Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Isabelle Tranchant"'
Autor:
Jean Herscovici, Nathalie Mignet, Michel Bessodes, Jeanne Leblond, Isabelle Tranchant, Daniel Scherman, Marie Breton
Publikováno v:
Pharmaceuticals, Vol 4, Iss 10, Pp 1381-1399 (2011)
Non-viral gene therapy requires innovative strategies to achieve higher transfection efficacy. A few years ago, our group proposed bioinspired lipids whoseinteraction with DNA was not based on ionic interactions, but on hydrogen bonds. We thusdevelop
Externí odkaz:
https://doaj.org/article/e8209e6c0724456d87c0795b71e0e728
Autor:
Isabelle Tranchant, Ngee Han Lim, Marc Nazaré, María J. Vicent, Heike Wieland, Oliver Plettenburg, Otmar Kingler, Aroa Duro-Castano, Fabrice Beau, Vincent Dive, Mehdi Amoura, Hideaki Nagase, Matthias Herrmann
Publikováno v:
ADVANCED FUNCTIONAL MATERIALS
r-CIPF. Repositorio Institucional Producción Científica del Centro de Investigación Principe Felipe (CIPF)
Universitat Oberta de Catalunya (UOC)
r-CIPF: Repositorio Institucional Producción Científica del Centro de Investigación Principe Felipe (CIPF)
Centro de Investigación Principe Felipe (CIPF)
Adv. Func. Mat. 28:1802738 (2018)
r-CIPF. Repositorio Institucional Producción Científica del Centro de Investigación Principe Felipe (CIPF)
Universitat Oberta de Catalunya (UOC)
r-CIPF: Repositorio Institucional Producción Científica del Centro de Investigación Principe Felipe (CIPF)
Centro de Investigación Principe Felipe (CIPF)
Adv. Func. Mat. 28:1802738 (2018)
Imaging early molecular changes in osteoarthritic (OA) joints is instrumental for the development of disease-modifying drugs. To this end, a fluorescent resonance energy transfer-based peptide probe that is cleavable by matrix metalloproteinase 13 (M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83edd45dc6381fd8a01389d263039522
https://fundanet.cipf.es/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=1175
https://fundanet.cipf.es/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=1175
Autor:
Laura Vera, Enrico A. Stura, Vincent Dive, Mehdi Amoura, Evelyne Cassar, Bertrand Czarny, Fabrice Beau, Isabelle Tranchant
Publikováno v:
Chemistry & Biology; Vol 21
SummaryMatrix metalloproteinases (MMPs) are a large family of zinc-dependent endoproteases that catalyze cleavage of extracellular matrix and nonmatrix proteins. MMPs play a role in tissue remodeling, and their uncontrolled activity is associated wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::492811531af20906f5f129dc7a76916b
Autor:
Petra J. Cameron, Alethea B. Tabor, Christopher J. Slevin, Sandra Maplin, M.M. Gani, Isabelle Tranchant, A. Toby A. Jenkins, Kris Zak, David E. Williams, Helen C. Hailes, Margarida M. L. M. Vareiro
Publikováno v:
Analytical Biochemistry. 377:243-250
The development of a single-step, separation-free method for measurement of low concentrations of fatty acid using a surface plasmon resonance-enhanced fluorescence competition assay with a surface-bound antibody is described. The assay behavior was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0eede9051612637b830a749336f410c9
https://doi.org/10.1016/j.ab.2008.03.033
https://doi.org/10.1016/j.ab.2008.03.033
Publikováno v:
Theoretical Chemistry Accounts. 120:507-513
A new neutral gene vector, based on a lipopolythiourea N-(2-(3-[2-(2-(3-[2-(3-methyl-thioueido)-ethyl] -thioureido)-ethylamino)-ethyl]-thioureido)-ethyl)- N′, N′- ditetradecyl-succinamide (DTTU) has recently been synthetized but its behavior is d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ceaaf4230188ee6a01921ad89a5e152e
https://doi.org/10.1007/s00214-008-0426-7
https://doi.org/10.1007/s00214-008-0426-7
Autor:
Isabelle, Tranchant, Anne-Cécile, Hervé, Stephen, Carlisle, Phillip, Lowe, Christopher J, Slevin, Camilla, Forssten, John, Dilleen, Rajiv, Bhalla, David E, Williams, Alethea B, Tabor, Helen C, Hailes
Publikováno v:
Bioconjugate Chemistry. 17:1256-1264
A series of ferrocenyl conjugates to fatty acids have been designed and synthesized to establish the key properties required for use in biomolecular binding studies. Amperometric detection of the ferrocene conjugates was sought in the region of 0.3 V
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a2832421926bb64b21259c83a5af30b
https://doi.org/10.1021/bc060038m
https://doi.org/10.1021/bc060038m
Autor:
Gerardo Byk, Jean Herscovici, Marie Carrière, Virginie Escriou, Daniel Scherman, Isabelle Tranchant, Pierre-Antoine Niore, Nathalie Mignet
Publikováno v:
Journal of Liposome Research. 12:95-106
The rationale design aimed at the enhancement of cationic lipid mediated gene transfer is discussed. These improvements are based on the straight evaluation of the structure-activity relationship and on the introduction of new structures. Much attent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d39086d333c9e72b591f75bc50bf6276
https://doi.org/10.1081/lpr-120004781
https://doi.org/10.1081/lpr-120004781
Publikováno v:
Synlett. 2000:1577-1580
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::007f77e773f97c8ca5b8e059bbfcbf94
https://doi.org/10.1055/s-2000-7910
https://doi.org/10.1055/s-2000-7910
Autor:
Michel Bessodes, Isabelle Tranchant, Daniel Scherman, Nathalie Mignet, Marie Breton, Jean Herscovici, Jeanne Leblond
Publikováno v:
Pharmaceuticals
Pharmaceuticals, MDPI, 2011, 4 (10), pp.1381-1399. ⟨10.3390/ph4101381⟩
Pharmaceuticals, 2011, 4 (10), pp.1381-1399. ⟨10.3390/ph4101381⟩
Pharmaceuticals, Vol 4, Iss 10, Pp 1381-1399 (2011)
Pharmaceuticals, MDPI, 2011, 4 (10), pp.1381-1399. ⟨10.3390/ph4101381⟩
Pharmaceuticals, 2011, 4 (10), pp.1381-1399. ⟨10.3390/ph4101381⟩
Pharmaceuticals, Vol 4, Iss 10, Pp 1381-1399 (2011)
International audience; Non-viral gene therapy requires innovative strategies to achieve higher transfection efficacy. A few years ago, our group proposed bioinspired lipids whose interaction with DNA was not based on ionic interactions, but on hydro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c47005be77c9069cae067aaadfb2054e
https://hal.archives-ouvertes.fr/hal-02512516/document
https://hal.archives-ouvertes.fr/hal-02512516/document
Autor:
Florence Meyer-Losic, Fabien Ribes, Valérie Arranz, Jean-Sébastien Fruchart, Imane Zoubaa, Vincent Dubois, Céline Nicolazzi, Jonathan Kearsey, Denis Ravel, Matthieu Michel, Catherine de Coupade, Matthieu Boukaissi, Anne-Sophie Chéné, Jérôme Quinonero, Isabelle Tranchant
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 14(7)
Purpose: Irinotecan is a prodrug converted to the active cytotoxic molecule SN38 predominantly by the action of liver carboxylesterases. The efficacy of irinotecan is limited by this hepatic activation that results in a low conversion rate, high inte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::651fa279cf60e8b026ed0e8a0234f237
https://pubmed.ncbi.nlm.nih.gov/18381956
https://pubmed.ncbi.nlm.nih.gov/18381956