Zobrazeno 1 - 10
of 113
pro vyhledávání: '"Isabel Sevilla"'
Autor:
Maria Carmen Riesco-Martinez, Jaume Capdevila, Vicente Alonso, Paula Jimenez-Fonseca, Alex Teule, Enrique Grande, Isabel Sevilla, Marta Benavent, Teresa Alonso-Gordoa, Ana Custodio, Beatriz Anton-Pascual, Jorge Hernando, Eduardo Polo, Oscar Alfredo Castillo-Trujillo, Arantza Lamas-Paz, Ana Teijo, Yolanda Rodriguez-Gil, Beatriz Soldevilla, Rocio Garcia-Carbonero
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-10 (2024)
Abstract The prognosis of patients with advanced high-grade (G3) digestive neuroendocrine neoplasms (NENs) is rather poor. The addition of immune checkpoint inhibition to platinum-based chemotherapy may improve survival. NICE-NEC (NCT03980925) is a s
Externí odkaz:
https://doaj.org/article/6981a3198f934da4bebd41d0dfe4b108
Autor:
Javier Martin-Broto, Jeronimo Martinez-Garcia, David S. Moura, Andres Redondo, Antonio Gutierrez, Antonio Lopez-Pousa, Javier Martinez-Trufero, Isabel Sevilla, Roberto Diaz-Beveridge, Maria Pilar Solis-Hernandez, Amancio Carnero, Marco Perez, David Marcilla, Jesus Garcia-Foncillas, Pablo Romero, Javier Fernandez-Jara, Daniel Lopez-Lopez, Ivan Arribas, Nadia Hindi
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-10 (2023)
Abstract Cyclin-dependent kinases 4 and 6 (CDK4/6) inhibitors demonstrated activity in terms of progression-free survival (PFS) in advanced dedifferentiated liposarcoma (DD-LPS), a sarcoma with CDK4 amplification. CDK4 overexpression is by far more c
Externí odkaz:
https://doaj.org/article/0c66d90901d244e6922dd1f9ea0a3f1f
Autor:
Jose Alejandro Pérez-Fidalgo, Eugenia Ortega, Jordi Ponce, Andres Redondo, Isabel Sevilla, Claudia Valverde, Josep Isern Verdum, Enrique de Alava, Mar Galera López, Gloria Marquina, Ana Sebio
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 15 (2023)
Uterine sarcomas are very infrequent and heterogeneous entities. Due to its rarity, pathological diagnosis, surgical management, and systemic treatment are challenging. Treatment decision process in these tumors should be taken in a multidisciplinary
Externí odkaz:
https://doaj.org/article/aaf4e864ae8949438bd7f63f170a8840
Autor:
Marta Benavent, Javier Sastre, Ignacio García Escobar, Angel Segura, Jaume Capdevila, Alberto Carmona, Isabel Sevilla, Teresa Alonso, Guillermo Crespo, Lourdes García, Neus Canal, Guillermo de la Cruz, Javier Gallego
Publikováno v:
Health and Quality of Life Outcomes, Vol 19, Iss 1, Pp 1-11 (2021)
Abstract Background and objective Patient-reported outcome measures can provide clinicians with valuable information to improve doctor-patient communication and inform clinical decision-making. The aim of this study was to evaluate the physician-perc
Externí odkaz:
https://doaj.org/article/9db66af78dec4555b4be1ebfd069bb0e
Autor:
Jaime Feliu, Rocio Garcia‐Carbonero, Jaume Capdevila, Inmaculada Guasch, Vicente Alonso‐Orduna, Carlos Lopez, Pilar Garcia‐Alfonso, Carmen Castanon, Isabel Sevilla, Laura Cerezo, Carles Conill, Begona Quintana‐Angel, Maria E. Sanchez, Ismael Ghanem, Marta Martin‐Richard, Miriam Lopez‐Gomez, Ana Leon, Monica Caro, Teresa Fernandez, Joan Maurel
Publikováno v:
Cancer Medicine, Vol 9, Iss 3, Pp 1008-1016 (2020)
Abstract Aim VITAL, a phase II single‐arm study, aimed to evaluate efficacy and safety of panitumumab addition to 5‐fluorouracil (5‐FU), mitomycin‐C (MMC) and radiotherapy (RT) in patients with localized squamous cell carcinoma of the anal ca
Externí odkaz:
https://doaj.org/article/f408da2c06104b189853b1f8992e4d37
Autor:
Javier Martínez-Trufero, Luis Miguel De Sande-González, Pablo Luna, Javier Martin-Broto, Rosa Álvarez, Gloria Marquina, Roberto Diaz-Beveridge, Andrés Poveda, Juana María Cano, Josefina Cruz-Jurado, Antonio López Pousa, María Angeles Vaz Salgado, Claudia M. Valverde-Morales, Isabel Sevilla, Jerónimo Martínez-García, Jordi Rubio-Casadevall, Ana De Juan, Juan Antonio Carrasco, David S Moura, Ibon Gurruchaga-Sotes, Antonio Gutiérrez
Publikováno v:
Cancers, Vol 13, Iss 4, p 792 (2021)
The aim of this study was to identify an easily reliable prognostic score that selects the subset of advanced soft tissue sarcoma (ASTS) patients with a higher benefit with trabectedin in terms of time to progression and overall survival. A retrospec
Externí odkaz:
https://doaj.org/article/658332108b24418cb7586c389f4b2e0a
Autor:
Beatriz Fernández-Medina, Isabel Vegas-Aguilar, José Manuel García-Almeida, Isabel Sevilla-García, Carmen Hernández-García, Francisco José Tinahones-Madueño
Publikováno v:
Endocrinología, Diabetes y Nutrición. 69:466-475
Autor:
Beatriz, Fernández-Medina, Isabel, Vegas-Aguilar, José Manuel, García-Almeida, Isabel, Sevilla-García, Carmen, Hernández-García, Francisco José, Tinahones-Madueño
Publikováno v:
Endocrinología, Diabetes y Nutrición (English ed.). 69:466-475
Patients with gastroenteropancreatic neuroendocrine tumors (GEPNET) can suffer from malnutrition. This is the first descriptive study of morfo-functional evaluation in GEPNET.To describe a morfo-functional evaluation, and to compare with reference po
Autor:
César Serrano, Rosa Álvarez, Juan Antonio Carrasco, Gloria Marquina, Jerónimo Martínez-García, Virginia Martínez-Marín, María Ángeles Sala, Ana Sebio, Isabel Sevilla, Javier Martín-Broto
Publikováno v:
Clinical and Translational Oncology.
Gastrointestinal stromal tumor (GIST) is the most common malignant neoplasm of mesenchymal origin, and a paradigmatic model for a successful rational development of targeted therapies in cancer. The introduction of tyrosine kinase inhibitors with act
Autor:
Gina Isabel Sevilla Mejía, Cesar Augusto Guevara-Cuellar, Elizabeth Parody-Rúa, Natalia Pinzón Sánchez, Maria Paula Rengifo-Mosquera
Publikováno v:
Medical Science and Discovery. 8:567-576
Objective: This study aims for three purposes: a) review the published MCDAs in oncology to identify the criteria considered valuable by the stakeholders, b) evaluate the adherence to best practice recommendations, and c) Propose a value tree, based