Zobrazeno 1 - 10
of 135
pro vyhledávání: '"Isabella Taylor"'
Autor:
Charles G. Eberhart, Madhuri Kambhampati, Marianne Hütt-Cabezas, Howard T. Chang, Eric H. Raabe, Isabella Taylor, Javad Nazarian, Katherine E. Warren, William D. Brandt
Publikováno v:
Journal of Neuropathology & Experimental Neurology. 74:778-790
NOTCH regulates stem cells during normal development and stemlike cells in cancer, but the roles of NOTCH in the lethal pediatric brain tumor diffuse intrinsic pontine glioma (DIPG) remain unknown. Because DIPGs express stem cell factors such as SOX2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e900c4b6a8c506b626d07f0a7e8a2a80
https://doi.org/10.1097/nen.0000000000000216
https://doi.org/10.1097/nen.0000000000000216
Autor:
Javad Nazarian, Charles G. Eberhart, Manabu Natsumeda, Sridevi Yadavilli, Madhuri Kambhampati, Katherine E. Warren, Eric H. Raabe, Jeffrey Rubens, Harpreet Kaur, Louis Rodgers, Laura Asnaghi, Hiroaki Miyahara, Isabella Taylor
Diffuse intrinsic pontine glioma (DIPG) is an invasive and treatment-refractory pediatric brain tumor. Primary DIPG tumors harbor a number of mutations including alterations in PTEN, AKT, and PI3K and exhibit activation of mammalian Target of Rapamyc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49f842027ca200c79ff4726db6e8c8b2
https://europepmc.org/articles/PMC5569904/
https://europepmc.org/articles/PMC5569904/
Autor:
Guido Nikkhah, Xing Gang Mao, Ulf Dietrich Kahlert, Charles G. Eberhart, Isabella Taylor, Eric H. Raabe, Marianne Hütt-Cabezas, Brent A. Orr, Anand K.D. Rajan, Melanie Weingart, Yazmin Odia, Jarek Maciaczyk
Publikováno v:
Oncotarget
The cellular reprogramming factor LIN28A promotes tumorigenicity in cancers arising outside the central nervous system, but its role in brain tumors is unknown. We detected LIN28A protein in a subset of human gliomas observed higher expression in gli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16eeb631d7b6ef7f0d7c8b23a9dc81cb
https://doi.org/10.18632/oncotarget.1131
https://doi.org/10.18632/oncotarget.1131
Publikováno v:
Neurology. 80:1322-1329
OBJECTIVE: To use family studies to investigate the clinical genetics of photosensitivity to understand the interrelationship of different photosensitive epilepsy syndromes. METHODS: Twenty-nine families were recruited in which at least 2 members had
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7399502b7d769a0b5f7a354ceca6c046
https://doi.org/10.1212/wnl.0b013e31828ab349
https://doi.org/10.1212/wnl.0b013e31828ab349
Autor:
Eric H. Raabe, Micah J. Maxwell, Isabella Taylor, Brad Poore, Charles G. Eberhart, Jeffrey Rubens, Allison Hanaford
Publikováno v:
Cancer Research. 77:3549-3549
Glioblastoma (GBM) is among the most lethal of known human cancers, with a median survival of less than 15 months. The highly infiltrative nature and genetic heterogeneity of GBM renders treatment difficult. Therefore, better and more targeted therap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::99408bcb4f1f38e37cff60822dd6b62d
https://doi.org/10.1158/1538-7445.am2017-3549
https://doi.org/10.1158/1538-7445.am2017-3549
Autor:
Marianne Hütt-Cabezas, Xing Gang Mao, Lauren Huey, Charles G. Eberhart, Fausto J. Rodriguez, Harpreet Kaur, Eric H. Raabe, Sabeen Zulfiqar Ali, Melanie Weingart, Qian Chu, Isabella Taylor
Glioblastoma (GBM) contains a population of stem-like cells that promote tumor invasion and resistance to therapy. Identifying and targeting stem cell factors in GBM may lead to the development of more effective therapies. High Mobility Group AT-hook
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fea95f8fbbb8f67bc8e2f3b6907ecff7
https://europepmc.org/articles/PMC5091648/
https://europepmc.org/articles/PMC5091648/
Autor:
Sang Hoon Woo, Bryan D. Myers, Sanchita Bhattacharya, Isabella Taylor, Richard A. Lafayette, Geraldine C. Derby
Publikováno v:
Nephrology Research & Reviews. 4:36-41
Individual cytokines have been reported to be associated with the pathogenesis and prognosis of immunoglobulin A (IgA) nephropathy (IgAN). We attempted to characterize a broad cytokine matrix in the serum of patients, and investigate its association
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0373e7ca213fa5a13b7acd8f95469cce
https://doi.org/10.4081/nr.2012.e8
https://doi.org/10.4081/nr.2012.e8
Autor:
Anne M. McIntosh, Samuel F. Berkovic, Ingrid E. Scheffer, Jacinta M McMahon, Isabella Taylor, Danya F. Vears, Bronwyn E. Grinton, Douglas E. Crompton, Penelope A McKelvie, Mark J. Cook, Kate M. Lawrence
Publikováno v:
Brain. 133:3221-3231
Temporal lobe epilepsy is the commonest partial epilepsy of adulthood. Although generally perceived as an acquired disorder, several forms of familial temporal lobe epilepsy, with mesial or lateral seizure semiology, have been described. Descriptions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfd1e344e5deb3fff615190c34549ae8
https://doi.org/10.1093/brain/awq251
https://doi.org/10.1093/brain/awq251
Autor:
Marianne Hütt-Cabezas, Harpreet Kaur, Fausto J. Rodriguez, Charles G. Eberhart, Isabella Taylor, Eric H. Raabe, Melanie Weingart
Diffuse intrinsic pontine glioma (DIPG) and glioblastoma (GBM) are lethal, incurable brain tumors with poor prognosis. Identifying and targeting novel molecular markers regulating tumor invasion and growth can lead to development of better therapies.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::723ee02352e1ea24e55ca34cfd7f41a8
https://europepmc.org/articles/PMC4482981/
https://europepmc.org/articles/PMC4482981/
Autor:
Charles G. Eberhart, Luigi Marchionni, Karisa C. Schreck, Eli E. Bar, William D. Brandt, Eric H. Raabe, Isabella Taylor, Fausto J. Rodriguez
Pilocytic astrocytoma (PA) is the most common primary brain tumor in children; various signaling pathways have been implicated in its biology. The Notch signaling pathway has been found to play a role in the development, stem cell biology, and pathog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df31349cf573bcdac3451c15462e880b
https://europepmc.org/articles/PMC4357229/
https://europepmc.org/articles/PMC4357229/