Zobrazeno 1 - 10
of 311
pro vyhledávání: '"Isabelle, Fournier"'
Autor:
Marie-Océane Laguillaumie, Sofia Titah, Aurélie Guillemette, Bernadette Neve, Frederic Leprêtre, Pascaline Ségard, Faruk Azam Shaik, Dominique Collard, Jean-Claude Gerbedoen, Léa Fléchon, Lama Hasan Bou Issa, Audrey Vincent, Martin Figeac, Shéhérazade Sebda, Céline Villenet, Jérôme Kluza, William Laine, Isabelle Fournier, Jean-Pascal Gimeno, Maxence Wisztorski, Salomon Manier, Mehmet Cagatay Tarhan, Bruno Quesnel, Thierry Idziorek, Yasmine Touil
Publikováno v:
Biological Research, Vol 57, Iss 1, Pp 1-28 (2024)
Abstract Background Tumour dormancy, a resistance mechanism employed by cancer cells, is a significant challenge in cancer treatment, contributing to minimal residual disease (MRD) and potential relapse. Despite its clinical importance, the mechanism
Externí odkaz:
https://doaj.org/article/a30941614df749d1805f6f87c1b51f5b
Publikováno v:
STAR Protocols, Vol 5, Iss 3, Pp 103285- (2024)
Summary: In context of cancer diagnosis-based mass spectrometry (MS), the classification model created is crucial. Moreover, exploration of immune cell infiltration in tissues can offer insights within the tumor microenvironment. Here, we present a p
Externí odkaz:
https://doaj.org/article/a48a2bc880c842258987f30ab2324973
Publikováno v:
Audiology Research, Vol 14, Iss 2, Pp 304-316 (2024)
Objective: This study aimed to evaluate the effectiveness of endolymphatic duct blockage (EDB) on dizziness control in patients with a large vestibular aqueduct (LVA) and to evaluate its effect on hearing. Study design: This is a prospective nonrando
Externí odkaz:
https://doaj.org/article/bb50eac66e4d409f9083c32634e84e5f
Autor:
Nilmara de Oliveira Alves, Guillaume Dalmasso, Darja Nikitina, Amaury Vaysse, Richard Ruez, Lea Ledoux, Thierry Pedron, Emma Bergsten, Olivier Boulard, Lora Autier, Sofian Allam, Laurence Motreff, Pierre Sauvanet, Diane Letourneur, Pragya Kashyap, Johan Gagnière, Denis Pezet, Catherine Godfraind, Michel Salzet, Emmanuel Lemichez, Mathilde Bonnet, Imène Najjar, Christophe Malabat, Marc Monot, Denis Mestivier, Nicolas Barnich, Pankaj Yadav, Isabelle Fournier, Sean Kennedy, Amel Mettouchi, Richard Bonnet, Iradj Sobhani, Mathias Chamaillard
Publikováno v:
Gut Microbes, Vol 16, Iss 1 (2024)
ABSTRACTIntratumoral bacteria flexibly contribute to cellular and molecular tumor heterogeneity for supporting cancer recurrence through poorly understood mechanisms. Using spatial metabolomic profiling technologies and 16SrRNA sequencing, we herein
Externí odkaz:
https://doaj.org/article/8c88e5e7aa7c4e8590455a2c80f8cc28
Autor:
Maxence Wisztorski, Soulaimane Aboulouard, Lucas Roussel, Marie Duhamel, Philippe Saudemont, Tristan Cardon, Fabrice Narducci, Yves-Marie Robin, Anne-Sophie Lemaire, Delphine Bertin, Nawale Hajjaji, Firas Kobeissy, Eric Leblanc, Isabelle Fournier, Michel Salzet
Publikováno v:
Cell Death and Disease, Vol 14, Iss 9, Pp 1-20 (2023)
Abstract Ovarian cancer is the leading cause of death from gynecologic cancer worldwide. High-grade serous carcinoma (HGSC) is the most common and deadliest subtype of ovarian cancer. While the origin of ovarian tumors is still debated, it has been s
Externí odkaz:
https://doaj.org/article/94827e08cedd45c58c16124d156e2fae
Autor:
Alice Capuz, Sylvain Osien, Tristan Cardon, Mélodie Anne Karnoub, Soulaimane Aboulouard, Antonella Raffo-Romero, Marie Duhamel, Dasa Cizkova, Marco Trerotola, David Devos, Firas Kobeissy, Fabien Vanden Abeele, Amélie Bonnefond, Isabelle Fournier, Franck Rodet, Michel Salzet
Publikováno v:
Cell Death and Disease, Vol 14, Iss 8, Pp 1-23 (2023)
Abstract The dogma “One gene, one protein” is clearly obsolete since cells use alternative splicing and generate multiple transcripts which are translated into protein isoforms, but also use alternative translation initiation sites (TISs) and ter
Externí odkaz:
https://doaj.org/article/c1f0c4f332644e5aa7a4c789a3d99d88
Autor:
Alice Capuz, Sylvain Osien, Mélodie Anne Karnoub, Soulaimane Aboulouard, Estelle Laurent, Etienne Coyaud, Antonella Raffo-Romero, Marie Duhamel, Amélie Bonnefond, Mehdi Derhourhi, Marco Trerotola, Ikram El Yazidi-Belkoura, David Devos, Monika Zilkova, Firas Kobeissy, Fabien Vanden Abeele, Isabelle Fournier, Dasa Cizkova, Franck Rodet, Michel Salzet
Publikováno v:
Cell Death and Disease, Vol 14, Iss 4, Pp 1-16 (2023)
Abstract Using multi-omics analyses including RNAseq, RT-PCR, RACE-PCR, and shotgun proteomic with enrichment strategies, we demonstrated that newborn rat astrocytes produce neural immunoglobulin constant and variable heavy chains as well as light ch
Externí odkaz:
https://doaj.org/article/4a879d4e7d604bcc8c22d0f2991b82bb
Publikováno v:
STAR Protocols, Vol 4, Iss 3, Pp 102380- (2023)
Summary: Since the start of mass-spectrometry-based proteomics, proteins from non-referenced open reading frames or alternative proteins (AltProts) have been overlooked. Here, we present a protocol to identify human subcellular AltProt and decipher s
Externí odkaz:
https://doaj.org/article/50ee1b2a3323448088474cc052088529
Autor:
Antonella Raffo-Romero, Soulaimane Aboulouard, Emmanuel Bouchaert, Agata Rybicka, Dominique Tierny, Nawale Hajjaji, Isabelle Fournier, Michel Salzet, Marie Duhamel
Publikováno v:
BMC Biology, Vol 21, Iss 1, Pp 1-19 (2023)
Abstract Background Cancer heterogeneity is a main obstacle for the development of effective therapies, as its replication in in vitro preclinical models is challenging. Around 96% of developed drugs are estimated to fail from discovery to the clinic
Externí odkaz:
https://doaj.org/article/ed36d527f98a4f21a823d059c58969d4
Autor:
Marie Duhamel, Lauranne Drelich, Maxence Wisztorski, Soulaimane Aboulouard, Jean-Pascal Gimeno, Nina Ogrinc, Patrick Devos, Tristan Cardon, Michael Weller, Fabienne Escande, Fahed Zairi, Claude-Alain Maurage, Émilie Le Rhun, Isabelle Fournier, Michel Salzet
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Characterisation of molecular heterogeneity in glioblastoma would improve patient stratification. Here, the authors integrate spatial proteomics and clinical data from glioblastoma patients and identify 3 molecular groups and a 5-protein signature th
Externí odkaz:
https://doaj.org/article/a3c577b117894ed0860c09c147501935