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of 15
pro vyhledávání: '"Isabelle, Pot"'
Autor:
Isabelle Pot, Shachi Patel, Lili Deng, Amrita Singh Chandhoke, Chi Zhang, Azad Bonni, Shirin Bonni
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e67178 (2013)
Transforming growth factor-beta (TGFβ) is a secreted polypeptide that plays essential roles in cellular development and homeostasis. Although mechanisms of TGFβ-induced responses have been characterized, our understanding of TGFβ signaling remains
Externí odkaz:
https://doaj.org/article/cdea068935584eafaf2f17c99dce5a40
Publikováno v:
Current Molecular Medicine. 10:667-673
The transcriptional regulator SnoN has been the subject of growing interest due to its diverse functions in normal and pathological settings. A large body of evidence has established a fundamental role for SnoN as a modulator of signaling and respons
Autor:
Isabelle Pot, Shirin Bonni
Publikováno v:
Current Molecular Medicine. 8:319-328
The Transforming Growth Factor (TGF)- beta-Smad signaling pathway regulates diverse biological processes essential for normal development and homeostasis. The Smad-interacting transcriptional modulator SnoN and its related homologs have emerged as im
Autor:
Ying-Han R. Hsu, Stuart J. Netherton, Krishna Pada Sarker, Shirin Bonni, Angela Chan, Isabelle Pot
Publikováno v:
Journal of Biological Chemistry. 281:33008-33018
The transcriptional modulator SnoN controls a diverse set of biological processes, including cell proliferation and differentiation. The mechanisms by which SnoN regulates these processes remain incompletely understood. Recent studies have shown that
Autor:
Isabelle Pot, Miles A. Pufall, Barbara J. Graves, Gregory M. Lee, Hyun Seo Kang, Lawrence P. McIntosh, Logan W. Donaldson
Publikováno v:
Journal of Biological Chemistry. 280:7088-7099
The transcription factor Ets-1 is regulated by the allosteric coupling of DNA binding with the unfolding of an alpha-helix (HI-1) within an autoinhibitory module. To understand the structural and dynamic basis for this autoinhibition, we have used NM
Autor:
Melanie L. Mayer, Hong Xu, Teresa Kwok, Michael Chang, Charles Boone, Philip Hieter, Rick Newitt, Isabelle Pot, Victoria Aneliunas, Grant W. Brown, Ruedi Aebersold
Publikováno v:
Molecular Biology of the Cell. 15:1736-1745
Ctf8p is a component of Ctf18-RFC, an alternative replication factor C-like complex required for efficient sister chromatid cohesion in Saccharomyces cerevisiae. We performed synthetic genetic array (SGA) analysis with a ctf8 deletion strain as a pri
Autor:
Eric G D Muller, Vivien Measday, Trisha N. Davis, Brian E. Snydsman, Isabelle Pot, Stanley Fields, Philip Hieter, Gerard Cagney
Publikováno v:
Molecular Biology of the Cell. 14:460-476
Kinetochore proteins contribute to the fidelity of chromosome transmission by mediating the attachment of a specialized chromosomal region, the centromere, to the mitotic spindle during mitosis. In budding yeast, a subset of kinetochore proteins, ref
Autor:
Stephen G. Withers, Isabelle Pot, Gary D. Brayer, Lawrence P. McIntosh, Manish D. Joshi, Gary Sidhu
Publikováno v:
Journal of Molecular Biology. 299:255-279
The pH optima of family 11 xylanases are well correlated with the nature of the residue adjacent to the acid/base catalyst. In xylanases that function optimally under acidic conditions, this residue is aspartic acid, whereas it is asparagine in those
Autor:
Isabelle, Pot, Shirin, Bonni
Publikováno v:
Current molecular medicine. 8(4)
The Transforming Growth Factor (TGF)- beta-Smad signaling pathway regulates diverse biological processes essential for normal development and homeostasis. The Smad-interacting transcriptional modulator SnoN and its related homologs have emerged as im
Autor:
Xiaolan Feng, Mai Anh Huynh, Stuart J. Netherton, Krishna Pada Sarker, Azad Bonni, Isabelle Pot, Karl Riabowol, Hiromi Kataoka, Angela Chan, Shirin Bonni
Publikováno v:
The Journal of biological chemistry. 283(19)
Members of the ING (inhibitor of growth) family of chromatin modifying proteins (ING1-ING5) have emerged as critical regulators of gene expression and cellular responses, suggesting that the ING proteins may impinge on specific signal transduction pa