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of 4
pro vyhledávání: '"Isabel V. Wilson"'
Activated but functionally impaired memory Tregs are expanded in slow progressors to type 1 diabetes
Autor:
Clare Megson, Anna E. Long, Isabel V. Wilson, F. Susan Wong, Rachel J Aitken, Stephanie J. Hanna, Kathleen M Gillespie, Joanne Boldison
Publikováno v:
Diabetologia
Boldison, J, Long, A E, Aitken, R J, Wilson, I V, Hanna, S, Wong, F S & Gillespie, K M 2022, ' Activated but functionally impaired memory Tregs are expanded in slow progressors to type 1 diabetes ', Diabetologia, vol. 65, no. 2, pp. 343-355 . https://doi.org/10.1007/s00125-021-05595-0
Boldison, J, Long, A E, Aitken, R J, Wilson, I V, Hanna, S, Wong, F S & Gillespie, K M 2022, ' Activated but functionally impaired memory Tregs are expanded in slow progressors to type 1 diabetes ', Diabetologia, vol. 65, no. 2, pp. 343-355 . https://doi.org/10.1007/s00125-021-05595-0
Aims/hypothesis Slow progressors to type 1 diabetes are individuals positive for multiple pancreatic islet autoantibodies who have remained diabetes-free for at least 10 years; regulation of the autoimmune response is understudied in this group. Here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::460b8482e2433313b173be3da48524a8
http://europepmc.org/articles/PMC8741669
http://europepmc.org/articles/PMC8741669
Autor:
Stephanie J. Hanna, Claire Megson, Kathleen M Gillespie, Isabel V. Wilson, Anna E. Long, F. Susan Wong, Joanne Boldison, Rachel J Aitken
ObjectiveTo profile CD4+ regulatory T cells (Tregs) in a well-characterised cohort of slow progressors to type 1 diabetes, individuals positive for multiple islet autoantibodies who remain diabetes-free for at least 10 years.Research Design and Metho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d2899780e02b66f97150344332cddb3e
https://doi.org/10.1101/2021.01.13.21249751
https://doi.org/10.1101/2021.01.13.21249751
Autor:
Rachel J Aitken, Rebecca Wyatt, Isabel V. Wilson, Polly J. Bingley, Georgina M Williams, F. Susan Wong, Alistair J K Williams, Anna E. Long, Andrew T. Hattersley, Timothy J. McDonald, Kathleen M Gillespie
Publikováno v:
Diabetologia
Williams, G, Long, A, Wilson, I, Aitken, R, Wyatt, R, McDonald, T J, Wong, S, Hattersley, A T, Williams, A, Bingley, P & Gillespie, K 2016, ' Beta cell function and ongoing autoimmunity in long-standing, childhood onset type 1 diabetes. ', Diabetologia, vol. 59, no. 12, pp. 2722-2726 . https://doi.org/10.1007/s00125-016-4087-0
Williams, G, Long, A, Wilson, I, Aitken, R, Wyatt, R, McDonald, T J, Wong, S, Hattersley, A T, Williams, A, Bingley, P & Gillespie, K 2016, ' Beta cell function and ongoing autoimmunity in long-standing, childhood onset type 1 diabetes. ', Diabetologia, vol. 59, no. 12, pp. 2722-2726 . https://doi.org/10.1007/s00125-016-4087-0
Aims/hypothesis This study aimed to determine the frequency\ud of residual beta cell function in individuals with long-standing\ud type 1 diabetes who were recruited at diagnosis, and relate this\ud to baseline and current islet autoantibody profile.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12ca02d0ba14012ef14c1416b2cb8354
https://orca.cardiff.ac.uk/id/eprint/96318/1/WilliamsGillespieDiabetologia2016.pdf
https://orca.cardiff.ac.uk/id/eprint/96318/1/WilliamsGillespieDiabetologia2016.pdf
Autor:
Kathleen M Gillespie, Polly J. Bingley, Rachel J Aitken, Isabel V. Wilson, Alistair J K Williams
Publikováno v:
Diabetes. 63(3)
Islet autoimmunity is initiated in infancy, and primary prevention trials require children at high genetic risk to be identified before autoantibodies appear. To inform screening strategies, we evaluated risks of autoimmunity and diabetes associated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46612201190bf2f9e91f44a369e74f0e
https://pubmed.ncbi.nlm.nih.gov/24203724
https://pubmed.ncbi.nlm.nih.gov/24203724