Výsledky vyhledávání - "Isabelle, Dubus"

Improvement of dexamethasone sensitivity by chelation of intracellular Ca2+ in pediatric acute lymphoblastic leukemia cells through the prosurvival kinase ERK1/2 deactivation

Autor: Jean-Pierre Vannier, Souleymane Abdoul-Azize, Isabelle Dubus

Publikováno v: Oncotarget
Oncotarget, Impact journals, 2017, 8 (16), pp.27339-27352. ⟨10.18632/oncotarget.16039⟩

// Souleymane Abdoul-Azize 1, 3 , Isabelle Dubus 1, 3 , Jean-Pierre Vannier 1, 2, 3 1 Micro-Environnement et Renouvellement Cellulaire Integre, MERCI UPRES EA 3829, Faculte de Medecine et Pharmacie, Universite de Rouen, 76183 Rouen Cedex, France 2 Se

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c990a2eb1841a0e9145f281d34a2b6a
https://hal-normandie-univ.archives-ouvertes.fr/hal-02374408

Zobrazit plný text záznamu

Hypoxia promotes chemoresistance in acute lymphoblastic leukemia cell lines by modulating death signaling pathways

Autor: C. Heuclin, C. Petit, Isabelle Dubus, J. P. Vannier, Flore Gouel, K. Roget

Publikováno v: BMC Cancer
BMC Cancer, BioMed Central, 2016, 16, pp.746. ⟨10.1186/s12885-016-2776-1⟩

Background Several studies show that bone marrow (BM) microenvironment and hypoxia condition can promote the survival of leukemic cells and induce resistance to anti-leukemic drugs. However, the molecular mechanism for chemoresistance by hypoxia is n

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7abbc183743a232d2e86e81257939187
https://doi.org/10.1186/s12885-016-2776-1

Zobrazit plný text záznamu

Pyr3, a TRPC3 channel blocker, potentiates dexamethasone sensitivity and apoptosis in acute lymphoblastic leukemia cells by disturbing Ca2+ signaling, mitochondrial membrane potential changes and reactive oxygen species production

Autor: Souleymane Abdoul-Azize, Isabelle Dubus, Catherine Buquet, Jean-Pierre Vannier

Publikováno v: European Journal of Pharmacology
European Journal of Pharmacology, Elsevier, 2016, 784, pp.90-98. ⟨10.1016/j.ejphar.2016.05.014⟩

International audience; Dexamethasone (Dex) is used as a chemotherapeutic drug in the treatment of acute lymphoblastic leukemia (ALL) because of its capacity to induce apoptosis. However, some ALL patients acquire resistance to glucocorticoids (GC).

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd4122def2dacf8f93fdb33b69d05142
https://hal-normandie-univ.archives-ouvertes.fr/hal-02374419

Zobrazit plný text záznamu

Importance of local hypoxia on endothelial phenotype for an in vitro approach to bone marrow angiogenesis

Autor: Marc Vasse, Jean-Pierre Vannier, Isabelle Dubus, Sophie Kamanzi, Flore Gouel, Cécile Corbière, Paul Mulder, Elisabeth Legrand, Catherine Buquet

Publikováno v: Leukemia Research
Leukemia Research, Elsevier, 2012, 36 (9), pp.1200-1203. ⟨10.1016/j.leukres.2012.05.026⟩

International audience; The vasculature of bone marrow differs from that in other organs, and its characteristics should be considered when exploring the medullar angiogenesis associated with hematological malignancies. We show here that the human bo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::394d509929bf4c76f6ca501302d11a74
https://doi.org/10.1016/j.leukres.2012.05.026

Zobrazit plný text záznamu

What Role for Angiogenesis in Childhood Acute Lymphoblastic Leukaemia?

Autor: Isabelle Dubus, Flore Gouel, E. Legrand, Pascale Schneider, Marc Vasse, Vannier Jp

Publikováno v: Advances in Hematology, Vol 2011 (2011)
Advances in Hematology

The role of angiogenesis in acute leukaemia has been discussed since the cloning of the gene ofvascular endothelial growth factor(VEGF) from the acute myelogenous leukemia cell line (HL60) and, thereafter, when the first studies reported increased bo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d6d67cd23e050de86d00b641fef290f
https://doi.org/10.1155/2011/274628

Zobrazit plný text záznamu

Liste des auteurs

Autor: Elise, Belaidi-Corsat, Sylvie, Bobillier-Chaumont devaux, Anne, Briancon, Delphine, Carbonnelle, Abdeslam, Chagraoui, Christine, Courteix, Daniel, Cussac, Catherine, David, Patrick, Duriez, Thomas, Freret, Éric, Le Ferrec, Samuel, Legeay, Karine, Maheo, Valérie, Nivet-Antoine, Jean-François, Quignard, Pascale, Schumann-Bard, Benoit, Sion, Anne, Tessier, Catherine, Vergely, Jean-Marie, Bard, Marie-Lise, Bats, Bruno, Baudin, Jean-François, Benoist, Laurent, Bermont, Edith, Bigot-Corbel, Didier, Borderie, Thierry, Brousseau, Sylvie, Labrouche-Colomer, Jeanne, Cook-Moreau, Isabelle, Dubus, Nazih, El-Hassane, Anthony, Fourier, Philippe, Gervois, Nicolas, Goncalves-Mendez, Guillaume, Grzych, Isabelle, Hininger-Favier, Apolline, Imbard, Saïd, Kamel, Geneviève, Lacape, Fanny, Lalloyer, Karen, Lambert-Cordillac, Jean-Marc, Lessinger, Bertrand, Liagre, Sophie, Mary, Pascal, Philibert, Eléonore, Real, Sophie, Séronie-Vivien, Anne, Tailleux, Patrice, Therond, Pascale, Vergne-Salle, Julie, Davaze-Schneider, Lila, Rami-Arab

Publikováno v: In Biochimie – Physiologie – Physiopathologie 2023:vii-viii

Zobrazit plný text záznamu

Rac-1 GTPase controls the capacity of human leukaemic lymphoblasts to migrate on fibronectin in response to SDF-1α (CXCL12)

Autor: Isabelle Dubus, Catherine Buquet, Flore Gouel, Elisabeth Legrand, Marc Vasse, Jean-Pierre Vannier, Manuel Fréret

Publikováno v: Leukemia Research. 35:971-973

Acute lymphoblastic leukaemia (ALL) is characterized by malignant cell infiltration of bone marrow, requiring chemotactic response to SDF-1α. Using time-lapse video, we measured the velocity of ALL cells on fibronectin, and found that SDF-1α increa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e410117695544e2097c82d7bfd837ab4
https://doi.org/10.1016/j.leukres.2011.03.011

Zobrazit plný text záznamu

Importance of ERK activation in As2O3-induced differentiation and promyelocytic leukemia nuclear bodies formation in neuroblastoma cells

Autor: Marc Vasse, J.-P. Goullé, Isabelle Dubus, A. Petit, Anthony Falluel-Morel, Vannier Jp, Anthony Delaune

Publikováno v: Pharmacological research. 77

Neuroblastoma malignant cell growth is dependent on their undifferentiated status. Arsenic trioxide (As2O3) induces neuroblastoma cell differentiation in vitro, but its mechanisms still remains unknown. We used three human neuroblastoma cell lines (S

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24d8ea0e906053cf104c560189fbbf9a
https://pubmed.ncbi.nlm.nih.gov/24004656

Zobrazit plný text záznamu

Elastin-derived peptides: matrikines critical for glioblastoma cell aggressiveness in a 3-D system

Autor: Virginie Dulong, Isabelle Dubus, Annie Reber, Frederic Torossian, Jean-Pierre Vannier, Bérénice Coquerel, Georges Bellon, Florent Poyer

Publikováno v: Glia
Glia, Wiley, 2009, 57 (16), pp.1716-1726
Glia, Wiley, 2009, 57 (16), pp.1716-1726. ⟨10.1002/glia.20884⟩

In the most common primary brain tumors, malignant glioma cells invade the extracellular matrix (ECM) and proliferate rapidly in the cerebral tissue, which is mainly composed of hyaluronan (HA) along with the elastin present in the basement membrane

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c2db0168ab51ea4d38f18928297e214
https://hal.archives-ouvertes.fr/hal-00436350

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání