Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Isabel Riba"'
Autor:
Jacqueline F. Aitken, Kerry M. Loomes, Isabel Riba-Garcia, Richard D. Unwin, Gordana Prijic, Ashley S. Phillips, Anthony R.J. Phillips, Donghai Wu, Sally D. Poppitt, Ke Ding, Perdita E. Barran, Andrew W. Dowsey, Garth J.S. Cooper
Publikováno v:
Data in Brief, Vol 10, Iss C, Pp 298-303 (2017)
Here we provide data describing the time-course of blood-glucose and fluid-intake profiles of diabetic hemizygous human-amylin (hA) transgenic mice orally treated with rutin, and matched control mice treated with water. We employed “parametric chan
Externí odkaz:
https://doaj.org/article/ee8832a3f4504ef08e14d33f38461e8b
Autor:
Antonios D. Tsiailanis, Christos M. Chatzigiannis, Christina D. Papaemmanouil, Maria V. Chatziathanasiadou, Panagiotis Chaloulos, Isabel Riba, Graham Mullard, Wiesław Wiczkowski, Apostolos Koutinas, Ioanna Mandala, Andreas G. Tzakos
Publikováno v:
Plant Foods for Human Nutrition. 77:198-205
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7383716802c81bf31a0a4f4f30174ff0
https://doi.org/10.1007/s11130-022-00962-7
https://doi.org/10.1007/s11130-022-00962-7
Autor:
Selina Mcharg, Laura Booth, Rahat Perveen, Isabel Riba Garcia, Nicole Brace, Nadhim Bayatti, Panagiotis I. Sergouniotis, Alexander M. Phillips, Anthony J. Day, Graeme C. M. Black, Simon J. Clark, Andrew W. Dowsey, Richard D. Unwin, Paul N. Bishop
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Age-related macular degeneration (AMD) is a leading cause of visual loss. It has a strong genetic basis, and common haplotypes on chromosome (Chr) 1 (CFH Y402H variant) and on Chr10 (near HTRA1/ARMS2) contribute the most risk. Little is known about t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9974eae92af93fc4602c96f95d27da5f
http://livrepository.liverpool.ac.uk/3156385/1/547377_2_merged_1650304113.pdf
http://livrepository.liverpool.ac.uk/3156385/1/547377_2_merged_1650304113.pdf
Akademický článek
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Autor:
Kerry M. Loomes, Donghai Wu, Garth J. S. Cooper, Ashley S. Phillips, Richard D. Unwin, Andrew W. Dowsey, Gordana Prijic, Anthony R. J. Phillips, Jacqueline F. Aitken, Isabel Riba-Garcia, Ke Ding, Sally D. Poppitt, Perdita E. Barran
Publikováno v:
Data in Brief, Vol 10, Iss C, Pp 298-303 (2017)
Data in Brief
Aitken, J F, Loomes, K M, Riba-Garcia, I, Unwin, R D, Prijic, G, Phillips, A S, Phillips, A R J, Wu, D, Poppitt, S D, Ding, K, Barran, P E, Dowsey, A W & Cooper, G J S 2017, ' Quantitative data describing the impact of the flavonol rutin on in-vivo blood-glucose and fluid-intake profiles, and survival of human-amylin transgenic mice ', Data in Brief, vol. 10, pp. 298-303 . https://doi.org/10.1016/j.dib.2016.11.077
Data in Brief
Aitken, J F, Loomes, K M, Riba-Garcia, I, Unwin, R D, Prijic, G, Phillips, A S, Phillips, A R J, Wu, D, Poppitt, S D, Ding, K, Barran, P E, Dowsey, A W & Cooper, G J S 2017, ' Quantitative data describing the impact of the flavonol rutin on in-vivo blood-glucose and fluid-intake profiles, and survival of human-amylin transgenic mice ', Data in Brief, vol. 10, pp. 298-303 . https://doi.org/10.1016/j.dib.2016.11.077
Here we provide data describing the time-course of blood-glucose and fluid-intake profiles of diabetic hemizygous human-amylin (hA) transgenic mice orally treated with rutin, and matched control mice treated with water. We employed “parametric chan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87457809cbfa61ef268dd4d91d968eef
Autor:
Jacqueline F. Aitken, Ke Ding, Anthony R. J. Phillips, Ashley S. Phillips, Kerry M. Loomes, Andrew W. Dowsey, Gordana Prijic, Richard D. Unwin, Garth J. S. Cooper, Donghai Wu, Isabel Riba-Garcia, Sally D. Poppitt, Perdita E. Barran
Publikováno v:
Aitken, JA, Loomes, KM, Riba Garcia, I, Unwin, R, Prijic, G, Phillips, A S, Phillips, ARJ, Wu, D, Poppitt, SD, Ding, K, Dowsey, A & Cooper, G 2017, ' Rutin suppresses human-amylin/hIAPP misfolding and oligomer formation in-vitro, and ameliorates diabetes and its impacts in human-amylin/hIAPP transgenic mice ', Biochemical and biophysical research communications, vol. 482, no. 4, pp. 625-631 . https://doi.org/10.1016/j.bbrc.2016.11.083
Aitken, J F, Loomes, K M, Riba-Garcia, I, Unwin, R D, Prijic, G, Phillips, A S, Phillips, A R J, Wu, D, Poppitt, S D, Ding, K, Barran, P E, Dowsey, A W & Cooper, G J S 2017, ' Rutin suppresses human-amylin/hIAPP misfolding and oligomer formation in-vitro, and ameliorates diabetes and its impacts in human-amylin/hIAPP transgenic mice ', Biochemical and Biophysical Research Communications, vol. 482, no. 4, pp. 625–631 . https://doi.org/10.1016/j.bbrc.2016.11.083
Aitken, J F, Loomes, K M, Riba-Garcia, I, Unwin, R D, Prijic, G, Phillips, A S, Phillips, A R J, Wu, D, Poppitt, S D, Ding, K, Barran, P E, Dowsey, A W & Cooper, G J S 2017, ' Rutin suppresses human-amylin/hIAPP misfolding and oligomer formation in-vitro, and ameliorates diabetes and its impacts in human-amylin/hIAPP transgenic mice ', Biochemical and Biophysical Research Communications, vol. 482, no. 4, pp. 625–631 . https://doi.org/10.1016/j.bbrc.2016.11.083
Pancreatic islet β-cells secrete the hormones insulin and amylin, and defective β-cell function plays a central role in the pathogenesis of type-2 diabetes (T2D). Human amylin (hA, also termed hIAPP) misfolds and forms amyloid aggregates whereas or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5aa54b3ee8b5399330f6338552d1377e
https://doi.org/10.1016/j.bbrc.2016.11.083
https://doi.org/10.1016/j.bbrc.2016.11.083
Autor:
Isabel Riba-Garcia, Anne Barton, Suzanne M M Verstappen, James Bluett, Kayode Ogungbenro, Richard D. Unwin, Thierry Wendling
Publikováno v:
Bluett, J, Riba Garcia, I, Verstappen, S, Wendling, T, Ogungbenro, K, Unwin, R & Barton, A 2019, ' Development and validation of a methotrexate adherence assay ', Annals Of Rheumatic Diseases . https://doi.org/10.1136/annrheumdis-2019-215446
BackgroundThe first-line therapy for rheumatoid arthritis (RA) is weekly oral methotrexate (MTX) at low dosages (7.5–25 mg/week). However, ~40% of patients are non-adherent which may explain why some do not respond and need to start more expensive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3380f9bb08cb904e09ed9056a978fdd
https://www.research.manchester.ac.uk/portal/en/publications/development-and-validation-of-a-methotrexate-adherence-assay(66ebd3ea-f2c8-4cef-b156-5839a4a6c8d6).html
https://www.research.manchester.ac.uk/portal/en/publications/development-and-validation-of-a-methotrexate-adherence-assay(66ebd3ea-f2c8-4cef-b156-5839a4a6c8d6).html
Autor:
Jingshu, Xu, Stefano, Patassini, Nitin, Rustogi, Isabel, Riba-Garcia, Benjamin D, Hale, Alexander M, Phillips, Henry, Waldvogel, Robert, Haines, Phil, Bradbury, Adam, Stevens, Richard L M, Faull, Andrew W, Dowsey, Garth J S, Cooper, Richard D, Unwin
Publikováno v:
Communications Biology
Alzheimer’s disease (AD) is a progressive neurodegenerative disorder that currently affects 36 million people worldwide with no effective treatment available. Development of AD follows a distinctive pattern in the brain and is poorly modelled in an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2eb427f362064486f920847d759dec50
https://pubmed.ncbi.nlm.nih.gov/30729181
https://pubmed.ncbi.nlm.nih.gov/30729181
Autor:
Garth J. S. Cooper, Adam Stevens, Richard D. Unwin, Henry J Waldvogel, Alexander M. Phillips, Robert Haines, Benjamin D. Hale, Nitin Rustogi, Phil Bradbury, Richard L.M. Faull, Isabel Riba-Garcia, Jingshu Xu, Stefano Patassini, Andrew W. Dowsey
Publikováno v:
Communications Biology, Vol 2, Iss 1, Pp 1-15 (2019)
Alzheimer’s disease (AD) is a progressive neurodegenerative disorder that currently affects 36 million people worldwide with no effective treatment available. Development of AD follows a distinctive pattern in the brain and is poorly modelled in an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::067336d9d7b212cdaaa8d65af00e5ccb
https://doi.org/10.1101/283705
https://doi.org/10.1101/283705
Publikováno v:
International Journal of Mass Spectrometry. 391:47-53
Amylin amyloid deposition is a common feature in the pancreas of type-2 diabetic (T2D) patients, and may play a role in islet beta-cell death and disease development. Type-2 diabetes is also characterised by a dysregulation of systemic copper. While
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ffad9ab24f1f5bff8da49ac253d0384
https://doi.org/10.1016/j.ijms.2015.09.001
https://doi.org/10.1016/j.ijms.2015.09.001