Zobrazeno 1 - 10
of 192
pro vyhledávání: '"Isabel Varela‐Nieto"'
Autor:
María Domínguez-Ruiz, Silvia Murillo-Cuesta, Julio Contreras, Marta Cantero, Gema Garrido, Belén Martín-Bernardo, Elena Gómez-Rosas, Almudena Fernández, Francisco J. del Castillo, Lluís Montoliu, Isabel Varela-Nieto, Ignacio del Castillo
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-14 (2024)
Abstract Inherited hearing impairment is a remarkably heterogeneous monogenic condition, involving hundreds of genes, most of them with very small ( 90 dB SPL) that correlates with specific structural abnormalities in the cochlea. We show that Gjb2 e
Externí odkaz:
https://doaj.org/article/005dfd86e59541f7888dab03f10a4e7b
Autor:
Silvia Murillo-Cuesta, Ester Lara, Jose M. Bermúdez-Muñoz, Elena Torres-Campos, Lourdes Rodríguez-de la Rosa, Pilar López-Larrubia, Signe R. Erickson, Isabel Varela-Nieto
Publikováno v:
Translational Medicine Communications, Vol 8, Iss 1, Pp 1-19 (2023)
Abstract Background The blood-labyrinth barrier (BLB) separates the inner ear from the circulation and is critical for maintaining ionic homeostasis and limiting the entry of deleterious agents. BLB integrity is disrupted by bacterial lipopolysacchar
Externí odkaz:
https://doaj.org/article/ab02f00992ea4c529fe44ec4e8fba638
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Externí odkaz:
https://doaj.org/article/d1b7f5ba92ba4f9f8dadd3443592fe5e
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
Externí odkaz:
https://doaj.org/article/17bfd9b18c2f478393c9df3f090558a0
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
Externí odkaz:
https://doaj.org/article/d6552daf90d7424b98a940e0661696e0
Publikováno v:
Antioxidants, Vol 12, Iss 2, p 233 (2023)
Insulin-like growth factor 1 (IGF-1) is a trophic factor for the nervous system where it exerts pleiotropic effects, including the regulation of metabolic homeostasis. IGF-1 deficiency induces morphological alterations in the cochlea, apoptosis and h
Externí odkaz:
https://doaj.org/article/3fd890ac7f854efb937ef486ce023feb
Autor:
Isabel Varela-Nieto, Silvia Murillo-Cuesta, Lourdes Rodríguez-de la Rosa, María Jesús Oset-Gasque, José Marco-Contelles
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 15 (2021)
Nitrones are potent antioxidant molecules able to reduce oxidative stress by trapping reactive oxygen and nitrogen species. The antioxidant potential of nitrones has been extensively tested in multiple models of human diseases. Sensorineural hearing
Externí odkaz:
https://doaj.org/article/c4396688f88040e4bf5810aabd9e2200
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Sphingolipids are bioactive lipid components of cell membranes with important signal transduction functions in health and disease. Ceramide is the central building block for sphingolipid biosynthesis and is processed to form structurally and function
Externí odkaz:
https://doaj.org/article/340fc3070c704bceb1559f380a3d2bc6
Autor:
Silvia Murillo‐Cuesta, Adelaida M Celaya, Blanca Cervantes, Jose M Bermúdez‐Muñoz, Lourdes Rodríguez‐de la Rosa, Julio Contreras, Isabel Sánchez‐Pérez, Isabel Varela‐Nieto
Publikováno v:
Clinical and Translational Medicine, Vol 11, Iss 4, Pp n/a-n/a (2021)
Externí odkaz:
https://doaj.org/article/fc9f5b79c9594d15a1502454f34f37e5
Publikováno v:
Frontiers in Neurology, Vol 12 (2021)
Externí odkaz:
https://doaj.org/article/38ff287aa74c4ba59e2c9453b7587fdf