Zobrazeno 1 - 10
of 102
pro vyhledávání: '"Isabella M Grumbach"'
Autor:
Chu-Yu Lee, Daniel R. Thedens, Olivia Lullmann, Emily J. Steinbach, Michelle R. Tamplin, Michael S. Petronek, Isabella M. Grumbach, Bryan G. Allen, Lyndsay A. Harshman, Vincent A. Magnotta
Publikováno v:
Tomography, Vol 10, Iss 7, Pp 1074-1088 (2024)
The MR transverse relaxation rate, R2*, has been widely used to detect iron and myelin content in tissue. However, it is also sensitive to macroscopic B0 inhomogeneities. One approach to correct for the B0 effect is to fit gradient-echo signals with
Externí odkaz:
https://doaj.org/article/6da44ec3a8c1419c9d350f4b81318e7f
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0190549 (2018)
An improved method for detecting coronary heart disease (CHD) could have substantial clinical impact. Building on the idea that systemic effects of CHD risk factors are a conglomeration of genetic and environmental factors, we use machine learning te
Externí odkaz:
https://doaj.org/article/d5a310f9b34f44899f58689bb1ec5289
Autor:
Shubha Murthy, Olha M Koval, Juan M Ramiro Diaz, Santosh Kumar, Daniel Nuno, Jason A Scott, Chantal Allamargot, Linda J Zhu, Kim Broadhurst, Velarchana Santhana, William J Kutschke, Kaikobad Irani, Kathryn G Lamping, Isabella M Grumbach
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0186311 (2017)
The multifunctional Ca2+/calmodulin-dependent protein kinase II (CaMKII) is a serine/threonine kinase important in transducing intracellular Ca2+ signals. While in vitro data regarding the role of CaMKII in the regulation of endothelial nitric oxide
Externí odkaz:
https://doaj.org/article/f354a460347249199e1fb8733db21214
Autor:
Karima Ait‐Aissa, Xutong Guo, Madelyn Klemmensen, Denise Juhr, Linette N. Leng, Olha M. Koval, Isabella M. Grumbach
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 13 (2024)
Background The incidental use of statins during radiation therapy has been associated with a reduced long‐term risk of developing atherosclerotic cardiovascular disease. We examined whether irradiation causes chronic vascular injury and whether sho
Externí odkaz:
https://doaj.org/article/8ecab4d33c914653aba01a3b3976518b
Autor:
Michelle R. Tamplin, Jui-Kai Wang, Elaine M. Binkley, Mona K. Garvin, Daniel E. Hyer, John M. Buatti, H. Culver Boldt, Isabella M. Grumbach, Randy H. Kardon
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Optical coherence tomography (OCT) has become a key method for diagnosing and staging radiation retinopathy, based mainly on the presence of fluid in the central macula. A robust retinal layer segmentation method is required for identificati
Externí odkaz:
https://doaj.org/article/ead76d9605be40399f25c5ad2f397633
Autor:
Jason A Scott, Paula J Klutho, Ramzi El Accaoui, Emily Nguyen, Ashlee N Venema, Litao Xie, Shuxia Jiang, Megan Dibbern, Sabrina Scroggins, Anand M Prasad, Elisabeth D Luczak, Melissa K Davis, Weiwei Li, Xiaoqun Guan, Johannes Backs, Annette J Schlueter, Robert M Weiss, Francis J Miller, Mark E Anderson, Isabella M Grumbach
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e71550 (2013)
OBJECTIVE:Sustained hemodynamic stress mediated by high blood flow promotes arteriogenesis, the outward remodeling of existing arteries. Here, we examined whether Ca²⁺/calmodulin-dependent kinase II (CaMKII) regulates arteriogenesis. METHODS AND R
Externí odkaz:
https://doaj.org/article/a6212747293a4b058e5501de611d149f
Autor:
Karima Ait-Aissa, Linette N. Leng, Nathanial R. Lindsey, Xutong Guo, Denise Juhr, Olha M. Koval, Isabella M. Grumbach
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
BackgroundThe incidental use of statins during radiation therapy has been associated with a reduced long-term risk of developing atherosclerotic cardiovascular disease. However, the mechanisms by which statins protect the vasculature from irradiation
Externí odkaz:
https://doaj.org/article/6d4ac833de5f423784e93beaf04e6f78
Autor:
Michelle R. Tamplin, Jui-Kai Wang, Anthony H. Vitale, Ryuya Hashimoto, Mona K. Garvin, Elaine M. Binkley, Daniel E. Hyer, John M. Buatti, H. Culver Boldt, Randy H. Kardon, Isabella M. Grumbach
Publikováno v:
BMC Ophthalmology, Vol 22, Iss 1, Pp 1-11 (2022)
Abstract Background To determine whether reductions in retinal and choroidal blood flow measured by laser speckle flowgraphy are detected after 125I-plaque brachytherapy for uveal melanoma. Methods In a cross-sectional study, retinal and choroidal bl
Externí odkaz:
https://doaj.org/article/35b2bde7617b48a6aabefe58e82ac325
Autor:
Olha M. Koval, Emily K. Nguyen, Dylan J. Mittauer, Karima Ait-Aissa, William C. Chinchankar, Isabella M. Grumbach
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 16, p 12897 (2023)
Type 2 diabetes (T2D) is associated with increased risk of atherosclerotic vascular disease due to excessive vascular smooth muscle cell (VSMC) proliferation. Here, we investigated the role of mitochondrial dysfunction and Ca2+ levels in VSMC prolife
Externí odkaz:
https://doaj.org/article/029ee44280c94cdbb8a60648414928d8
Autor:
Elaine M. Binkley, Michelle R. Tamplin, Anthony H. Vitale, H. Culver Boldt, Randy H. Kardon, Isabella M. Grumbach
Publikováno v:
American Journal of Ophthalmology Case Reports, Vol 26, Iss , Pp 101508- (2022)
Purpose: Patients with choroidal melanoma treated with brachytherapy lose vision over time due to radiation retinopathy and optic neuropathy. Newer imaging modalities such as optical coherence tomography angiography (OCT-A) may provide further insigh
Externí odkaz:
https://doaj.org/article/f729ceb5fc704f9bb2704a033370d86c