Chronic Internal Exposure to Low Dose 137Cs Induces Positive Impact on the Stability of Atherosclerotic Plaques by Reducing Inflammation in ApoE-/- Mice.

Autor: Clélia Le Gallic, Yohann Phalente, Line Manens, Isabelle Dublineau, Marc Benderitter, Yann Gueguen, Stephanie Lehoux, Teni G Ebrahimian

Publikováno v: PLoS ONE, Vol 10, Iss 6, p e0128539 (2015)

After Chernobyl and Fukushima Daï Chi, two major nuclear accidents, large amounts of radionuclides were released in the environment, mostly caesium 137 (137Cs). Populations living in contaminated territories are chronically exposed to radionuclides

Externí odkaz: https://doaj.org/article/c5aaaba2a79f4fba8d867e05bb7e199e

In vivoanimal studies help achieve international consensus on standards and guidelines for health risk estimates for chronic exposure to low levels of tritium in drinking water

Autor: Julie Leblanc, Christelle Durand, Karine Tack, Marc Benderitter, Sandrine Roch-Lefèvre, Audrey Legendre, Laurence Roy, Philippe Lestaevel, Eric Gregoire, Nicholas D. Priest, Chrystelle Ibanez, Isabelle Dublineau, Teni Ebrahimian, Yann Gueguen, Laura A Bannister, Jean-René Jourdain, Heather Wyatt, Stéphane Grison, Dmitry Klokov

Publikováno v: Environmental and Molecular Mutagenesis. 59:586-594

Existing and future nuclear fusion technologies involve the production and use of large quantities of tritium, a highly volatile, but low toxicity beta-emitting isotope of hydrogen. Tritium has received international attention because of public and s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d0149840e7efad6bafb6f214d4e889bb
https://doi.org/10.1002/em.22200

Effects of repeated potassium iodide administration on genes involved in synthesis and secretion of thyroid hormone in adult male rat

Autor: Jean-René Jourdain, Teni Ebrahimian, Guillaume Phan, David Suhard, Karine Tack, Annick Pech, Maâmar Souidi, Marc Benderitter, Stéphane Grison, Line Manens, Isabelle Dublineau, Dalila Lebsir, Philippe Lestaevel

Publikováno v: Molecular and Cellular Endocrinology
Molecular and Cellular Endocrinology, Elsevier, 2018, 474, pp.119-126. ⟨10.1016/j.mce.2018.02.017⟩

Background A single dose of potassium iodide (KI) is recommended to reduce the risk of thyroid cancer during nuclear accidents. However in case of prolonged radioiodine exposure, more than one dose of KI may be necessary. This work aims to evaluate t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88c05653286c1d151f3af323169a442a
https://pubmed.ncbi.nlm.nih.gov/29496566

Cerebral cortex and hippocampus respond differently after post-natal exposure to uranium

Autor: Olivia Delissen, Isabelle Dublineau, Philippe Voisin, Philippe Lestaevel, Claire-Marie Vacher, Mohammed Taouis, Helene Bensoussan, B. Dhieux

Publikováno v: Journal of Toxicological Sciences 5 (38), 803-811. (2013)
The Journal of Toxicological Sciences
The Journal of Toxicological Sciences, Japanese Society of Toxicology, 2013, 38 (5), pp.803-811
The Journal of Toxicological Sciences, Japanese Society of Toxicology, 2012, 38 (5), pp.803-11. ⟨10.2131/jts.38.803⟩

International audience; The central nervous system (CNS) is known to be sensitive to pollutants during its development. Uranium (U) is a heavy metal that occurs naturally in the environment as a component of the earth's crust, and populations may the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4031d678c8c34aa7777349ed4f144347
https://doi.org/10.2131/jts.38.803

Metabolomics reveals dose effects of low-dose chronic exposure to uranium in rats: identification of candidate biomarkers in urine samples

Autor: Matthieu Maillot, Isabelle Dublineau, Gaëlle Favé, Eric Blanchardon, Line Manens, Maâmar Souidi, Jean-Charles Martin, Olivia Delissen, Jocelyne Aigueperse, Stéphane Grison, Sandra Bohand

Publikováno v: Metabolomics
Metabolomics, Springer Verlag, 2016, 12 (10), ⟨10.1007/s11306-016-1092-8⟩
Metabolomics, 2016, 12 (10), pp.1-16. ⟨10.1007/s11306-016-1092-8⟩
Metabolomics, Springer Verlag, 2016, 12 (10), pp.1-16. ⟨10.1007/s11306-016-1092-8⟩
Metabolomics 10 (12), 1-16. (2016)

Introduction Data are sparse about the potential health risks of chronic low-dose contamination of humans by uranium (natural or anthropogenic) in drinking water. Previous studies report some molecular imbalances but no clinical signs due to uranium

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32758cc7ccd76fab772832166a703c92
https://hal.archives-ouvertes.fr/hal-01479042