Zobrazeno 1 - 10 of 40 pro vyhledávání: '"Isabella Gnemmi"'
1
Akademický článek
Impaired autophagy in the lower airways and lung parenchyma in stable COPD
Autor: Stefano Levra, Umberto Rosani, Isabella Gnemmi, Paola Brun, Andrea Leonardi, Vitina Carriero, Francesca Bertolini, Bruno Balbi, Mirella Profita, Fabio Luigi Massimo Ricciardolo, Antonino Di Stefano
Publikováno v: ERJ Open Research, Vol 9, Iss 6 (2023)
Background There is increasing evidence of autophagy activation in COPD, but its role is complex and probably regulated through cell type-specific mechanisms. This study aims to investigate the autophagic process at multiple levels within the respira
Externí odkaz: https://doaj.org/article/668239dd6839401d9ae5446a00c7cf1f
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2
Akademický článek
Decreased humoral immune response in the bronchi of rapid decliners with chronic obstructive pulmonary disease
Autor: Antonino Di Stefano, Francesca Dossena, Isabella Gnemmi, Silvestro Ennio D’Anna, Paola Brun, Bruno Balbi, Alessio Piraino, Antonio Spanevello, Francesco Nucera, Vitina Carriero, Francesca Bertolini, Mauro Maniscalco, Ian M. Adcock, Gaetano Caramori, Fabio L. M. Ricciardolo
Publikováno v: Respiratory Research, Vol 23, Iss 1, Pp 1-13 (2022)
Abstract Background Identification of COPD patients with a rapid decline in FEV1 is of particular interest for prognostic and therapeutic reasons. Objective To determine the expression of markers of inflammation in COPD patients with rapid functional
Externí odkaz: https://doaj.org/article/99e754ddc55e464b92dedc9b4ae49c18
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3
Akademický článek
Bone Morphogenic Proteins and Their Antagonists in the Lower Airways of Stable COPD Patients
Autor: Antonino Di Stefano, Umberto Rosani, Stefano Levra, Isabella Gnemmi, Paola Brun, Mauro Maniscalco, Silvestro Ennio D’Anna, Vitina Carriero, Francesca Bertolini, Fabio L. M. Ricciardolo
Publikováno v: Biology, Vol 12, Iss 10, p 1304 (2023)
Background: Bone morphogenic proteins (BMPs) and their antagonists are involved in the tissue development and homeostasis of various organs. Objective: To determine transcriptomic and protein expression of BMPs and their antagonists in stable COPD. M
Externí odkaz: https://doaj.org/article/5d4e9ec31ecd41559bfd393d5b1760be
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4
Akademický článek
Extracorporeal Shock Waves Increase Markers of Cellular Proliferation in Bronchial Epithelium and in Primary Bronchial Fibroblasts of COPD Patients
Autor: Antonino Di Stefano, Roberto Frairia, Fabio L. M. Ricciardolo, Isabella Gnemmi, Antonella Marino Gammazza, Alessio Piraino, Francesco Cappello, Bruno Balbi, Maria Graziella Catalano
Publikováno v: Canadian Respiratory Journal, Vol 2020 (2020)
Chronic obstructive pulmonary disease (COPD) is due to structural changes and narrowing of small airways and parenchymal destruction (loss of the alveolar attachment as a result of pulmonary emphysema), which all lead to airflow limitation. Extracorp
Externí odkaz: https://doaj.org/article/18b29c4aeec04190a8fe1084c3c89b3b
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5
Akademický článek
Convergent sets of data from in vivo and in vitro methods point to an active role of Hsp60 in chronic obstructive pulmonary disease pathogenesis.
Autor: Francesco Cappello, Gaetano Caramori, Claudia Campanella, Chiara Vicari, Isabella Gnemmi, Andrea Zanini, Antonio Spanevello, Armando Capelli, Giampiero La Rocca, Rita Anzalone, Fabio Bucchieri, Silvestro Ennio D'Anna, Fabio L M Ricciardolo, Paola Brun, Bruno Balbi, Mauro Carone, Giovanni Zummo, Everly Conway de Macario, Alberto J L Macario, Antonino Di Stefano
Publikováno v: PLoS ONE, Vol 6, Iss 11, p e28200 (2011)
BackgroundIt is increasingly clear that some heat shock proteins (Hsps) play a role in inflammation. Here, we report results showing participation of Hsp60 in the pathogenesis of chronic obstructive pulmonary diseases (COPD), as indicated by data fro
Externí odkaz: https://doaj.org/article/17adeac62af342d3ae37bd8812d2dade
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7
Pathogenesis of COPD at the cellular and molecular level
Autor: Antonino DI STEFANO, Isabella GNEMMI, Francesca DOSSENA, Fabio L. RICCIARDOLO, Mauro MANISCALCO, Federica LO BELLO, Bruno BALBI
Chronic inflammatory responses in the lung of patients with stable mild-to-severe forms of chronic obstructive pulmonary disease (COPD) play a central role in the definition, comprehension and monitoring of the disease state. A better understanding o
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32f498b0115229cf476f8e33a023e0d0
http://hdl.handle.net/11588/891668
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8
Bacterial load and inflammatory response in sputum of alpha-1 antitrypsin deficiency patients with COPD
Autor: Fabio Lm Ricciardolo, Gaetano Caramori, Davide Vallese, Lorena Delle Donne, Ilaria Ferrarotti, Francesco Cappello, Angelo Corsico, Mauro Carone, Bruno Balbi, Elena Paracchini, Paola Brun, Ian M. Adcock, Isabella Gnemmi, Antonino Di Stefano, Paolo Baderna, Luciano Corda, Sharon Mumby, Claudia Sangiorgi, Paolo Ruggeri
Publikováno v: International Journal of Chronic Obstructive Pulmonary Disease. 14:1879-1893
Background Airway inflammation may drive the progression of chronic obstructive pulmonary disease (COPD) associated with alpha-1 antitrypsin deficiency (AATD), but the relationship between airway microbiota and inflammation has not been investigated.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8f293a07cb1a59873027798e527a4a26
https://doi.org/10.2147/copd.s207203
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9
Impact of Galectin-3 Circulating Levels on Frailty in Elderly Patients with Systolic Heart Failure
Autor: Klara Komici, Dino Franco Vitale, Leonardo Bencivenga, Giuseppe Rengo, Isabella Gnemmi, Antonino Di Stefano, Ermanno Eleuteri
Publikováno v: Journal of Clinical Medicine, Vol 9, Iss 2229, p 2229 (2020)
Journal of Clinical Medicine
Volume 9
Issue 7
Background: Heart Failure (HF), a leading cause of morbidity and mortality, represents a relevant trigger for the development of frailty in the elderly. Inflammation has been reported to play an important role in HF and frailty pathophysiology. Galec
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c0aa6921095fa33b7982ef8de832d8c
https://www.mdpi.com/2077-0383/9/7/2229
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10
Extracorporeal Shock Waves Increase Markers of Cellular Proliferation in Bronchial Epithelium and in Primary Bronchial Fibroblasts of COPD Patients
Autor: Antonella Marino Gammazza, Bruno Balbi, Alessio Piraino, Francesco Cappello, Roberto Frairia, Fabio Luigi Massimo Ricciardolo, Maria Graziella Catalano, Isabella Gnemmi, Antonino Di Stefano
Publikováno v: Canadian respiratory journal, 2020:1524716
Canadian Respiratory Journal
Canadian Respiratory Journal, Vol 2020 (2020)
Chronic obstructive pulmonary disease (COPD) is due to structural changes and narrowing of small airways and parenchymal destruction (loss of the alveolar attachment as a result of pulmonary emphysema), which all lead to airflow limitation. Extracorp
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da4802588345c65956346ec1e3554d7e
http://hdl.handle.net/10447/457178
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