Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Isabella S. Marchal"'
Autor:
Sudershana Nair, Yixiang Jiang, Isabella S. Marchal, Elizabeth Chernobelsky, Huai-Wei Huang, Sarah Suh, Ruimin Pan, Xiang-Peng Kong, Hyung Don Ryoo, Einar M. Sigurdsson
Publikováno v:
Cell Death and Disease, Vol 15, Iss 7, Pp 1-14 (2024)
Abstract Tauopathies are a group of neurodegenerative diseases characterized by the presence of tau inclusions. We have developed over fifty anti-tau single-domain antibodies (sdAbs) derived from phage display libraries of a llama immunized with reco
Externí odkaz:
https://doaj.org/article/3d4f4ad8cced47af957582702dc480ca
Autor:
Senthilkumar Krishnaswamy, Huai-Wei Huang, Isabella S. Marchal, Hyung Don Ryoo, Einar M. Sigurdsson
Publikováno v:
Neurobiology of Disease, Vol 137, Iss , Pp 104770- (2020)
We have derived single-chain variable fragments (scFv) from tau antibody hybridomas and previously shown their promise as imaging diagnostic agents. Here, we examined the therapeutic potential of anti-tau scFv in transgenic Drosophila models that exp
Externí odkaz:
https://doaj.org/article/3c3086b6121c40059db91f120f12039d
Autor:
Einar M. Sigurdsson, Isabella S. Marchal, Hyung Don Ryoo, Huai-Wei Huang, Senthilkumar Krishnaswamy
Publikováno v:
Neurobiol Dis
Neurobiology of Disease, Vol 137, Iss, Pp 104770-(2020)
Neurobiology of Disease, Vol 137, Iss, Pp 104770-(2020)
We have derived single-chain variable fragments (scFv) from tau antibody hybridomas and previously shown their promise as imaging diagnostic agents. Here, we examined the therapeutic potential of anti-tau scFv in transgenic Drosophila models that exp