Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Isabell, Herrmann"'
Autor:
Anna Kanerva, Daniel T. Rein, Ari Ristimäki, Lotta Kangasniemi, Akseli Hemminki, Pekka Virkkunen, Minna Eriksson, Marius Porten, Gerd J. Bauerschmitz, Tanja Hakkarainen, Camilla Ribacka, Tuuli Ranki, Maija Tarkkanen, Sari Pesonen, Isabell Herrmann
Publikováno v:
Cancer Research. 68:5533-5539
It has been proposed that human tumors contain stem cells that have a central role in tumor initiation and posttreatment relapse. Putative breast cancer stem cells may reside in the CD44+CD24−/low population. Oncolytic adenoviruses are attractive f
Autor:
Devin E. Eckhoff, Michael T. Numnum, Peter Dall, Mariam A. Stoff-Khalili, Zeng B. Zhu, Alexander Stoff, J. Michael Mathis, Qiana L. Matthews, Isabell Herrmann, Angel A. Rivera, Joanne T. Douglas, David T. Curiel, Rodney P. Rocconi, Gene P. Siegal
Publikováno v:
International Journal of Cancer. 120:935-941
Conditionally replicative adenoviruses (CRAds) represent novel therapeutic agents that have been recently applied in the context of breast cancer therapy. However, deficiencies in the ability of the adenovirus to infect target tumor cells and to spec
Autor:
Paul N. Reynolds, Thomas Schöndorf, Isabell Herrmann, Daniel T. Rein, M. Breidenbach, T. Schmidt, David T. Curiel, Israel Vlodavsky, Yosef S. Haviv, Kiran N. Khan
Publikováno v:
Cancer Letters. 240:114-122
Gene therapy with adenoviral (Ad) vectors is a promising new approach in the treatment of cancer. Strategies to restrict adenoviral-mediated transgene expression are important to avoid gene transfer into normal cells. Heparanase (HPR) is overexpresse
Autor:
Mariam A, Stoff-Khalili, Angel A, Rivera, Alexander, Stoff, J, Michael Mathis, Rodney P, Rocconi, Qiana L, Matthews, Michael T, Numnum, Isabell, Herrmann, Peter, Dall, Devin E, Eckhoff, Joanne T, Douglas, Gene P, Siegal, Zeng B, Zhu, David T, Curiel
Publikováno v:
International journal of cancer. 120(4)
Conditionally replicative adenoviruses (CRAds) represent novel therapeutic agents that have been recently applied in the context of breast cancer therapy. However, deficiencies in the ability of the adenovirus to infect target tumor cells and to spec
Autor:
Isabell Herrmann, Anna Kanerva, Dirk M. Nettelbeck, David T. Curiel, Akseli Hemminki, Artur Menzel, Kilian Guse, Gerd J. Bauerschmitz, Renee A. Desmond, Masato Yamamoto, Peter Dall, Tanja Hakkarainen
Publikováno v:
Molecular therapy : the journal of the American Society of Gene Therapy. 14(2)
Conditionally replicating adenoviruses (CRAd's) feature selective replication in and killing of tumor cells. Initial clinical studies with relatively attenuated early generation agents have resulted in promising safety and efficacy data. Nevertheless
Autor:
Gerd J. Bauerschmitz, Isabell Herrmann, Dieter Niederacher, Mariam A. Stoff-Khalili, B Hanstein, Bettina Durst, Peter Dall
Publikováno v:
Cancer immunology, immunotherapy : CII. 54(1)
Purpose: The CD44 v7/8 splice variant that is frequently expressed in cervical carcinoma and rarely expressed in normal tissues displays promising properties as a target antigen for cancer immune therapy. In this study, cytotoxic T lymphocytes (CTLs)
Autor:
Minghui Wang, Ronald D. Alvarez, M. Breidenbach, Daniel T. Rein, Yuko Tsuruta, David T. Curiel, Paul N. Reynolds, Isabell Herrmann
Publikováno v:
Molecular Therapy. 9:S236
Breast cancer is a leading cause of death in the United States. Despite some advances in treatment of primary breast cancer, patients with metastatic disease still have no chance of cure and conventional treatment modalities remain palliative. Theref