Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Isabelle Borghini"'
Autor:
Raman Sharma, Hema Sharma, Siôn Jones, Isabelle Borghini-Fuhrer, Gonzalo J. Domingo, Rachel A. Gibson, Katie Rolfe, Lionel Tan, Ioana Gabriela Fiţa, Chao Chen, Panayota Bird, Anup Pingle, Stephan Duparc
Publikováno v:
Malaria Journal, Vol 23, Iss 1, Pp 1-6 (2024)
Abstract A single 300 mg dose of tafenoquine (an 8-aminoquinoline), in combination with a standard 3-day course of chloroquine, is approved in several countries for the radical cure (prevention of relapse) of Plasmodium vivax malaria in patients aged
Externí odkaz:
https://doaj.org/article/8e4d2be46a454fcaaae784e04ad2fa94
Autor:
Michael Ramharter, Abdoulaye A. Djimde, Isabelle Borghini-Fuhrer, Robert Miller, Jangsik Shin, Adam Aspinall, Naomi Richardson, Martina Wibberg, Lawrence Fleckenstein, Sarah Arbe-Barnes, Stephan Duparc
Publikováno v:
Malaria Journal, Vol 23, Iss 1, Pp 1-18 (2024)
Abstract Background Children are particularly at risk of malaria. This analysis consolidates the clinical data for pyronaridine–artesunate (PA) paediatric granules in children from three randomized clinical trials and a real-world study (CANTAM). M
Externí odkaz:
https://doaj.org/article/c0a0c67d6b674912b88c1f867080b596
Autor:
Mirjam Groger, Gaston Tona Lutete, Serge-Brice Assi, Jude D. Bigoga, Nsengi Y. Ntamabyaliro, Sarah Arbe-Barnes, Jangsik Shin, Ayola A. Adegnika, Francine Ntoumi, Peter G. Kremsner, Michael Ramharter, Stephan Duparc, Isabelle Borghini-Fuhrer, Ghyslain Mombo-Ngoma
Publikováno v:
International Journal of Infectious Diseases, Vol 137, Iss , Pp 114-117 (2023)
Global health, particularly in underserved settings can benefit immensely from well-trained community health workers (CHWs) supporting primary healthcare interventions. They can reduce morbidity and mortality of infectious diseases like malaria. Dise
Externí odkaz:
https://doaj.org/article/bccdc2d935c8459daa3b85ad7bc4a26a
Autor:
Andrea Kuemmerle, Denis Gossen, Annick Janin, Andrew Stokes, Nada Abla, Maja Szramowska, Ulrike Lorch, Myriam El Gaaloul, Isabelle Borghini‐Fuhrer, Stephan Chalon
Publikováno v:
Clinical and Translational Science, Vol 17, Iss 4, Pp n/a-n/a (2024)
Abstract Drug resistance to sulfadoxine‐pyrimethamine and amodiaquine threatens the efficacy of malaria chemoprevention interventions in children and pregnant women. Combining pyronaridine (PYR) and piperaquine (PQP), both components of approved an
Externí odkaz:
https://doaj.org/article/d70d40b00e2d4329bab91bab1adbd6b8
Autor:
Gaston Tona Lutete, Ghyslain Mombo-Ngoma, Serge-Brice Assi, Jude D Bigoga, Felix Koukouikila-Koussounda, Nsengi Y Ntamabyaliro, Francine Ntoumi, Selidji T Agnandji, Mirjam Groger, Jangsik Shin, Isabelle Borghini-Fuhrer, Sarah Arbe-Barnes, Stephen J Allen, Peter G Kremsner, Robert Miller, Stephan Duparc, Michael Ramharter, CANTAM study group
Publikováno v:
PLoS Medicine, Vol 18, Iss 6, p e1003669 (2021)
BackgroundIn Phase II/III randomized controlled clinical trials for the treatment of acute uncomplicated malaria, pyronaridine-artesunate demonstrated high efficacy and a safety profile consistent with that of comparators, except that asymptomatic, m
Externí odkaz:
https://doaj.org/article/60c05cb80685497f9aa0118680647324
Autor:
Robert J. Commons, Julie A. Simpson, Kamala Thriemer, Cindy S. Chu, Nicholas M. Douglas, Tesfay Abreha, Sisay G. Alemu, Arletta Añez, Nicholas M. Anstey, Abraham Aseffa, Ashenafi Assefa, Ghulam R. Awab, J. Kevin Baird, Bridget E. Barber, Isabelle Borghini-Fuhrer, Umberto D’Alessandro, Prabin Dahal, André Daher, Peter J. de Vries, Annette Erhart, Margarete S. M. Gomes, Matthew J. Grigg, Jimee Hwang, Piet A. Kager, Tsige Ketema, Wasif A. Khan, Marcus V. G. Lacerda, Toby Leslie, Benedikt Ley, Kartini Lidia, Wuelton M. Monteiro, Dhelio B. Pereira, Giao T. Phan, Aung P. Phyo, Mark Rowland, Kavitha Saravu, Carol H. Sibley, André M. Siqueira, Kasia Stepniewska, Walter R. J. Taylor, Guy Thwaites, Binh Q. Tran, Tran T. Hien, José Luiz F. Vieira, Sonam Wangchuk, James Watson, Timothy William, Charles J. Woodrow, Francois Nosten, Philippe J. Guerin, Nicholas J. White, Ric N. Price
Publikováno v:
BMC Medicine, Vol 17, Iss 1, Pp 1-13 (2019)
Abstract Background Malaria causes a reduction in haemoglobin that is compounded by primaquine, particularly in patients with glucose-6-phosphate dehydrogenase (G6PD) deficiency. The aim of this study was to determine the relative contributions to re
Externí odkaz:
https://doaj.org/article/0c7b7a122f5a4e65af16c64245f046e3
Autor:
Yi Poravuth, Duong Socheat, Ronnatrai Rueangweerayut, Chirapong Uthaisin, Aung Pyae Phyo, Neena Valecha, B H Krishnamoorthy Rao, Emiliana Tjitra, Asep Purnama, Isabelle Borghini-Fuhrer, Stephan Duparc, Chang-Sik Shin, Lawrence Fleckenstein
Publikováno v:
PLoS ONE, Vol 6, Iss 1, p e14501 (2011)
New antimalarials are needed for P. vivax and P. falciparum malaria. This study compared the efficacy and safety of pyronaridine-artesunate with that of chloroquine for the treatment of uncomplicated P. vivax malaria.This phase III randomized, double
Externí odkaz:
https://doaj.org/article/7330ac29fab5473284fb972beb6f0618
Autor:
Myriam Drysdale, Lionel Tan, Ana Martin, Isabelle Borghini Fuhrer, Stephan Duparc, Hema Sharma
Publikováno v:
Infectious Diseases and Therapy. 12:33-51
There has been progress towards decreasing malaria prevalence globally; however, Plasmodium vivax has been less responsive to elimination efforts compared with Plasmodium falciparum. P. vivax malaria remains a serious public health concern in regions
Autor:
Mirjam Groger, Gaston Tona Lutete, Ghyslain Mombo-Ngoma, Nsengi Y Ntamabyaliro, Gauthier Kahunu Mesia, Trésor Bodjick Muena Mujobu, Lia Betty Dimessa Mbadinga, Rella Zoleko Manego, Diane Egger-Adam, Isabelle Borghini-Fuhrer, Jangsik Shin, Robert Miller, Sarah Arbe-Barnes, Stephan Duparc, Michael Ramharter
Publikováno v:
The Lancet Microbe. 3:e598-e605
High-quality evidence for the therapeutic efficacy and effectiveness of antimalarials for infections caused by Plasmodium malariae, Plasmodium ovale spp, and mixed-Plasmodium infections is scarce. In this study, we aimed to analyse the efficacy of py
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