Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Isabella Dell'Aica"'
Autor:
Spiridione Garbisa, Ilaria Sogno, Elena Araldi, Girieca Lorusso, Adriana Albini, Isabella Dell'Aica
Publikováno v:
Current Cancer Drug Targets. 8:146-155
Prostate cancer is the most common cancer in men and one of the leading causes of cancer-related deaths in Western countries. The extraordinary biological heterogeneity, the increasing incidence of this disease, and the presence of putative premalign
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::899d59ba1527d7e26745043d777898bc
https://doi.org/10.2174/156800908783769382
https://doi.org/10.2174/156800908783769382
Publikováno v:
Current Bioactive Compounds. 3:109-119
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64eb47a91106d867e638851ae2d87582
https://doi.org/10.2174/157340707780809644
https://doi.org/10.2174/157340707780809644
Autor:
Roberto Benelli, Spiridione Garbisa, Fiorella Calabrese, Anna Cabrelle, Adriana Albini, Raffaele Niero, Isabella Dell'Aica, Luigi Sartor, Enrico Brunetta, Cristiano Colalto, Carlo Agostini, Girieca Lorusso, Francesco Piazza
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 321:492-500
Hyperforin (Hyp), a polyphenol-derivative of St. John9s wort ( Hypericum perforatum ), has emerged as key player not only in the antidepressant activity of the plant but also as an inhibitor of bacteria lymphocyte and tumor cell proliferation, and ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbbd3386f354de55635ef490ca0a3066
https://doi.org/10.1124/jpet.106.116459
https://doi.org/10.1124/jpet.106.116459
Autor:
Isabella Dell'Aica, Arianna Quintavalla, Cinzia Giacometti, Daria Giacomini, Fiorella Calabrese, Paola Galletti, Francesco Piazza, Spiridione Garbisa, Luigi Sartor, Carlo Agostini, Enrico Brunetta
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 316:539-546
beta-Lactams, a well known class of antibiotics, have been investigated as inhibitors of the disruptive protease released by inflammatory cells, leukocyte elastase (LE). We have synthesized a new beta-lactam with an N-linked galloyl moiety, the latte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2eb7ad6c71722b876cafcd3deb878bb0
https://doi.org/10.1124/jpet.105.096248
https://doi.org/10.1124/jpet.105.096248
Autor:
Fiorella Calabrese, Monica Morini, Massimo Donà, Spiridione Garbisa, Isabella Dell'Aica, Elga Pezzato, Luigi Sartor, Adriana Albini
Publikováno v:
International Journal of Cancer. 112:823-829
Green tea infusion has been shown to inhibit metastatic spreading of the transgenic adenocarcinoma of mouse prostate (TRAMP). Investigation on the molecular mechanisms triggered by the main green tea flavonoid, (-)epigallocatechin-3-gallate (EGCG), s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::426c14f4d900eee2960e7ae8105d4c2c
https://doi.org/10.1002/ijc.20496
https://doi.org/10.1002/ijc.20496
Autor:
Elga Pezzato, Luigi Sartor, Isabella Dell'Aica, Rosamaria Caniato, Susan Biggin, Spiridione Garbisa
Publikováno v:
Biochemical Pharmacology. 64:229-237
Flavanols—a class of plant polyphenols abundant in tea leaves and grape seeds and skins—have been found to inhibit some matrix-proteases instrumental in inflammation and cancer invasion, such as leukocyte elastase (LE) and gelatinases. In order t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc419af68f80ad10e2429d7ed76ad720
https://doi.org/10.1016/s0006-2952(02)01069-9
https://doi.org/10.1016/s0006-2952(02)01069-9
Autor:
Elisa Scquizzato, G. D’Intino, Samuela Carraro, Spiridione Garbisa, Enrico Brunetta, Raffaele Niero, Luca Melchiori, Isabella Dell'Aica, Laura Calzà, Anna Cabrelle, Carlo Agostini
Publikováno v:
Journal of leukocyte biology. 83(1)
Hyperforin (Hyp) is an active compound contained in the extract of Hypericum perforatum, well known for its antidepressant activity. However, Hyp has been found to possess several other biological properties, including inhibitory effects on tumor inv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44b46010b5466bf1b37c84e71b0e5511
https://pubmed.ncbi.nlm.nih.gov/17947392
https://pubmed.ncbi.nlm.nih.gov/17947392
Background Some proteases involved in extracellular matrix degradation are instrumental not only in overcoming tissue barriers to allow normal extravasation of hematic cells, but also in facilitating pathological processes such as inflammation, angio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0a4e2d8eb41126b285e0338a3300668
http://hdl.handle.net/11577/2447697
http://hdl.handle.net/11577/2447697
This review does not presume to be exhaustive in the field of leukocyte elastase inhibitors. Instead, a general picture will be sketched to give the reader a brief update and encourage advances in this continuously growing sector of pharmacology, dru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8971ac4f04749d155e7e6558cb79ec85
http://hdl.handle.net/11577/2447246
http://hdl.handle.net/11577/2447246
Autor:
Isabella Dell'Aica, Elga Pezzato, Claudio Belluco, Spiridione Garbisa, Massimo Gion, Mario Lise, Ruggero Dittadi, Luigi Sartor
Publikováno v:
International journal of cancer. 112(5)
Prostate-specific antigen (PSA) is a serine-protease that, in addition to cleaving semenogelins in the seminal coagulum, is able to cleave extracellular matrix glycoproteins, thereby affecting cell migration and metastasis. We here report some new ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23aa542c84648a432fa65900c446ce2c
https://pubmed.ncbi.nlm.nih.gov/15386386
https://pubmed.ncbi.nlm.nih.gov/15386386