Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Isabella M. Salamone"'
Autor:
Isabella M. Salamone, Mattia Quattrocelli, David Y. Barefield, Patrick G. Page, Ibrahim Tahtah, Michele Hadhazy, Garima Tomar, Elizabeth M. McNally
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 6 (2022)
Glucocorticoid steroids are commonly prescribed for many inflammatory conditions, but chronic daily use produces adverse effects, including muscle wasting and weakness. In contrast, shorter glucocorticoid pulses may improve athletic performance, alth
Externí odkaz:
https://doaj.org/article/4f9ec8dcc4bb4c1e9ae34469113326fe
Autor:
Claire C. Oosterbaan, Nina L. Reiser, Michele Hadhazy, Lauren D. Wood, Katherine S. Fallon, Alexis R. Demonbreun, Carl Morris, Elena Bogdanovic, J. Patrick Gonzalez, Mattia Quattrocelli, Isabella M. Salamone, Elizabeth M. McNally, Patrick Page, David Y. Barefield, Matthew P. Velez, Lauren A. Vaught
Publikováno v:
Science Translational Medicine. 13
Duchenne muscular dystrophy, like other muscular dystrophies, is a progressive disorder hallmarked by muscle degeneration, inflammation, and fibrosis. Latent transforming growth factor β (TGFβ) binding protein 4 (LTBP4) is an extracellular matrix p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fbdee06901e8ee3fa2e4eae841c1443
https://doi.org/10.1126/scitranslmed.abf0376
https://doi.org/10.1126/scitranslmed.abf0376
Autor:
Mattia Quattrocelli, Isabella M. Salamone, Elizabeth M. McNally, Aaron S. Zelikovich, Julie A Fischer
Publikováno v:
Journal of Neuromuscular Diseases
Glucocorticoid steroids are widely used as immunomodulatory agents in acute and chronic conditions. Glucocorticoid steroids such as prednisone and deflazacort are recommended for treating Duchenne Muscular Dystrophy where their use prolongs ambulatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d45f368854b1eda467c90f114315597b
https://pubmed.ncbi.nlm.nih.gov/33104035
https://pubmed.ncbi.nlm.nih.gov/33104035
Autor:
Isabella M. Salamone, Tess D. Pottinger, Lorenzo L. Pesce, Laura J. Rasmussen-Torvik, Elizabeth M. McNally, Anthony Gacita, Rex L. Chisholm, Megan J. Puckelwartz, Samuel Kearns, Marcelo A. Nobrega, Maureen E. Smith, Jennifer A. Pacheco
Publikováno v:
Circulation Research. 127
Background: Approximately 6 million adults in the United States have heart failure. The progression of heart failure is variable arising from differences in sex, age, genetic background including ancestry, and medication response. Many population-bas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a412ef12625416bde3358e87500f9df1
https://doi.org/10.1161/res.127.suppl_1.439
https://doi.org/10.1161/res.127.suppl_1.439
Autor:
Elizabeth M. McNally, Samuel Kearns, Megan J. Puckelwartz, Isabella M. Salamone, Rex L. Chisholm, Tess D. Pottinger, Maureen E. Smith, Anthony Gacita, Lindsey E. Montefiori, Jennifer A. Pacheco, Marcelo A. Nobrega, Nathan Hodge, Laura J. Rasmussen-Torvik, Lorenzo L. Pesce
Approximately 6 million adults in the US have heart failure (HF). HF progression is variable due in part to differences in sex, age, and genetic ancestry. Previous population-based genetic studies have largely focused on cross-sectional data related
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79e0d85f5959966cc820f4701d79230d
https://doi.org/10.1101/2020.05.10.087130
https://doi.org/10.1101/2020.05.10.087130
Autor:
Isabella M. Salamone, Patrick Page, Elizabeth M. McNally, Mattia Quattrocelli, Alexis R. Demonbreun, James L. Warner
Publikováno v:
Am J Pathol
The muscular dystrophies are genetically diverse. Shared pathological features among muscular dystrophies include breakdown, or loss of muscle, and accompanying fibrotic replacement. Novel strategies are needed to enhance muscle repair and function a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4aba657fcd0714847e06925b4e22e4e8
https://doi.org/10.1016/j.ajpath.2017.07.017
https://doi.org/10.1016/j.ajpath.2017.07.017
Autor:
Isabella M. Salamone, Danielle M. Maatouk, Christopher R. Futtner, Blanche Capel, Yi-Tzu Lin, S. Alexandra Garcia-Moreno
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 15, Iss 5, p e1007895 (2019)
PLoS Genetics, Vol 15, Iss 5, p e1007895 (2019)
XX and XY fetal gonads are initially bipotential, poised between the ovary and testis fate. Multiple lines of evidence suggest that commitment to testis fate requires the repression of genes associated with ovary fate. It was previously shown that lo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0d06a974a7cadcd15fb7b45268edbc1
http://europepmc.org/articles/PMC6548405
http://europepmc.org/articles/PMC6548405
Autor:
Robin Lovell-Badge, Christopher R. Futtner, Nitzan Gonen, Isabella M. Salamone, S. Alexandra Garcia-Moreno, Danielle M. Maatouk
Cis-regulatory elements are critical for the precise spatiotemporal regulation of genes during development. However, identifying functional regulatory sites that drive cell differentiation in vivo has been complicated by the high numbers of cells req
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fb272f7b93650f100fccf0572b8384e
https://europepmc.org/articles/PMC6368449/
https://europepmc.org/articles/PMC6368449/
Autor:
Danielle M. Maatouk, Francis Poulat, Ryohei Sekido, S. Alexandra Garcia-Moreno, Chris R. Futtner, Nitzan Gonen, Sophie Wood, Isabella M. Salamone, Shiela C. Samson, Robin Lovell-Badge
Publikováno v:
Science
Science, American Association for the Advancement of Science, 2018, 360 (6396), pp.1469-1473. ⟨10.1126/science.aas9408⟩
Science, American Association for the Advancement of Science, 2018, 360 (6396), pp.1469-1473. ⟨10.1126/science.aas9408⟩
Sox9 regulation during sex determination Sex determination is regulated by the Sox9 gene. During testis differentiation, this gene is directly targeted by the product of the Y chromosome–encoded gene Sry . The regulatory region of Sox9 is complex,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fa27d26c5145ad64edd4d5543e1df11
https://hal.archives-ouvertes.fr/hal-01974918
https://hal.archives-ouvertes.fr/hal-01974918
Autor:
S Alexandra Garcia-Moreno, Yi-Tzu Lin, Christopher R Futtner, Isabella M Salamone, Blanche Capel, Danielle M Maatouk
Publikováno v:
PLoS Genetics, Vol 15, Iss 5, p e1007895 (2019)
XX and XY fetal gonads are initially bipotential, poised between the ovary and testis fate. Multiple lines of evidence suggest that commitment to testis fate requires the repression of genes associated with ovary fate. It was previously shown that lo
Externí odkaz:
https://doaj.org/article/db741efa9eb345a094ebfc557ed8fba1