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pro vyhledávání: '"Isabella Lubin"'
Autor:
Daniel J Chiu, R. Mako Saito, Barbara Conradt, Laura D Young, Joseph E. Clayton, Nadin Memar, Sarah H. Roy, Eleanor M. Beltz, Jenna Holmen, Travis H Green, Isabella Lubin, David V. Tobin, Yuying Liu
Publikováno v:
G3: Genes|Genomes|Genetics
The development and homeostasis of multicellular animals requires precise coordination of cell division and differentiation. We performed a genome-wide RNA interference screen in Caenorhabditis elegans to reveal the components of a regulatory network
Publikováno v:
Monash University
SummaryTRIM-NHL proteins represent a large class of metazoan proteins implicated in development and disease. We demonstrate that a C. elegans TRIM-NHL protein, NHL-2, functions as a cofactor for the microRNA-induced silencing complex (miRISC) and the