Zobrazeno 1 - 10
of 191
pro vyhledávání: '"Isabelle, Soubeyran"'
Autor:
Arnaud Bayle, Laila Belcaid, Sophie Cousin, Kilian Trin, Melissa Alame, Etienne Rouleau, Isabelle Soubeyran, Ludovic Lacroix, Laura Blouin, Damien Vasseur, Amandine Crombe, Simone Mathoulin-Pelissier, Jean-Charles Soria, Carine Bellera, Antoine Italiano
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-5 (2024)
Abstract Selecting patients for phase I cancer trials is crucial to ensure a sufficient life expectancy. Frail patients, better suited for palliative care, should not be exposed to new drugs with minimal benefit. Enrolling patients at high risk of ea
Externí odkaz:
https://doaj.org/article/d05aae3b04e145588413b39998d26d59
Autor:
Sophie Cousin, Jean-Philippe Guégan, Kohei Shitara, Lola Jade Palmieri, Jean Philippe Metges, Simon Pernot, Shota Fukuoka, Shohei Koyama, Hiroyoshi Nishikawa, Carine A. Bellera, Antoine Adenis, Carlos A. Gomez-Roca, Philippe Alexandre Cassier, Antoine Hollebecque, Coralie Cantarel, Michèle Kind, Isabelle Soubeyran, Lucile Vanhersecke, Alban Bessede, Antoine Italiano
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-11 (2024)
Abstract Anti-angiogenic agents elicit considerable immune modulatory effects within the tumor microenvironment, underscoring the rationale for synergistic clinical development of VEGF and immune checkpoint inhibitors in advanced gastric cancer (AGC)
Externí odkaz:
https://doaj.org/article/092395fd8b914e7cbe0ceb717ec9a6b5
Autor:
Marie-Julie Nokin, Alessia Mira, Enrico Patrucco, Biagio Ricciuti, Sophie Cousin, Isabelle Soubeyran, Sonia San José, Serena Peirone, Livia Caizzi, Sandra Vietti Michelina, Aurelien Bourdon, Xinan Wang, Daniel Alvarez-Villanueva, María Martínez-Iniesta, August Vidal, Telmo Rodrigues, Carmen García-Macías, Mark M. Awad, Ernest Nadal, Alberto Villanueva, Antoine Italiano, Matteo Cereda, David Santamaría, Chiara Ambrogio
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Selective KRASG12C inhibitors have been developed to covalently lock the oncogene in the inactive GDP-bound state. Two of these molecules, sotorasib and adagrasib, are approved for the treatment of adult patients with KRASG12C-mutated previo
Externí odkaz:
https://doaj.org/article/720b0c9c9a024f38961f97cf298e776d
Autor:
Arnaud Bayle, Laila Belcaid, Lola-Jade Palmieri, Diego Teysonneau, Sophie Cousin, Mariella Spalato-Ceruso, Mihaela Aldea, Damien Vasseur, Melissa Alame, Laura Blouin, Isabelle Soubeyran, Claudio Nicotra, Maud Ngocamus, Antoine Hollebecque, Yohann Loriot, Benjamin Besse, Ludovic Lacroix, Etienne Rouleau, Fabrice Barlesi, Fabrice Andre, Antoine Italiano
Publikováno v:
Molecular Cancer, Vol 22, Iss 1, Pp 1-7 (2023)
Abstract Background Despite the effectiveness of the various targeted therapies currently approved for solid tumors, acquired resistance remains a persistent problem that limits the ultimate effectiveness of these treatments. Polyclonal resistance to
Externí odkaz:
https://doaj.org/article/52cbb438c71741d8bfa5d463aa3de784
Autor:
Antoine Italiano, Derek Dinart, Isabelle Soubeyran, Carine Bellera, Hélène Espérou, Christelle Delmas, Noémie Mercier, Sabrina Albert, Ludivine Poignie, Anne Boland, Aurélien Bourdon, Damien Geneste, Quentin Cavaille, Yec’han Laizet, Emmanuel Khalifa, Céline Auzanneau, Barbara Squiban, Nathalène Truffaux, Robert Olaso, Zuzana Gerber, Cédrick Wallet, Antoine Bénard, Jean-Yves Blay, Pierre Laurent-Puig, Jean-François Deleuze, Carlo Lucchesi, Simone Mathoulin-Pelissier, the MULTISARC study group
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-10 (2021)
Abstract Background Soft-tissue sarcomas (STS) represent a heterogeneous group of rare tumors including more than 70 different histological subtypes. High throughput molecular analysis (next generation sequencing exome [NGS]) is a unique opportunity
Externí odkaz:
https://doaj.org/article/a537e8b223744e2f9d8f9b6743f5ae55
Autor:
Diego Teyssonneau, Henri Margot, Mathilde Cabart, Mylène Anonnay, Paul Sargos, Nam-Son Vuong, Isabelle Soubeyran, Nicolas Sevenet, Guilhem Roubaud
Publikováno v:
Journal of Hematology & Oncology, Vol 14, Iss 1, Pp 1-19 (2021)
Abstract Despite survival improvements achieved over the last two decades, prostate cancer remains lethal at the metastatic castration-resistant stage (mCRPC) and new therapeutic approaches are needed. Germinal and/or somatic alterations of DNA-damag
Externí odkaz:
https://doaj.org/article/a59f9df956e7452d9f9fdade0d7452fd
Publikováno v:
Bulletin du Cancer. 110:560-569
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df13b88e59d42f37f72a49e33bf1c305
https://doi.org/10.1016/j.bulcan.2022.08.005
https://doi.org/10.1016/j.bulcan.2022.08.005
Autor:
Catherine Ouk, Lilian Roland, Nathalie Gachard, Stéphanie Poulain, Christelle Oblet, David Rizzo, Alexis Saintamand, Quentin Lemasson, Claire Carrion, Morgane Thomas, Karl Balabanian, Marion Espéli, Marie Parrens, Isabelle Soubeyran, Mélanie Boulin, Nathalie Faumont, Jean Feuillard, Christelle Vincent-Fabert
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Activating mutations of MYD88 (MYD88L265P being the far most frequent) are found in most cases of Waldenström macroglobulinemia (WM) as well as in various aggressive B-cell lymphoma entities with features of plasma cell (PC) differentiation, such as
Externí odkaz:
https://doaj.org/article/6ae2c3b7bfc345f6b7a93a374d068805
Autor:
Simone Mathoulin-Pélissier, Antoine Italiano, Anne Boland, Jean-François Deleuze, Helene Blons, Pierre Laurent-Puig, Carine Bellera, Céline Auzanneau, Delphine Bacq, Marlène Boucheix, Aurélien Bourdon, Emmanuelle Chollet, Christine Chomienne, Christelle Delmas, Derek Dinart, Hélène Espérou, Flore Geillon, Damien Geneste, Delphine Jean, Emmanuel Khalifa, Yec'han Laizet, Franck Lethimonnier, Claire Lévy-Marchal, Carlo Lucchesi, Carine Malle, Pierre Mancini, Vincent Meyer, Palomares Marie-Ange, Géraldine Perkins, Sabrina Sellan-Albert, Isabelle Soubeyran, Cédric Wallet
Publikováno v:
ESMO Open, Vol 5, Iss 4 (2020)
Background Whole exome sequencing and RNA sequencing (WES/RNASeq) should now be implemented in the clinical practice in order to increase access to optimal care for cancer patients. Providing results to Tumour Boards in a relevant time frame—that i
Externí odkaz:
https://doaj.org/article/a478a16ea5ed4bfc9882ed3441d03fae
Autor:
Fabrice Andre, Thomas Filleron, Maud Kamal, Fernanda Mosele, Monica Arnedos, Florence Dalenc, Marie-Paule Sablin, Mario Campone, Hervé Bonnefoi, Claudia Lefeuvre-Plesse, William Jacot, Florence Coussy, Jean-Marc Ferrero, George Emile, Marie-Ange Mouret-Reynier, Jean-Christophe Thery, Nicolas Isambert, Alice Mege, Philippe Barthelemy, Benoit You, Nawale Hajjaji, Ludovic Lacroix, Etienne Rouleau, Alicia Tran-Dien, Sandrine Boyault, Valery Attignon, Pierre Gestraud, Nicolas Servant, Christophe Le Tourneau, Linda Larbi Cherif, Isabelle Soubeyran, Filippo Montemurro, Alain Morel, Amelie Lusque, Marta Jimenez, Alexandra Jacquet, Anthony Gonçalves, Thomas Bachelot, Ivan Bieche
Publikováno v:
Nature
Nature, 2022, 610 (7931), pp.343-348. ⟨10.1038/s41586-022-05068-3⟩
Nature, 2022, 610 (7931), pp.343-348. ⟨10.1038/s41586-022-05068-3⟩
Cancer progression is driven in part by genomic alterations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e11b6e4a3a2c6123cb66ae86667e677e
https://doi.org/10.1038/s41586-022-05068-3
https://doi.org/10.1038/s41586-022-05068-3