Výsledky vyhledávání - "Isabella dos Santos Guimarães"

Akademický článek

Evaluation of HIF-1α and VEGF-A expression in radiation-induced cystitis: A case-control study

Autor: Ricardo Castellani de Mattos, Isabella dos Santos Guimarães, Leandro de Souza Thiago, Andreia Cristina de Melo

Publikováno v: International Brazilian Journal of Urology, Vol 47, Iss 2, Pp 295-305 (2021)

ABSTRACT The standard treatment for locally advanced cervical cancer (CC) is chemoradiotherapy. Once the bladder receives part of the radiation, a typical inflammatory condition that configures radiation-induced cystitis may develop. Chronic radiatio

Externí odkaz: https://doaj.org/article/63b316237b1c4b89b5f95c188b4c7868

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Akademický článek

Cytotoxicity and Pro-Apoptotic, Antioxidant and Anti-Inflammatory Activities of Geopropolis Produced by the Stingless Bee Melipona fasciculata Smith

Autor: Josianne Rocha Barboza, Francisco Assis Nascimento Pereira, Renan Amphilophio Fernandes, Cleydlenne Costa Vasconcelos, Maria do Socorro de Sousa Cartágenes, Alberto Jorge Oliveira Lopes, Andreia Cristina de Melo, Isabella dos Santos Guimarães, Cláudia Quintino da Rocha, Maria Nilce de Sousa Ribeiro

Publikováno v: Biology, Vol 9, Iss 9, p 292 (2020)

Geopropolis is produced by some stingless bee species, such as Melipona fasciculata Smith, a native species from Brazil. This study aims to investigate the antioxidant and anti-inflammatory activities and cytotoxicity effects of geopropolis hydroetha

Externí odkaz: https://doaj.org/article/fca037b7e5734310adf7708f87353b0b

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Akademický článek

Amazon Fruits Inhibit Growth and Promote Pro-apoptotic Effects on Human Ovarian Carcinoma Cell Lines

Autor: Vanessa Rosse de Souza, Mariana Concentino Menezes Brum, Isabella dos Santos Guimarães, Paula de Freitas dos Santos, Thuane Oliveira do Amaral, Joel Pimentel Abreu, Thuane Passos, Otniel Freitas-Silva, Etel Rodrigues Pereira Gimba, Anderson Junger Teodoro

Publikováno v: Biomolecules, Vol 9, Iss 11, p 707 (2019)

Murici (Byrsonima crassifolia (L.) Kunth and B. verbascifolia (L.) DC.) and tapereba (Spondias mombin) are Amazonian fruits that contain bioactive compounds. Biochemical and molecular characterization of these fruits can reveal their potential use in

Externí odkaz: https://doaj.org/article/706a78e3814f4a8eb9561dd2659cf2fd

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Akademický článek

Metformin synergistically enhances antiproliferative effects of cisplatin and etoposide in NCI-H460 human lung cancer cells

Autor: Sarah Fernandes Teixeira, Isabella dos Santos Guimarães, Klesia Pirola Madeira, Renata Dalmaschio Daltoé, Ian Victor Silva, Leticia Batista Azevedo Rangel

Publikováno v: Jornal Brasileiro de Pneumologia, Vol 39, Iss 6, Pp 644-649 (2013)

OBJECTIVE: To test the effectiveness of combining conventional antineoplastic drugs (cisplatin and etoposide) with metformin in the treatment of non-small cell lung cancer in the NCI-H460 cell line, in order to develop new therapeutic options with hi

Externí odkaz: https://doaj.org/article/1f4ecfc6cecb4e6e91d2332ac58d6d32

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Synthetic Naphthoquinone Derivatives as Anticancer Agents in Ovarian Cancer: Cytotoxicity Assay and Investigation of Possible Biological Mechanisms Action

Autor: Renata Dalmaschio Daltoé, Leticia Batista Azevedo Rangel, Maicon Delarmelina, Klesia Pirola Madeira, Marcella Leite Porto, Silvana Santos Meirelles, Isabella dos Santos Guimarães, Éclair Venturini Filho, Alan Reinke Pereira, Rafael de Queiroz Ferreira, Gabriel Fernandes Souza dos Santos, Izabela de França Schaffel, José Walkimar de Mesquita Carneiro, Artur M. S. Silva, Sandro José Greco

Publikováno v: Chemistry & Biodiversity. 20

In this study, eight naphthoquinone derivatives were synthesized in yields ranging from 52 to 96% using easy, fast, and low-cost methodologies. All naphthoquinone derivatives were screened for their in vitro anti-proliferative activities against OVCA

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4fcefddf5f828b81f0c18a8c25d91e3
https://doi.org/10.1002/cbdv.202200807

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Inhibition of CXCR2 plays a pivotal role in re-sensitizing ovarian cancer to cisplatin treatment

Autor: Nayara G. Tessarollo, Raquel Maria da Silva Graça Almeida, Luísa Pereira, Diandra Zipinotti dos Santos, Ian Victor Silva, Patrícia Mesquita, Isabella dos Santos Guimarães, Diana Pádua, Paulo Cilas Morais Lyra-Junior, Leticia Batista Azevedo Rangel, Taciane B. Henriques, Ana Luísa Amaral, Bruno Cavadas

Publikováno v: Aging (Albany NY)

cDNA microarray data conducted by our group revealed overexpression of CXCL2 and CXCL8 in ovarian cancer (OC) microenvironment. Herein, we have proven that the chemokine receptor, CXCR2, is a pivotal molecule in re-sensitizing OC to cisplatin, and it

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::266f80a44ca46963219824b5b8e237d4
https://doi.org/10.18632/aging.203074

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(3,3’-Methylene)bis-2-hydroxy-1,4-naphthoquinones induce cytotoxicity against DU145 and PC3 cancer cells by inhibiting cell viability and promoting cell cycle arrest

Autor: Fernando de C. da Silva, David R. da Rocha, R. Ribeiro, Caroline S. Moreira, Isabella dos Santos Guimarães, Paula Priscilla de Freitas, Etel Rodrigues Pereira Gimba, Vitor F. Ferreira

Publikováno v: Molecular Biology Reports. 48:3253-3263

We developed a novel method for the synthesis of bis-naphthoquinones (BNQ), which are hybrids of lawsone (2-hydroxy-1,4-naphthoquinone) and 3-hydroxy-juglone (3,5-dihydroxy-1,4-naphthoquinone). The anticancer activity of three synthesized compounds,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f4270dfda1c27c3f1fc9fa40acef164d
https://doi.org/10.1007/s11033-021-06406-w

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Osteopontin‑c isoform inhibition modulates ovarian cancer cell cisplatin resistance, viability and plasticity

Autor: Mariana Concentino Menezes Brum, Leticia Batista Azevedo Rangel, Isabella dos Santos Guimarães, Luciana Ferreira, Raquel Ciuvalschi Maia, Etel Rodrigues Pereira Gimba, Gabriela Nestal de Moraes

Publikováno v: Oncology Reports

Osteopontin (OPN) is upregulated in several types of tumor and has been associated with chemoresistance. However, the contribution of OPN splicing isoforms (OPN‑SIs) to chemoresistance requires further investigation. The present study aimed to eval

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0a4f66bdc9e187b7cab5a9140a3aa34
https://doi.org/10.3892/or.2020.7877

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Evaluation of HIF-1α and VEGF-A expression in radiation-induced cystitis: A case-control study

Autor: Leandro de Souza Thiago, Isabella dos Santos Guimarães, Andreia Cristina de Melo, Ricardo Castellani de Mattos

Publikováno v: International braz j urol v.47 n.2 2021
International Braz J Urol
Sociedade Brasileira de Urologia (SBU)
instacron:SBU
International Brazilian Journal of Urology : official journal of the Brazilian Society of Urology
International Brazilian Journal of Urology, Vol 47, Iss 2, Pp 295-305 (2021)
International braz j urol, Volume: 47, Issue: 2, Pages: 295-305, Published: 05 FEB 2021

The standard treatment for locally advanced cervical cancer (CC) is chemoradiotherapy. Once the bladder receives part of the radiation, a typical inflammatory condition that configures radiation-induced cystitis may develop. Chronic radiation-induced

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::911ec74a7d08e69d5993eebb44e8f2c7
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1677-55382021000200295

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