Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Isabel Smith-Zubiaga"'
Autor:
Saioa López, Isabel Smith-Zubiaga, Alicia García de Galdeano, María Dolores Boyano, Oscar García, Jesús Gardeazábal, Conrado Martinez-Cadenas, Neskuts Izagirre, Concepción de la Rúa, Santos Alonso
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0134911 (2015)
We analysed the whole-genome transcriptional profile of 6 cell lines of dark melanocytes (DM) and 6 of light melanocytes (LM) at basal conditions and after ultraviolet-B (UVB) radiation at different time points to investigate the mechanisms by which
Externí odkaz:
https://doaj.org/article/d987e1877d2e4712a27a8d6a90701e70
Publikováno v:
Genomics Data, Vol 6, Iss C, Pp 195-196 (2015)
A comprehensive gene expression analysis of human melanocytes was performed assessing the transcriptional profile of dark melanocytes (DM) and light melanocytes (LM) at basal conditions and after UV-B irradiation at different time points (6, 12 and 2
Externí odkaz:
https://doaj.org/article/04b96c466e8847c6b5c96b1603973eea
Autor:
Saioa López, Oscar García, Iñaki Yurrebaso, Carlos Flores, Marialbert Acosta-Herrera, Hua Chen, Jesús Gardeazabal, Jesús María Careaga, María Dolores Boyano, Ana Sánchez, Juan Antonio Ratón-Nieto, Arrate Sevilla, Isabel Smith-Zubiaga, Alicia García de Galdeano, Conrado Martinez-Cadenas, Neskuts Izagirre, Concepción de la Rúa, Santos Alonso
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e104367 (2014)
We aimed to study the selective pressures interacting on SLC45A2 to investigate the interplay between selection and susceptibility to disease. Thus, we enrolled 500 volunteers from a geographically limited population (Basques from the North of Spain)
Externí odkaz:
https://doaj.org/article/f5b0ad1bf5f64be5829cc6a1cee2e6be
Autor:
Isabel Smith-Zubiaga, Montse Hervella, Santos Alonso, José Luis Díaz-Ramón, María Dolores Boyano, Saioa López, Neskuts Izagirre, Ana Sánchez Díez, Jesús María Careaga, Yoana Arroyo-Berdugo, Jesús Gardeazabal, Concepción de la Rúa
Publikováno v:
Human Heredity. 69:34-44
Background/Aim:TP53 is an efficient central node in a signal transduction network that responds to minimize cancer. However, over 50% of tumors show some mutation in TP53. Thus, one might argue that this single central node network lacks robustness.
Publikováno v:
Photodermatology, photoimmunologyphotomedicine. 31(3)
Summary Background/Purpose The response to the damage provoked by exposure to UV radiation is mediated by melanocytes and a network of paracrine factors produced by keratinocytes, and it varies among individuals of different geographical origin and s
Publikováno v:
Genomics Data
Genomics Data, Vol 6, Iss C, Pp 195-196 (2015)
Genomics Data, Vol 6, Iss C, Pp 195-196 (2015)
A comprehensive gene expression analysis of human melanocytes was performed assessing the transcriptional profile of dark melanocytes (DM) and light melanocytes (LM) at basal conditions and after UV-B irradiation at different time points (6, 12 and 2
Autor:
Isabel Smith-Zubiaga, J. L. Diaz-Perez, M.D. García-Vázquez, A. García de Galdeano, M L Cañavate, Jesús Gardeazabal, I. Bilbao, María Dolores Boyano, J.A. Raton
Publikováno v:
Europe PubMed Central
Elevated soluble IL-2 receptor (sIL-2R) and IL-6 serum concentrations have been reported as adverse prognostic factors in several types of cancer. In order to determine whether these factors are predictive of metastatic progression in melanoma, sIL-2
Autor:
Carlos Flores, Isabel Smith-Zubiaga, Saioa López, Maider Ibarrola-Villaba, Dolores Boyano, Concepción de la Rúa, Conrado Martinez-Cadenas, Santos Alonso, Arrate Sevilla, Jesús Gardeazabal, Neskuts Izagirre, Gloria Ribas, Maria Pino-Yanes, Oscar Garcia, Alicia García de Galdeano
Publikováno v:
Repositori Universitat Jaume I
Universitat Jaume I
Universitat Jaume I
In humans, the geographical apportionment of the coding diversity of the pigmentary locus melanocortin-1 receptor (MC1R) is, unusually, higher in Eurasians than in Africans. This atypical observation has been interpreted as the result of purifying se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::960bd69d070801befdcbcae822d53c2d
Publikováno v:
Europe PubMed Central
In this study, we analyzed interleukin-2 (IL-2) and IL-2 receptor (IL-2R) expression in murine B16F10 melanoma and studied the effect of recombinant IL-2 (rIL-2) on the proliferation of these cells. Flow cytometry analysis revealed the presence of th
Autor:
Alicia García de Galdeano, María Dolores Boyano, Antonia Alvarez, Emilio Barbera-Guillem, Isabel Smith-Zubiaga, M L Cañavate
Publikováno v:
Pathobiology. 62:186-193
Maintaining B16F10 tumor cells in stirring culture for 48 h leads to an increase in lung and liver colonizing capacity in comparison with cells in adherent culture. Parallel to the increased metastatic capacity, we have observed a decrease in the pro