Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Isabelle, Fakhoury"'
Publikováno v:
Journal of Ovarian Research, Vol 14, Iss 1, Pp 1-13 (2021)
Abstract Ovarian carcinoma is the second most common malignancy of the female reproductive system and the leading cause of death from female reproductive system malignancies. Cancer cells have increased proliferation rate and thus require high amount
Externí odkaz:
https://doaj.org/article/042919373684419daae46922977d6156
Autor:
Sandra Abdellatef, Isabelle Fakhoury, Maria Al Haddad, Leila Jaafar, Hiba Maalouf, Samer Hanna, Bassem Khalil, Zeinab El Masri, Louis Hodgson, Mirvat El-Sibai
Publikováno v:
European Journal of Cell Biology, Vol 101, Iss 1, Pp 151197- (2022)
Metastasis remains the main challenge to overcome for treating ovarian cancers. In this study, we investigate the potential role of the Cdc42 GAP StarD13 in the modulation of cell motility, invasion in ovarian cancer cells. StarD13 depletion does not
Externí odkaz:
https://doaj.org/article/c030646bb245450f846b4f07b00e9590
Autor:
Nada El Baba, Mohammad Farran, Elie Abi Khalil, Leila Jaafar, Isabelle Fakhoury, Mirvat El-Sibai
Publikováno v:
Analytical Cellular Pathology, Vol 2020 (2020)
Vascular endothelial growth factors (VEGFs) consist of five molecules (VEGFA through D as well as placental growth factor) which are crucial for regulating key cellular and tissue functions. The role of VEGF and its intracellular signaling and downst
Externí odkaz:
https://doaj.org/article/a2457c03d5f94bfba1e2e88b9cfd517e
Publikováno v:
International Journal of Oncology. 62
Genetic alterations drive tumor onset and progression. However, the cross‑talk between tumor cells and the benign components of the surrounding stroma can also promote the initiation, progression and metastasis of solid tumors. These cellular and n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77f38bda628ba5fcf79457e914957f28
https://doi.org/10.3892/ijo.2022.5471
https://doi.org/10.3892/ijo.2022.5471
Autor:
Isabelle Fakhoury, Mirvat El-Sibai, Ralph J. Abi-Habib, Sarah Nohra, Nour El-Mais, Maria Al Haddad
Publikováno v:
Pancreas. 50:1187-1194
OBJECTIVES Pancreatic cancer is one of the most aggressive solid cancers and the fourth leading cause of cancer death in men and women. We previously showed that arginine depletion, using arginase I [HuArgI(Co)-PEG5000], selectively triggers cell dea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f65894c29364640466c0de55f2573cc3
https://doi.org/10.1097/mpa.0000000000001891
https://doi.org/10.1097/mpa.0000000000001891
Autor:
Marwa Al Hassan, Isabelle Fakhoury, Zeinab El Masri, Noura Ghazale, Rayane Dennaoui, Oula El Atat, Amjad Kanaan, Mirvat El-Sibai
Publikováno v:
Analytical Cellular Pathology, Vol 2018 (2018)
Glioblastoma multiforme (GBM) is one of the most common and deadliest cancers of the central nervous system (CNS). GBMs high ability to infiltrate healthy brain tissues makes it difficult to remove surgically and account for its fatal outcomes. To im
Externí odkaz:
https://doaj.org/article/9dd354fd96cd40369f082d41a38cc0a5
Publikováno v:
Cells, Vol 8, Iss 11, p 1397 (2019)
Glioblastoma multiforme (GBM) is one of the most common and deadly cancers of the central nervous system (CNS). It is characterized by the presence of hypoxic regions, especially in the core, leading to an increase in vascularity. This increased vasc
Externí odkaz:
https://doaj.org/article/223eddaf003f4210b940fc378f6ef8a8
Autor:
Leila Jaafar, Isabelle Fakhoury, Wassim Abou-Kheir, Mirvat El-Sibai, Layal El-Hajjar, Sahar Saab
Publikováno v:
Human Cell. 34:607-623
Prostate cancer is the second most commonly diagnosed cancer in men and one of the main leading causes of cancer deaths among men worldwide. Rapid uncontrolled growth and the ability to metastasize to other sites are key hallmarks in cancer developme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dc15d2144fb11ad57a29b8274d03b31
https://doi.org/10.1007/s13577-020-00479-8
https://doi.org/10.1007/s13577-020-00479-8
Autor:
Mirvat El-Sibai, Mirna Swayden, Amira Bekdash, Oula El-Atat, Isabelle Fakhoury, Ralph J. Abi-Habib, Jamila Borjac-Natour
Publikováno v:
Human Cell. 34:152-164
Deregulating cellular energetics by reprogramming metabolic pathways, including arginine metabolism, is critical for cancer cell onset and survival. Drugs that target the specific metabolic requirements of cancer cells have emerged as promising targe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edb4bf60cb22fe3ba2d2c0fa5b8e2934
https://doi.org/10.1007/s13577-020-00437-4
https://doi.org/10.1007/s13577-020-00437-4
Publikováno v:
Journal of Ovarian Research
Journal of Ovarian Research, Vol 14, Iss 1, Pp 1-13 (2021)
Journal of Ovarian Research, Vol 14, Iss 1, Pp 1-13 (2021)
Ovarian carcinoma is the second most common malignancy of the female reproductive system and the leading cause of death from female reproductive system malignancies. Cancer cells have increased proliferation rate and thus require high amounts of amin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a1bff0de4b41e815d03615dfaaf754a
https://doi.org/10.1186/s13048-021-00767-3
https://doi.org/10.1186/s13048-021-00767-3