Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Isabelle Barde"'
Autor:
Benjamin Rauwel, Suk Min Jang, Marco Cassano, Adamandia Kapopoulou, Isabelle Barde, Didier Trono
Publikováno v:
eLife, Vol 4 (2015)
Human cytomegalovirus (HCMV) is a highly prevalent pathogen that induces life-long infections notably through the establishment of latency in hematopoietic stem cells (HSC). Bouts of reactivation are normally controlled by the immune system, but can
Externí odkaz:
https://doaj.org/article/9c6d029a22c640eaa737dfe499233be6
Autor:
Daniel Robyr, Marc Friedli, Corinne Gehrig, Mélanie Arcangeli, Marilyn Marin, Michel Guipponi, Laurent Farinelli, Isabelle Barde, Sonia Verp, Didier Trono, Stylianos E Antonarakis
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e17634 (2011)
Comparative analyses of various mammalian genomes have identified numerous conserved non-coding (CNC) DNA elements that display striking conservation among species, suggesting that they have maintained specific functions throughout evolution. CNC fun
Externí odkaz:
https://doaj.org/article/2f84cd324c99471d91badba72982527e
Autor:
Marc Friedli, Isabelle Barde, Mélanie Arcangeli, Sonia Verp, Alexandra Quazzola, Jozsef Zakany, Nathalie Lin-Marq, Daniel Robyr, Catia Attanasio, François Spitz, Denis Duboule, Didier Trono, Stylianos E Antonarakis
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e15741 (2010)
Finding sequences that control expression of genes is central to understanding genome function. Previous studies have used evolutionary conservation as an indicator of regulatory potential. Here, we present a method for the unbiased in vivo screen of
Externí odkaz:
https://doaj.org/article/d4dead86d0a8437c9a8deaede79cae00
Autor:
Andrea Corsinotti, Isabelle Barde, Adamandia Kapopoulou, Benjamin Rauwel, Julien Marquis, Sandra Offner, Didier Trono, Jiri Vanicek, Elisa Laurenti, Sonia Verp, Ray Marcel Marin-Florez
Publikováno v:
médecine/sciences. 30:12-15
Erythropoiesis releases about one hundred billion new red cells every day from the human adult bone marrow. This process is initiated by the differentiation of hematopoietic stem cells (HSC) into the earliest erythroid progenitor identified ex vivo,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f1f88d7905c49a30889db734b0fb9d8
https://doi.org/10.1051/medsci/20143001003
https://doi.org/10.1051/medsci/20143001003
Autor:
Didier Trono, Sandra Offner, Karolina Bojkowska, Isabelle Barde, Sonia Verp, Christian Heinis, Francesca R. Santoni de Sio, Kai Johnsson
Publikováno v:
Chemistry & biology
SummaryProtein turnover critically influences many biological functions, yet methods have been lacking to assess this parameter in vivo. Here, we demonstrate how chemical labeling of SNAP-tag fusion proteins can be exploited to measure the half-life
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0210aa62bad2de191e5e77d4d97c4e52
https://doi.org/10.1016/j.chembiol.2011.03.014
https://doi.org/10.1016/j.chembiol.2011.03.014
Autor:
Sonia Verp, Didier Trono, Maciej Wiznerowicz, Elisa Laurenti, Isabelle Barde, A. Viornery, Sandra Offner, Anne Galy, Andreas Trumpp
Publikováno v:
Gene Ther
Gene Ther, 2011, 18 (11), pp.1087-97. ⟨10.1038/gt.2011.65⟩
Gene therapy
Gene Therapy
Gene Therapy, 2011, 18 (11), pp.1087-1097. ⟨10.1038/gt.2011.65⟩
Gene Ther, 2011, 18 (11), pp.1087-97. ⟨10.1038/gt.2011.65⟩
Gene therapy
Gene Therapy
Gene Therapy, 2011, 18 (11), pp.1087-1097. ⟨10.1038/gt.2011.65⟩
International audience; Insertional mutagenesis represents a serious adverse effect of gene therapy with integrating vectors. However, although uncontrolled activation of growth-promoting genes in stem cells can predictably lead to oncological proces
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25cd5d9386435a238d60fb8a2a602564
https://doi.org/10.1038/gt.2011.65
https://doi.org/10.1038/gt.2011.65
Autor:
Elisa Laurenti, Andreas Trumpp, Patrick Aebischer, Chris Towne, Didier Trono, Isabelle Barde, Viviane Padrun, Anna C. Groner, Sonia Verp
Publikováno v:
Journal of Virology. 83:5574-5580
KAP1 is an essential cofactor of KRAB zinc finger proteins, a family of vertebrate-specific epigenetic repressors of largely unknown functions encoded in the hundreds by the mouse and human genomes. So far, KRAB/KAP1-mediated gene regulation has been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5306c88c3fc0f9a15f505b06fdb58bf0
https://doi.org/10.1128/jvi.00001-09
https://doi.org/10.1128/jvi.00001-09
Autor:
Judith Trüb, Sonia Verp, Rachel Nlend Nlend, Isabelle Barde, Kathrin Meyer, Didier Trono, Daniel Schümperli, Marc-David Ruepp, Julien Marquis, Hans Imboden
Publikováno v:
HUMAN MOLECULAR GENETICS
Meyer, Kathrin; Marquis, Julien; Trüb, Judith; Nlend Nlend, Rachel; Verp, Sonia; Ruepp, Marc-David; Imboden, Hans; Barde, Isabelle; Trono, Didier; Schümperli, Daniel (2009). Rescue of a severe mouse model for spinal muscular atrophy by U7 snRNA-mediated splicing modulation. Human molecular genetics, 18(3), pp. 546-555. Oxford: Oxford University Press 10.1093/hmg/ddn382
Meyer, Kathrin; Marquis, Julien; Trüb, Judith; Nlend Nlend, Rachel; Verp, Sonia; Ruepp, Marc-David; Imboden, Hans; Barde, Isabelle; Trono, Didier; Schümperli, Daniel (2009). Rescue of a severe mouse model for spinal muscular atrophy by U7 snRNA-mediated splicing modulation. Human molecular genetics, 18(3), pp. 546-555. Oxford: Oxford University Press 10.1093/hmg/ddn382
In spinal muscular atrophy (SMA), the leading genetic cause of early childhood death, the survival motor neuron 1 gene (SMN1) is deleted or inactivated. The nearly identical SMN2 gene has a silent mutation that impairs the utilization of exon 7 and t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef0cb110afcc1a35e3ef091be23fb9f9
http://hmg.oxfordjournals.org/content/18/3/546.long
http://hmg.oxfordjournals.org/content/18/3/546.long
Publikováno v:
Current protocols in mouse biology. 1(1)
The genetic manipulation of rodents through the generation of fully transgenic animals or via the modification of selective cells or organs is a procedure of paramount importance for biomedical research, either to address fundamental questions or to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::faa0a51f9a75370b84ed30381554d046
https://pubmed.ncbi.nlm.nih.gov/26068991
https://pubmed.ncbi.nlm.nih.gov/26068991
