Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Isabela Fraga de Andrade"'
Autor:
Isabela Fraga de Andrade, Kirby D. Johnson, Charu Mehta, Colin N. Dewey, Uttiya Basu, Emery H. Bresnick
Publikováno v:
Blood advances.
The RNA-regulatory exosome complex (EC) posttranscriptionally and cotranscriptionally processes and degrades RNAs in a context-dependent manner. Although the EC functions in diverse cell types, its contributions to stem and progenitor cell developmen
Publikováno v:
Nucleic Acids Research
Cellular differentiation requires vast remodeling of transcriptomes, and therefore machinery mediating remodeling controls differentiation. Relative to transcriptional mechanisms governing differentiation, post-transcriptional processes are less well
Publikováno v:
Nucleic Acids Research
Given the complexity of intracellular RNA ensembles and vast phenotypic remodeling intrinsic to cellular differentiation, it is instructive to consider the role of RNA regulatory machinery in controlling differentiation. Dynamic post-transcriptional
Autor:
Charu Mehta, Alexandra A. Soukup, Koichi R. Katsumura, Emery H. Bresnick, Erik A. Ranheim, Kirby D. Johnson, Isabela Fraga de Andrade, Kyle J. Hewitt
Publikováno v:
Proceedings of the National Academy of Sciences. 115
By inducing the generation and function of hematopoietic stem and progenitor cells, the master regulator of hematopoiesis GATA-2 controls the production of all blood cell types. Heterozygous GATA2 mutations cause immunodeficiency, myelodysplastic syn
Autor:
Isabela Fraga de Andrade, Emery H. Bresnick, Alexandra A. Soukup, Charu Mehta, Peng Liu, Kirby D. Johnson, Koichi R. Katsumura, Kyle J. Hewitt, Erik A. Ranheim
Publikováno v:
Blood. 134:2519-2519
The master regulator of hematopoiesis GATA2 controls generation and function of hematopoietic stem and progenitor cells, and heterozygous GATA2 mutations create a predisposition to develop immunodeficiency, myelodysplasia, and acute myeloid leukemia