Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Isabela O. Souza"'
Autor:
Luciana M.R. Antinarelli, Wallace Pacienza Lima, Jacy Gameiro, Priscila V. S. Z. Capriles, Isabela O. Souza, Elaine Soares Coimbra, Adilson David da Silva, Celso Vataru Nakamura, Elizandra Aparecida Britta
Publikováno v:
Experimental Parasitology. 195:78-86
Currently, available treatment options for leishmaniasis are limited and unsatisfactory. In a previous study, a quinoline derivative (AMQ-j), exhibited a strong effect against Leishmania amazonensis and its antileishmanial activity was preliminarily
Autor:
Isabela O. Souza, Juliana Alves dos Santos, Gilson Costa Macedo, Danielle Cristina Zimmermann-Franco, Adilson David da Silva, Nícolas de Castro Campos Pinto, Elita Scio, Bruna Esteves, Leticia Moroni Lacerda
Publikováno v:
Bioorganic & Medicinal Chemistry. 26:4898-4906
Resveratrol is a natural polyphenol found mainly on red grapes and in red wine, pointed as an important anti-inflammatory/immunomodulatory molecule. However, its bioavailability problems have limited its use encouraging the search for new alternative
Autor:
Isabela O. Souza, Rebeca Mol Lima, Nádia Rezende Barbosa Raposo, Jordana de Abreu Lazzarini, Kauana Cristina de Souza, Adilson David da Silva
Publikováno v:
Letters in Drug Design & Discovery. 14:374-379
Autor:
Luciana M.R. Antinarelli, Ayla das Chagas Almeida, Isabela O. Souza, Eveline Gomes Vasconcelos, Nícolas Glanzmann, Gabriane Nascimento Porcino, Elaine Soares Coimbra, Adilson David da Silva
Publikováno v:
Experimental Parasitology. 171:10-16
In this study, we have investigated the antileishmanial activity of ten 7-chloro-4-quinolinylhydrazone derivatives. Among the compounds tested, compounds 2a and 2j presented activity against promastigotes (IC50 values of 52.5 and 21.1 μM, respective
Autor:
Rafael M. P. Dias, Elaine Soares Coimbra, Adilson David da Silva, Isabela O. Souza, Luciana M.R. Antinarelli, Wallace Pacienza Lima, Jacy Gameiro
Publikováno v:
Chemical Biology & Drug Design. 86:704-714
The leishmanicidal activity of a series of 4-aminoquinoline (AMQ) derivatives was assayed against Leishmania amazonensis. This activity against the intracellular parasite was found stronger than for L. amazonensis promastigotes. Neither compound was
Autor:
Adilson David da Silva, Nádia Rezende Barbosa Raposo, Isabela O. Souza, Tiago Brum Braga Gomes, Rafael M. P. Dias, Hudson C. Polonini, Karla Mara Gonçalves
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 23:4506-4510
Currently, the research and development of sunscreens play an important role on the synthesis of actives that are stable in various kinds of formulations—in addition to their efficiency and broad spectrum of protection against ultraviolet radiation