Mouret, Thomas Poyot, Cécile Cléry-Barraud

Publikováno v: Toxicology Letters
Toxicology Letters, Elsevier, 2015, 232 (1), pp.68-78. ⟨10.1016/j.toxlet.2014.09.022⟩
Toxicology Letters, 2015, 232 (1), pp.68-78. ⟨10.1016/j.toxlet.2014.09.022⟩

International audience; Sulfur mustard (SM) is a strong bifunctional alkylating agent that produces severe tissue injuries characterized by erythema, edema, subepidermal blisters and a delayed inflammatory response after cutaneous exposure. However,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04ec263ce62e0f2a2aea8e676639b7fc
https://doi.org/10.1016/j.toxlet.2014.09.022

Temporal and spatial features of the formation of DNA adducts in sulfur mustard-exposed skin

Autor: Thierry Douki, Marine Bertoni, Izabel Bérard, Sandy Emorine, Mohamed Batal, Stéphane Mouret, Isabelle Boudry, Julien Wartelle, Cécile Cléry-Barraud

Publikováno v: Toxicology and applied pharmacology
Toxicology and applied pharmacology, 2013, 273 (3), pp.644-650
HAL

Sulfur mustard (SM) is a chemical warfare agent that targets skin where it induces large blisters. DNA alkylation is a critical step to explain SM-induced cutaneous symptoms. We determined the kinetics of formation of main SM-DNA adducts and compare

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::073f5f45e80d7c8df75fe29435b97173
https://doi.org/10.1016/j.taap.2013.10.010

A guanine-ethylthioethyl-glutathione adduct as a major DNA lesion in the skin and in organs of mice exposed to sulfur mustard

Autor: Nadège Hamon, Mohamed Batal, Isabelle Boudry, Stéphane Mouret, Thierry Douki, Silvestre Rebelo-Moreira, Pierre-Alain Bayle, Cécile Cléry-Barraud

Publikováno v: Toxicology Letters
Toxicology Letters, Elsevier, 2015, 233 (1), pp.1-7. ⟨10.1016/j.toxlet.2015.01.001⟩
Toxicology Letters, 2015, 233 (1), pp.1-7. ⟨10.1016/j.toxlet.2015.01.001⟩

International audience; Sulfur mustard (SM) is an old chemical warfare but it remains a threat to both militaries and civilians. SM mainly targets skin, eyes and lungs and diffuses to internal organs. At the molecular level, SM is able to damage DNA

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2e08be53994968fd5557217c07dee3e
https://hal.archives-ouvertes.fr/hal-01586121

Relative yields of monomeric and dimeric adducts induced by sulphur mustard in isolated and cellular DNA as determined by HPLC/tandem mass spectrometry

Autor: Thierry Douki, Cécile Cléry-Barraud, Mohamed Batal, Isabelle Boudry, Stéphane Mouret

Publikováno v: Toxicological and Environmental Chemistry
Toxicological and Environmental Chemistry, Taylor & Francis, 2013, 95 (2), pp.260-276
Toxicological and Environmental Chemistry, 2013, 95 (2), pp.260-276
HAL

Sulphur mustard (SM) is known as an efficient vesicating agent as well as a carcinogenic chemical. This warfare agent remains a threat for both civilians and militaries. DNA alkylation is one of the critical molecular pathways at the origin of the sy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6323e025b996d1ef7871fccdc30e9a6b
https://hal.archives-ouvertes.fr/hal-02054526