Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Isabella E. Maudlin"'
Publikováno v:
RNA Biology, Vol 16, Iss 12, Pp 1775-1784 (2024)
Pre-messenger RNA splicing involves multi-step assembly of the large spliceosome complexes that catalyse the two consecutive trans-esterification reactions, resulting in intron removal. There is evidence that proof-reading mechanisms monitor the fide
Externí odkaz:
https://doaj.org/article/fe41cc9df50f45d7853c0dfdf966cbe4
Autor:
Isabella E. Maudlin, Jean D. Beggs
Publikováno v:
RNA Biology
article-version (VoR) Version of Record
article-version (VoR) Version of Record
From yeast to humans, pre-mRNA splicing occurs mainly co-transcriptionally, with splicing and transcription functionally coupled such that they influence one another. The recruitment model of co-transcriptional splicing proposes that core members of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b4dbc409db442bfa2ef63d422b6baea
https://doi.org/10.1080/15476286.2021.1991673
https://doi.org/10.1080/15476286.2021.1991673
Publikováno v:
Mendoza ochoa, G, Barrass, J, Maudlin, I & Beggs, J 2019, ' Blocking late stages of splicing quickly limits pre-spliceosome assembly in vivo ', Rna biology . https://doi.org/10.1080/15476286.2019.1657788
RNA Biology
RNA Biology
Pre-messenger RNA splicing involves multi-step assembly of the large spliceosome complexes that catalyse the two consecutive trans-esterification reactions, resulting in intron removal. There is evidence that proof-reading mechanisms monitor the fide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04713d11e26e323785483db0b2b76b7c
https://doi.org/10.1080/15476286.2019.1657788
https://doi.org/10.1080/15476286.2019.1657788
Autor:
J David, Barrass, Gonzalo I, Mendoza-Ochoa, Isabella E, Maudlin, Emanuela, Sani, Jean D, Beggs
Publikováno v:
Journal of visualized experiments : JoVE. (149)
The plant auxin binding receptor, TIR1, recognizes proteins containing a specific auxin-inducible degron (AID) motif in the presence of auxin, targeting them for degradation. This system is exploited in many non-plant eukaryotes, such that a target p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4fe5a677d51be6c5bc9a293fc4fb59b9
https://pubmed.ncbi.nlm.nih.gov/31380835
https://pubmed.ncbi.nlm.nih.gov/31380835
Autor:
Isabella E, Maudlin, Jean D, Beggs
Publikováno v:
RNA (New York, N.Y.). 25(10)
There is increasing evidence from yeast to humans that pre-mRNA splicing occurs mainly cotranscriptionally, such that splicing and transcription are functionally coupled. Currently, there is little insight into the contribution of the core transcript
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::47f10da602f9ca591b644538dacb106b
https://pubmed.ncbi.nlm.nih.gov/31289129
https://pubmed.ncbi.nlm.nih.gov/31289129
Publikováno v:
Molecular and Biochemical Parasitology
Highlights • VSG mRNA copy number varies with the identity of the VSG. • Early premature termination codons result in degradation of VSG mRNA. • Late premature termination codons translated to produce incomplete VSG result in an increase in VSG
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::563873775ef832a609890887cc6d2dd4
https://doi.org/10.1016/j.molbiopara.2020.111348
https://doi.org/10.1016/j.molbiopara.2020.111348
Publikováno v:
Chromosome Research
Molina, O, Carmena, M, Maudlin, I E & Earnshaw, W C 2016, ' PREditOR: A synthetic biology approach to removing heterochromatin from cells ', Chromosome Research, vol. 24, no. 4, pp. 495-509 . https://doi.org/10.1007/s10577-016-9539-3
Molina, O, Carmena, M, Maudlin, I E & Earnshaw, W C 2016, ' PREditOR: A synthetic biology approach to removing heterochromatin from cells ', Chromosome Research, vol. 24, no. 4, pp. 495-509 . https://doi.org/10.1007/s10577-016-9539-3
It is widely accepted that heterochromatin is necessary to maintain genomic stability. However, direct experimental evidence supporting this is slim. Previous studies using either enzyme inhibitors, gene knockout or knockdown studies all are subject
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f98d55e77fbd9a9ef678c2f54a9c8ac0
https://pubmed.ncbi.nlm.nih.gov/27924426
https://pubmed.ncbi.nlm.nih.gov/27924426