Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Isabella Faraoni"'
Autor:
Manuela Giansanti, Tiziana Ottone, Serena Travaglini, Maria Teresa Voso, Grazia Graziani, Isabella Faraoni
Publikováno v:
Pharmaceuticals, Vol 17, Iss 11, p 1529 (2024)
Background: Arsenic trioxide (ATO) is an anticancer agent for treating acute promyelocytic leukemia (APL). However, 5–10% of patients fail to respond, developing relapsed/refractory disease. The aim of this study was to identify potential new thera
Externí odkaz:
https://doaj.org/article/2644cd1886e3415fb05146a7b5b15068
Autor:
Tiziana Ottone, Isabella Faraoni, Giorgio Fucci, Mariadomenica Divona, Serena Travaglini, Eleonora De Bellis, Francesco Marchesi, Daniela Francesca Angelini, Raffaele Palmieri, Carmelo Gurnari, Manuela Giansanti, Anna Maria Nardozza, Federica Montesano, Emiliano Fabiani, Elisa Linnea Lindfors Rossi, Raffaella Cerretti, Laura Cicconi, Marco De Bardi, Maria Luisa Catanoso, Luca Battistini, Renato Massoud, Adriano Venditti, Maria Teresa Voso
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Vitamin C has been shown to play a significant role in suppressing progression of leukemia through epigenetic mechanisms. We aimed to study the role of vitamin C in acute myeloid leukemia (AML) biology and clinical course. To this purpose, the plasma
Externí odkaz:
https://doaj.org/article/3addc2e8b97f4c029ccc1a66b6cbd388
Publikováno v:
European Journal of Clinical Microbiology & Infectious Diseases
Receptor recognition is a crucial step in viral infection and is a critical factor for cell entry and tissue tropism. In several recent studies, angiotensin-converting enzyme 2 (ACE2) has been demonstrated to be the cellular receptor of SARS-CoV-2 as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::333281aa8cc701004be72d4cbb7e8add
https://doi.org/10.1007/s10096-021-04264-9
https://doi.org/10.1007/s10096-021-04264-9
Autor:
Grazia Graziani, Maria Domenica Divona, Maria Teresa Voso, Antonio De Gabrieli, Fabio Ciccarone, Manuela Giansanti, Isabella Faraoni, Terry Karimi, Tiziana Ottone, S.P. Prete
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 377:385-397
Arsenic trioxide (ATO) is an anticancer agent used for the treatment ofacute promyelocytic leukemia (APL). However, 5%–10% of patients fail to respond or experience disease relapse. Based on poly(ADP-ribose) polymerase (PARP) 1 involvement in the p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d70d45cf8fcccb1778f3412948705d2f
https://doi.org/10.1124/jpet.121.000537
https://doi.org/10.1124/jpet.121.000537
Autor:
Ornella Franzese, Francesco Torino, Angelo Aquino, Enzo Bonmassar, Bernd Kaina, Elisa Giannetti, Isabella Faraoni, Anna Giuliani, Maria Pia Fuggetta, Giorgia Cioccoloni, Liana De Vecchis
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 10672, p 10672 (2021)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
The current state of cancer treatment is still far from being satisfactory considering the strong impairment of patients’ quality of life and the high lethality of malignant diseases. Therefore, it is critical for innovative approaches to be tested
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::403c48b99579215d119254ebd6953be1
https://eprints.whiterose.ac.uk/179906/1/ijms-22-10672-v2.pdf
https://eprints.whiterose.ac.uk/179906/1/ijms-22-10672-v2.pdf
Ellagic acid (EA) is a polyphenolic compound whose dietary consumption is mainly associated with the intake of red fruits, including pomegranates, strawberries, blackberries, blackcurrants, raspberries, grapes or dried fruits, like walnuts and almond
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ca021c0cf867d10e3cfc43a3a6a49d3
http://hdl.handle.net/2108/256603
http://hdl.handle.net/2108/256603
Autor:
Paola Grimaldi, Grazia Graziani, Giovanna D'Arcangelo, Emanuela De Domenico, Lucio Tentori, Mattia Palmieri, Isabella Faraoni, Virginia Tancredi
Publikováno v:
Oncotarget
The Growth Differentiation Factor 11 (GDF11) has been controversially involved in the aging/rejuvenation process. To clarify whether GDF11 is differently expressed during aging, we have evaluated GDF11 levels in skeletal muscles and hippocampi of you
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba5fc6be3fdb79ba6c98c5501f7b7e0a
https://doi.org/10.18632/oncotarget.19854
https://doi.org/10.18632/oncotarget.19854
Autor:
Mariadomenica Divona, Nélida I. Noguera, Gianfranco Catalano, Isabella Faraoni, Tiziana Ottone, Cristina Banella, Maria Teresa Voso, William Arcese
Publikováno v:
Cancers, Vol 11, Iss 10, p 1591 (2019)
Cancers
Cancers
This review highlights new findings that have deepened our understanding of the mechanisms of leukemogenesis, therapy and resistance in acute promyelocytic leukemia (APL). Promyelocytic leukemia-retinoic acid receptor α (PML-RARa) sets the cellular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c98826f07947132529342463e56abe8
https://doi.org/10.20944/preprints201910.0159.v1
https://doi.org/10.20944/preprints201910.0159.v1
Publikováno v:
Biochemical pharmacology. 167
Acute myeloid leukaemia (AML) is a highly heterogeneous disease characterized by uncontrolled proliferation, block in myeloid differentiation and recurrent genetic abnormalities. In the search of new effective therapies, identification of synthetic l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91df6cb24ec37dd05fe43ee1aae13305
https://pubmed.ncbi.nlm.nih.gov/31028744
https://pubmed.ncbi.nlm.nih.gov/31028744
Autor:
Manuela Zonfrillo, Angelo Aquino, Maria Notarnicola, Isabella Faraoni, Simona Caporali, Maria Pia Fuggetta, Ornella Franzese, Maria Gabriella Caruso, Cristina Villivà, Giorgia Cioccoloni, Enzo Bonmassar
Fatty Acid Synthase (FASN) is responsible for the de novo synthesis of fatty acids, which are involved in the preservation of biological membrane structure, energy storage and assembly of factors involved in signal transduction. FASN plays a critical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9600b56befcdc35885f8c2dffc9217e6