Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Isabella M. Reichardt"'
Autor:
Logan R.J. Bailey, Darrian Bugg, Isabella M. Reichardt, C. Dessirée Ortaç, Jagadambika Gunaje, Richard Johnson, Michael J. MacCoss, Tomoya Sakamoto, Daniel P. Kelly, Michael Regnier, Jennifer M. Davis
Publikováno v:
bioRxiv
Discovering determinants of cardiomyocyte maturity and the maintenance of differentiated states is critical to both understanding development and potentially reawakening endogenous regenerative programs in adult mammalian hearts as a therapeutic stra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::798661f981b32b0da1227afeda653544
https://europepmc.org/articles/PMC10055038/
https://europepmc.org/articles/PMC10055038/
Autor:
Ross C. Bretherton, Isabella M. Reichardt, Kristin A. Zabrecky, Alex J. Goldstein, Logan R.J. Bailey, Darrian Bugg, Timothy S. McMillen, Kristina B. Kooiker, Galina V. Flint, Amy Martinson, Jagdambika Gunaje, Franziska Koser, Elizabeth Plaster, Wolfgang A. Linke, Michael Regnier, Farid Moussavi-Harami, Nathan J. Sniadecki, Cole A. DeForest, Jennifer Davis
Publikováno v:
bioRxiv
Inherited mutations in contractile and structural genes, which decrease cardiomyocyte tension generation, are principal drivers of dilated cardiomyopathy (DCM)– the leading cause of heart failure1,2. Progress towards developing precision therapeuti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29d6d727242a076bceeee75ea3108274
https://europepmc.org/articles/PMC9900749/
https://europepmc.org/articles/PMC9900749/
Autor:
Darrian Bugg, Logan R.J. Bailey, Ross C. Bretherton, Kylie E. Beach, Isabella M. Reichardt, Kalen Z. Robeson, Anna C. Reese, Jagadambika Gunaje, Galina Flint, Cole A. DeForest, April Stempien-Otero, Jennifer Davis
Publikováno v:
Cell Stem Cell
Dynamic fibroblast to myofibroblast state transitions underlie the heart's fibrotic response. Because transcriptome maturation by muscleblind-like 1 (MBNL1) promotes differentiated cell states, this study investigated whether tactical control of MBNL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99c7d34019387b957fcbc8679f717919
https://europepmc.org/articles/PMC8929295/
https://europepmc.org/articles/PMC8929295/
Autor:
Alexandra B. Steinberg, Martha E. Floy, Isabella M. Reichardt, Sean P. Palecek, Kaitlin K. Dunn, Taylor D. Mateyka
Publikováno v:
J Mol Cell Cardiol
Epicardial cells (EpiCs) are necessary for myocardium formation, yet little is known about crosstalk between EpiCs and cardiomyocytes (CMs) during development and the potential impact of EpiCs on CM maturation. To investigate the effects of EpiCs on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b64fcce434052b78c905ba176745954
https://europepmc.org/articles/PMC8766908/
https://europepmc.org/articles/PMC8766908/
Autor:
Kelsey M. Hoon, Isabella M. Reichardt, Aaron D. Simmons, Martha E. Floy, Sean P. Palecek, Kaitlin K. Dunn, Gyuhyung Jin
Publikováno v:
Biotechnology Journal. 14:1800725
Cardiomyocytes (CMs) generated from human pluripotent stem cells (hPSCs) are immature in their structure and function, limiting their potential in disease modeling, drug screening, and cardiac cellular therapies. Prior studies have demonstrated that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f74d29d0392ffe1baac6f2d90b9ae81
https://doi.org/10.1002/biot.201800725
https://doi.org/10.1002/biot.201800725
