Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Isabelle, Hatin"'
Autor:
Ismael Boussaid, Salomé Le Goff, Célia Floquet, Emilie-Fleur Gautier, Anna Raimbault, Pierre-Julien Viailly, Dina Al Dulaimi, Barbara Burroni, Isabelle Dusanter-Fourt, Isabelle Hatin, Patrick Mayeux, Bertrand Cosson, Michaela Fontenay
Publikováno v:
Haematologica, Vol 106, Iss 3 (2020)
In ribosomopathies, the Diamond-Blackfan anemia (DBA) or 5q- syndrome, ribosomal protein (RP) genes are affected by mutation or deletion, resulting in bone marrow erythroid hypoplasia. Unbalanced production of ribosomal subunits leading to a limited
Externí odkaz:
https://doaj.org/article/543009c502d445528cecd46a82c8736b
Autor:
Patrick C. Thiaville, Rachel Legendre, Diego Rojas-Benítez, Agnès Baudin-Baillieu, Isabelle Hatin, Guilhem Chalancon, Alvaro Glavic, Olivier Namy, Valérie de Crécy-Lagard
Publikováno v:
Microbial Cell, Vol 3, Iss 1, Pp 29-45 (2015)
The universal tRNA modification t6A is found at position 37 of nearly all tRNAs decoding ANN codons. The absence of t6A37 leads to severe growth defects in baker’s yeast, phenotypes similar to those caused by defects in mcm5s2U34 synthesis. Mutants
Externí odkaz:
https://doaj.org/article/337eae8a426e4ef0bebf392a38a8e42c
Autor:
Laure Bidou, Olivier Bugaud, Goulven Merer, Matthieu Coupet, Isabelle Hatin, Egor Chirkin, Sabrina Karri, Stéphane Demais, Pauline François, Jean-Christophe Cintrat, Olivier Namy
Publikováno v:
Proceedings of the National Academy of Sciences. 119
Premature termination codons (PTCs) account for 10 to 20% of genetic diseases in humans. The gene inactivation resulting from PTCs can be counteracted by the use of drugs stimulating PTC readthrough, thereby restoring production of the full-length pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1d681244d7efe64bcd9deee4d665104
https://doi.org/10.1073/pnas.2122004119
https://doi.org/10.1073/pnas.2122004119
Autor:
Agnès Baudin-Baillieu, Rachel Legendre, Claire Kuchly, Isabelle Hatin, Stéphane Demais, Claire Mestdagh, Daniel Gautheret, Olivier Namy
Publikováno v:
Cell Reports, Vol 8, Iss 2, Pp 439-448 (2014)
Prions are infectious proteins that can adopt a structural conformation that is then propagated among other molecules of the same protein. [PSI+] is an aggregated conformation of the translational release factor eRF3. [PSI+] modifies cellular fitness
Externí odkaz:
https://doaj.org/article/9b7bdff25c404eb881fa674d8f012b75
Autor:
François Morlé, Stéphane Giraudier, Eric Soler, Naomi Taylor, Charlotte Andrieu-Soler, Olivier Hermine, Patrick Mayeux, Célia Floquet, Rose Ann Padua, Frédérique Verdier, Sarah Ducamp, Michaela Fontenay, Mohammad Salma, Elisabeth M. Cramer-Borde, Ismael Boussaid, Anna Raimbault, Isabelle Hatin, Diane d'Allard, Amandine Houvert, Narla Mohandas, Boris Guyot, Emilie-Fleur Gautier, Sandrina Kinet, Marjorie Leduc, Pierre-Emmanuel Gleizes, Jean-Jacques Diaz, Salomé Le Goff, François Guillonneau, Nathalie Montel-Lehry
Publikováno v:
Blood
Blood, American Society of Hematology, 2021, 137 (1), pp.89-102. ⟨10.1182/blood.2019003439⟩
Blood, 2020, ⟨10.1182/blood.2019003439⟩
Blood, American Society of Hematology, 2020, ⟨10.1182/blood.2019003439⟩
Blood, American Society of Hematology, 2020, 137 (1), pp.89-102. ⟨10.1182/blood.2019003439⟩
Blood, 2021, 137 (1), pp.89-102. ⟨10.1182/blood.2019003439⟩
Blood, American Society of Hematology, 2021, 137 (1), pp.89-102. ⟨10.1182/blood.2019003439⟩
Blood, 2020, ⟨10.1182/blood.2019003439⟩
Blood, American Society of Hematology, 2020, ⟨10.1182/blood.2019003439⟩
Blood, American Society of Hematology, 2020, 137 (1), pp.89-102. ⟨10.1182/blood.2019003439⟩
Blood, 2021, 137 (1), pp.89-102. ⟨10.1182/blood.2019003439⟩
The role of ribosome biogenesis in erythroid development is supported by the recognition of erythroid defects in ribosomopathies in both Diamond-Blackfan anemia and 5q− syndrome. Whether ribosome biogenesis exerts a regulatory function on normal er
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6c14ec0b5187882ecdef968124a4606
https://doi.org/10.1182/blood.2019003439
https://doi.org/10.1182/blood.2019003439
Autor:
Emmanuel Labaronne, Didier Décimo, Lisa Bertrand, Laura Guiguettaz, Thibault J.M. Sohier, David Cluet, Valérie Vivet-Boubou, Clara Dahoui, Pauline François, Isabelle Hatin, Olivier Lambotte, Assia Samri, Brigitte Autran, Lucie Etienne, Caroline Goujon, Jean-Christophe Paillart, Olivier Namy, Berta Cecilia Ramirez, Théophile Ohlmann, Arnaud Moris, Emiliano P. Ricci
Human immunodeficiency virus type-1 (HIV-1) is a complex retrovirus which relies on alternative splicing, translational and post-translational mechanisms to produce more than 15 functional proteins from its single ∼10kb transcriptional unit. Here,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2760013a8a6df5b1a6a7defc1542a190
https://doi.org/10.1101/2022.04.29.489990
https://doi.org/10.1101/2022.04.29.489990
Autor:
Michaela Fontenay, Pierre-Julien Viailly, Bertrand Cosson, Patrick Mayeux, Anna Raimbault, Dina Al Dulaimi, Emilie-Fleur Gautier, Barbara Burroni, Isabelle Dusanter-Fourt, Ismael Boussaid, Salomé Le Goff, Célia Floquet, Isabelle Hatin
Publikováno v:
Haematologica
Haematologica, Ferrata Storti Foundation, 2020, ⟨10.3324/haematol.2019.239970⟩
Haematologica, 2020, ⟨10.3324/haematol.2019.239970⟩
Haematologica, Ferrata Storti Foundation, 2020, ⟨10.3324/haematol.2019.239970⟩
Haematologica, 2020, ⟨10.3324/haematol.2019.239970⟩
In ribosomopathies, the Diamond-Blackfan anemia (DBA) or 5q- syndrome, ribosomal protein (RP) genes are affected by mutation or deletion, resulting in bone marrow erythroid hypoplasia. Unbalanced production of ribosomal subunits leading to a limited
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e3952f914a173a95c75bac114754823
http://europepmc.org/articles/PMC7927886
http://europepmc.org/articles/PMC7927886
Autor:
Olivier Bugaud, Laure Bidou, Egor Chirkin, Pauline François, Isabelle Hatin, Olivier Namy, Matthieu Coupet, Jean-Christophe Cintrat, Goulven Merer
Premature termination codons (PTCs) account for 10% to 20% of genetic diseases in humans. The gene inactivation resulting from PTC can be counteracted by the use of drugs stimulating PTC readthrough, thereby restoring production of the full-length pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::686389776af4d9d47a2dfc6fd06943f7
https://doi.org/10.1101/2021.11.09.467859
https://doi.org/10.1101/2021.11.09.467859
Autor:
Olivier Namy, Anne Lopes, Isabelle Callebaut, Olivier Lespinet, Isabelle Hatin, Maxime Renard, Jean-Christophe Gelly, Chris Papadopoulos
The noncoding genome plays an important role in de novo gene birth and in the emergence of genetic novelty. Nevertheless, how noncoding sequences’ properties could promote the birth of novel genes and shape the evolution and the structural diversit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b8a2299ed88ab67356842453b74bebb4
https://doi.org/10.1101/2021.04.13.439703
https://doi.org/10.1101/2021.04.13.439703
Publikováno v:
PLoS Genetics, Vol 8, Iss 3, p e1002608 (2012)
The efficiency of translation termination depends on the nature of the stop codon and the surrounding nucleotides. Some molecules, such as aminoglycoside antibiotics (gentamicin), decrease termination efficiency and are currently being evaluated for
Externí odkaz:
https://doaj.org/article/3ba02b3d5d0149ea900e25bb7748d488