Zobrazeno 1 - 8 of 8 pro vyhledávání: '"Isabella Inzani"'
1
Akademický článek
Coordinated changes in gene expression kinetics underlie both mouse and human erythroid maturation
Autor: Melania Barile, Ivan Imaz-Rosshandler, Isabella Inzani, Shila Ghazanfar, Jennifer Nichols, John C. Marioni, Carolina Guibentif, Berthold Göttgens
Publikováno v: Genome Biology, Vol 22, Iss 1, Pp 1-22 (2021)
Abstract Background Single-cell technologies are transforming biomedical research, including the recent demonstration that unspliced pre-mRNA present in single-cell RNA-Seq permits prediction of future expression states. Here we apply this RNA veloci
Externí odkaz: https://doaj.org/article/612c8ca067714602822b1e9460b4c3c2
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2
Akademický článek
Maternal diet-induced obesity during pregnancy alters lipid supply to mouse E18.5 fetuses and changes the cardiac tissue lipidome in a sex-dependent manner
Autor: Lucas C Pantaleão, Isabella Inzani, Samuel Furse, Elena Loche, Antonia Hufnagel, Thomas Ashmore, Heather L Blackmore, Benjamin Jenkins, Asha A M Carpenter, Ania Wilczynska, Martin Bushell, Albert Koulman, Denise S Fernandez-Twinn, Susan E Ozanne
Publikováno v: eLife, Vol 11 (2022)
Maternal obesity during pregnancy has immediate and long-term detrimental effects on the offspring heart. In this study, we characterized the cardiac and circulatory lipid profiles in late gestation E18.5 fetuses of diet-induced obese pregnant mice a
Externí odkaz: https://doaj.org/article/a87a0340baca416d87bef9384d650677
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3
Programming by maternal obesity: a pathway to poor cardiometabolic health in the offspring
Autor: Isabella Inzani, Susan E. Ozanne
Publikováno v: Proc Nutr Soc
There is an ever increasing prevalence of maternal obesity worldwide such that in many populations over half of women enter pregnancy either overweight or obese. This review aims to summarise the impact of maternal obesity on offspring cardiometaboli
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6d913ce10a5be6fed7fb78399cc2b4c
https://www.repository.cam.ac.uk/handle/1810/340358
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4
Thyroid Hormone Deficiency Suppresses Fetal Pituitary–Adrenal Function Near Term: Implications for the Control of Fetal Maturation and Parturition
Autor: F. B. Peter Wooding, Dominique Blache, Abigail L. Fowden, Alison J. Forhead, Emily J. Camm, Isabella Inzani, Katie L. Davies, India R. Lloyd, Miles J. De Blasio
Publikováno v: Thyroid. 31:861-869
Background: The fetal hypothalamic–pituitary–adrenal (HPA) axis plays a key role in the control of parturition and maturation of organ systems in preparation for birth. In hypothyroid fetuses, gest...
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed9cc63e25e3aafeedbd26055f83c70b
https://doi.org/10.1089/thy.2020.0534
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5
Maternal diet-induced obesity during pregnancy alters lipid supply to mouse E18.5 fetuses and changes the cardiac tissue lipidome in a sex- dependent manner
Autor: Isabella Inzani, Lucas C Pantaleão, Samuel Furse, Elena Loche, Antonia Hufnagel, Thomas Ashmore, Heather L Blackmore, Benjamin Jenkins, Asha A M Carpenter, Ania Wilczynska, Martin Bushell, Albert Koulman, Denise S Fernandez-Twinn, Susan E Ozanne
Publikováno v: eLife, Vol 11 (2022)
eLife
Maternal obesity during pregnancy has immediate and long-term detrimental effects on the offspring heart. In this study, we characterized the cardiac and circulatory lipid profiles in late gestation E18.5 fetuses of diet-induced obese pregnant mice a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37c2e06ab2948bdf84a7fd26e7386ba9
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