Bioavailability of Melatonin after Administration of an Oral Prolonged-Release Tablet and an Immediate-Release Sublingual Spray in Healthy Male Volunteers

Autor: Samira Ait Abdellah, Véronique Raverot, Caroline Gal, Isabelle Guinobert, Valérie Bardot, Claude Blondeau, Bruno Claustrat

Publikováno v: Drugs in R&D, Vol 23, Iss 3, Pp 257-265 (2023)

Abstract Background The benefit of exogenous melatonin is based on its bioavailability, which depends on the galenic form, the route of administration, the dosage, and the individual absorption and rate of hepatic metabolism. Objective The objective

Externí odkaz: https://doaj.org/article/ae63969384f4465eb47e9ab4bad048b8

Skeletal muscle relaxant effect of a standardized extract of Valeriana officinalis L. after acute administration in mice

Autor: Dorian Caudal, Isabelle Guinobert, Aude Lafoux, Valérie Bardot, César Cotte, Isabelle Ripoche, Pierre Chalard, Corinne Huchet

Publikováno v: Journal of Traditional and Complementary Medicine, Vol 8, Iss 2, Pp 335-340 (2018)

Valeriana officinalis L. root extracts are traditionally taken for their sedative and anxiolytic properties and are also used for muscle relaxation. Relaxant effects were clearly observed on smooth muscle whereas data on effects on skeletal muscle ar

Externí odkaz: https://doaj.org/article/55c853af41b842dbab060964a0a3d828

A combination of Eschscholtzia californica Cham. and Valeriana officinalis L. extracts for adjustment insomnia: A prospective observational study

Autor: Marc Beck, Isabelle Guinobert, Aurélie Berlin, François Duforez, Samira Ait Abdellah, Angèle Guilbot, Claude Blondeau

Publikováno v: Journal of Traditional and Complementary Medicine
Journal of Traditional and Complementary Medicine, Vol 10, Iss 2, Pp 116-123 (2020)

Eschscholtzia californica Cham. and Valeriana officinalis L. have long been used for the management of sleep disorders and anxiety. Use of a fixed combination of these two plant extracts (Phytostandard® d’Eschscholtzia et de Valériane, PiLeJe Lab

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a64c2a9aacbcda5e79949c0d582a76cf
https://doi.org/10.1016/j.jtcme.2019.02.003

The Use of Natural Agents to Counteract Telomere Shortening: Effects of a Multi-Component Extract of Astragalus mongholicus Bunge and Danazol

Autor: Georges Deschenes, Lucile Berthomier, Isabelle Ripoche, Claude Blondeau, Patrice Carde, Isabelle Guinobert, Eric Jeandidier, Bruno Colicchio, Radhia M'kacher, César Cotte, Noufissa Oudrhiri, Alain Dieterlen, Valérie Bardot

Publikováno v: Biomedicines, Vol 8, Iss 2, p 31 (2020)
Biomedicines
Biomedicines, 2020, 8 (2), pp.31. ⟨10.3390/biomedicines8020031⟩
Biomedicines, MDPI, 2020, 8 (2), pp.31. ⟨10.3390/biomedicines8020031⟩
Volume 8
Issue 2

A link between telomere shortening and oxidative stress was found in aging people and patients with cancer or inflammatory diseases. Extracts of Astragalus spp. are known to stimulate telomerase activity, thereby compensating telomere shortening. We

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::818cf35c12912b4fe034e7d19208af9c
https://www.mdpi.com/2227-9059/8/2/31

Skeletal muscle relaxant effect of a standardized extract of Valeriana officinalis L. after acute administration in mice

Autor: D. Caudal, Valérie Bardot, César Cotte, Pierre Chalard, A. Lafoux, Isabelle Guinobert, Isabelle Ripoche, Corinne Huchet

Publikováno v: Journal of Traditional and Complementary Medicine
Journal of Traditional and Complementary Medicine, 2018, 8 (2), pp.335-340. ⟨10.1016/j.jtcme.2017.06.011⟩
Journal of Traditional and Complementary Medicine, Vol 8, Iss 2, Pp 335-340 (2018)

Valeriana officinalis L. root extracts are traditionally taken for their sedative and anxiolytic properties and are also used for muscle relaxation. Relaxant effects were clearly observed on smooth muscle whereas data on effects on skeletal muscle ar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b663eff97d03db31cd46aa0369d50abf
https://doi.org/10.1016/j.jtcme.2017.06.011