Zobrazeno 1 - 10
of 156
pro vyhledávání: '"Isabella Dalle‐Donne"'
Autor:
Francesca Bianchi, Valentino Le Noci, Giancarla Bernardo, Nicoletta Gagliano, Graziano Colombo, Michele Sommariva, Michele Palazzo, Isabella Dalle-Donne, Aldo Milzani, Serenella Pupa, Elda Tagliabue, Lucia Sfondrini
Publikováno v:
PLoS ONE, Vol 19, Iss 5, p e0303875 (2024)
BackgroundIt is amply demonstrated that cigarette smoke (CS) has a high impact on lung tumor progression worsening lung cancer patient prognosis and response to therapies. Alteration of immune cell types and functions in smokers' lungs have been stri
Externí odkaz:
https://doaj.org/article/8a2624a1ac2f4373a6306a1b2b1d3daf
Autor:
Elisa Moschini, Graziano Colombo, Giuseppe Chirico, Giancarlo Capitani, Isabella Dalle-Donne, Paride Mantecca
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-18 (2023)
Abstract It is well known that copper oxide nanoparticles (CuO NPs) are heavily toxic on in vitro systems. In human alveolar epithelial cells, the mechanism of toxicity is mostly related to oxidative insults, coming from intracellularly dissolved cop
Externí odkaz:
https://doaj.org/article/6e274aa8a7034737a3169063265d5a82
Autor:
Maria Lisa Garavaglia, Francesca Bodega, Cristina Porta, Aldo Milzani, Chiara Sironi, Isabella Dalle-Donne
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 14, p 11702 (2023)
The alveolar epithelium is covered by a non-cellular layer consisting of an aqueous hypophase topped by pulmonary surfactant, a lipo-protein mixture with surface-active properties. Exposure to cigarette smoke (CS) affects lung physiology and is linke
Externí odkaz:
https://doaj.org/article/c2ba1cb1992f410f9df6b0636eeeab7e
Publikováno v:
Antioxidants, Vol 12, Iss 5, p 1094 (2023)
Glutathione (GSH) has special antioxidant properties due to its high intracellular concentration, ubiquity, and high reactivity towards electrophiles of the sulfhydryl group of its cysteine moiety. In most diseases where oxidative stress is thought t
Externí odkaz:
https://doaj.org/article/1587d6a8914147ba885e3511abd7bb2b
Autor:
Graziano Colombo, Alessandra Altomare, Emanuela Astori, Lucia Landoni, Maria Lisa Garavaglia, Ranieri Rossi, Daniela Giustarini, Maria Chiara Lionetti, Nicoletta Gagliano, Aldo Milzani, Isabella Dalle-Donne
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 1, p 691 (2022)
Urea is the uremic toxin accumulating with the highest concentration in the plasma of chronic kidney disease (CKD) patients, not being completely cleared by dialysis. Urea accumulation is reported to exert direct and indirect side effects on the gast
Externí odkaz:
https://doaj.org/article/52291e04120e4c3bbfe4d5d3877de6d2
Autor:
Maria Lisa Garavaglia, Daniela Giustarini, Graziano Colombo, Francesco Reggiani, Silvia Finazzi, Marta Calatroni, Lucia Landoni, Nicola Marcello Portinaro, Aldo Milzani, Salvatore Badalamenti, Ranieri Rossi, Isabella Dalle-Donne
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 5, p 2853 (2022)
Thiols (sulfhydryl groups) are effective antioxidants that can preserve the correct structure of proteins, and can protect cells and tissues from damage induced by oxidative stress. Abnormal levels of thiols have been measured in the blood of patient
Externí odkaz:
https://doaj.org/article/dfd8a20c0e164faeadcb7bc4ebdfa0c1
Autor:
Elisa Roda, Sergio Barni, Aldo Milzani, Isabella Dalle-Donne, Graziano Colombo, Teresa Coccini
Publikováno v:
International Journal of Molecular Sciences, Vol 18, Iss 10, p 2115 (2017)
The potential toxic effects of silver nanoparticles (AgNPs), administered by a single intratracheal instillation (i.t), was assessed in a rat model using commercial physico-chemical characterized nanosilver. Histopathological changes, overall toxic r
Externí odkaz:
https://doaj.org/article/5a336af73d444e0c92ce80f731b4a272
Autor:
Graziano Colombo, Ranieri Rossi, Nicoletta Gagliano, Nicola Portinaro, Marco Clerici, Andrea Annibal, Daniela Giustarini, Roberto Colombo, Aldo Milzani, Isabella Dalle-Donne
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e29930 (2012)
Different studies reported the presence of oxidized (carbonylated) albumin in the extravascular pool, but not in the intravascular one of cigarette smokers. In this study we attempted to explain this apparent discrepancy exposing human serum albumin
Externí odkaz:
https://doaj.org/article/6fbb4f70a0774947b9b1fac9bb0d517d
Autor:
Diego Rubolini, Graziano Colombo, Roberto Ambrosini, Manuela Caprioli, Marco Clerici, Roberto Colombo, Isabella Dalle-Donne, Aldo Milzani, Andrea Romano, Maria Romano, Nicola Saino
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e48955 (2012)
According to life-history theory, the allocation of limiting resources to one trait has negative consequences for other traits requiring the same resource, resulting in trade-offs among life-history traits, such as reproduction and survival. In verte
Externí odkaz:
https://doaj.org/article/c87de101eb8f44b58e061dc66cb45606
Autor:
Graziano Colombo, Emanuela Astori, Lucia Landoni, Maria L. Garavaglia, Alessandra Altomare, Maria C. Lionetti, Nicoletta Gagliano, Daniela Giustarini, Ranieri Rossi, Aldo Milzani, Isabella Dalle‐Donne
Publikováno v:
Journal of applied toxicology : JATREFERENCES. 42(12)
Indoxyl sulphate (IS) is a uremic toxin accumulating in the plasma of chronic kidney disease (CKD) patients. IS accumulation induces side effects in the kidneys, bones and cardiovascular system. Most studies assessed IS effects on cell lines by testi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::527ac905a96094f5aec17b964b86a4c5
https://pubmed.ncbi.nlm.nih.gov/35854198
https://pubmed.ncbi.nlm.nih.gov/35854198