Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Isabel Tritschler"'
Autor:
Tobias Fretwurst, Isabel Tritschler, René Rothweiler, Susanne Nahles, Brigitte Altmann, Oliver Schilling, Katja Nelson
Publikováno v:
Proteomics. Clinical applicationsREFERENCES. 16(5)
The study aim is a comparative proteome-based analysis of different autologous bone entities (alveolar bone [AB], iliac cortical [IC] bone, and iliac spongiosa [IS]) used for alveolar onlay grafting.Site-matched bone samples of AB, IC, and IS were ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6be971627dd169a34b1ae975478834a4
https://pubmed.ncbi.nlm.nih.gov/35462455
https://pubmed.ncbi.nlm.nih.gov/35462455
Autor:
Peter Schraml, Isabel Tritschler, Simon L. Goodman, Ghazaleh Tabatabai, Michaela Weller, Gabriele Maurer, Manuela Silginer, Patrick Roth, Kathy Hasenbach, Svenja Thies, Holger Moch
Transforming growth factor-β is a central mediator of the malignant phenotype of glioblastoma, the most common and malignant form of intrinsic brain tumours. Transforming growth factor-β promotes invasiveness and angiogenesis, maintains cancer cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f319f56903962af11f98560b47653f10
http://doc.rero.ch/record/304868/files/aws351.pdf
http://doc.rero.ch/record/304868/files/aws351.pdf
Autor:
Antonella Palla, Christoph Renner, Ghazaleh Tabatabai, Isabel Tritschler, Michael Weller, Hans-Georg Wirsching
Publikováno v:
Neuro-Oncology Practice. 1:178-183
Lomustine is an oral alkylating drug commonly used for brain tumor patients. Recently, the lomustine-containing PCV polychemotherapy regime (procarbazine, CCNU/lomustine, and vincristine) in combination with radiotherapy has become the standard of ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f746cb41fbc6c97568cfc54223877646
https://doi.org/10.1093/nop/npu023
https://doi.org/10.1093/nop/npu023
Publikováno v:
Neuro-Oncology. 16:382-391
BackgroundThere are emerging reports that the family of a disintegrin and metalloproteinases (ADAM) are involved in the maintenance of the malignant phenotype of glioblastomas. Notably, ADAM proteases 10 and 17 might impair the immune recognition of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa80d21397bc755db33df4fc8a4cf5b7
https://doi.org/10.1093/neuonc/not232
https://doi.org/10.1093/neuonc/not232
Autor:
Saskia Trump, Christiane A. Opitz, Bernhard Radlwimmer, Andreas von Deimling, Michael Weller, Wolfgang Wick, Theresa Schumacher, Christine L. Miller, Dieter Schrenk, Leonie Jestaedt, Irina Lehmann, Manfred Jugold, Gilles J. Guillemin, Martina Ott, Isabel Tritschler, Felix Sahm, Michael Platten, Christian Lutz, Ulrike M. Litzenburger
Publikováno v:
Nature. 478:197-203
Activation of the aryl hydrocarbon receptor (AHR) by environmental xenobiotic toxic chemicals, for instance 2,3,7,8-tetrachlorodibenzo-p-dioxin (dioxin), has been implicated in a variety of cellular processes such as embryogenesis, transformation, tu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b3681e459cc1cf2b1f80876a69406f2f
https://doi.org/10.1038/nature10491
https://doi.org/10.1038/nature10491
Autor:
Samuel N. Breit, Patrick Roth, Wolfgang Wick, Yvonne Dombrowski, Markus Junker, Isabel Tritschler, Jörg Wischhusen, Ghazaleh Tabatabai, Michael Weller, Michel Mittelbronn
Publikováno v:
Clinical Cancer Research. 16:3851-3859
Purpose: Growth and differentiation factor (GDF)-15 is a member of the transforming growth factor (TGF)-β family. GDF-15 is necessary for the maintenance of pregnancy but has also been linked to other physiologic and pathologic conditions. Experimen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10f6b753bcb2a79fb232a8af2175ffc8
https://doi.org/10.1158/1078-0432.ccr-10-0705
https://doi.org/10.1158/1078-0432.ccr-10-0705
Autor:
Wolfgang Wick, Jorma Keski-Oja, Michel Mittelbronn, Isabel Tritschler, Juha Saharinen, David Capper, Richard Meyermann, Michael Weller, Dorothee Gramatzki
Publikováno v:
International Journal of Cancer. 125:530-540
High biological activity of the transforming growth factor (TGF)-beta-Smad pathway characterizes the malignant phenotype of malignant gliomas and confers poor prognosis to glioma patients. Accordingly, TGF-beta has become a novel target for the exper
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::829445189ae5fd0aec6eac3ff0f97420
https://doi.org/10.1002/ijc.24443
https://doi.org/10.1002/ijc.24443
Autor:
G Pantazis, D Gramatzki, Isabel Tritschler, Wolfgang Wick, Ghazaleh Tabatabai, Jens Schittenhelm, Michael Schwarz, C Köhle, M. Weller
Publikováno v:
Oncogene. 28:2593-2605
The dioxin/aryl hydrocarbon receptor (AhR) is a transcription factor, which has been attributed a role in human cancerogenesis, cell cycle progression and transforming growth factor-beta (TGF-beta) signaling. As TGF-beta is an important mediator of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8606aaeacb1d213d1aee54a504000ff8
https://doi.org/10.1038/onc.2009.104
https://doi.org/10.1038/onc.2009.104
Background. The transforming growth factor (TGF)-b and vascular endothelial growth factor (VEGF) pathways have a major role in the pathogenesis of glioblastoma, notably immunosuppression, migration, and angiogenesis, but their interactions have remai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d7e9e6aca4d4b54c0231b47710a79e9
https://www.zora.uzh.ch/id/eprint/98683/
https://www.zora.uzh.ch/id/eprint/98683/
Autor:
Dorothee Gramatzki, Isabel Tritschler, Michael Weller, Larisa Espinoza, Karl Frei, Judith Johanna Schroeder, Elisabeth J. Rushing
Publikováno v:
Oncotarget
Transforming growth factor (TGF)-β is a central molecule maintaining the malignant phenotype of glioblastoma. Anti-TGF-β strategies are currently being explored in early clinical trials. Yet, there is little contemporary data on the differential ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9373671026393dae8700d700594a5d5b