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pro vyhledávání: '"Isabel Schemainda"'
Autor:
Isabel Schemainda, Yuchun Chen, Cornelia Matei, Leonard B. Saltz, Alan A. Alfieri, Manickam Muruganandham, Max Hasmann, Jason A. Koutcher, George Sukenick
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 11(9)
Purpose: Attempts to selectively initiate tumor cell death through inducible apoptotic pathways are increasingly being exploited as a potential anticancer strategy. Inhibition of NAD+ synthesis by a novel agent FK866 has been recently reported to ind
Autor:
Max, Hasmann, Isabel, Schemainda
Publikováno v:
Cancer research. 63(21)
Deregulation of apoptosis, the physiological form of cell death, is closely associated with immunological diseases and cancer. Apoptosis is activated either by death receptor-driven or mitochondrial pathways, both of which may provide potential targe
Autor:
Katja, Wosikowski, Karin, Mattern, Isabel, Schemainda, Max, Hasmann, Benno, Rattel, Roland, Löser
Publikováno v:
Cancer research. 62(4)
We recently developed a class of novel antitumor agents that elicit a potent growth-inhibitory response in many tumor cells cultured in vitro. WK175, a member of this class, was chosen as a model compound that showed strong in vitro efficacy. WK175 i