Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Isabel Rambaldi"'
Publikováno v:
PLoS ONE, Vol 11, Iss 12, p e0168641 (2016)
The small GTPase RhoA regulates the actin cytoskeleton to affect multiple cellular processes including endocytosis, migration and adhesion. RhoA activity is tightly regulated through several mechanisms including GDP/GTP cycling, phosphorylation, glyc
Externí odkaz:
https://doaj.org/article/bf16d57386234ef08a428ee79fc2333b
Autor:
Ricardo Sanz, Dianna E. Willis, Christopher D. Deppmann, Aaron D. Johnstone, Barbara Morquette, Marie-Eve Di Raddo, Isabel Rambaldi, Luyang Hua, Philip A. Barker, Tristan Simas, Nicolas Unsain, Mohamad R. Khazaei, Marie-Pier Girouard, Kanchana K. Gamage, Yu Yong, Valerie M. K. Verge, Alyson E. Fournier
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
eNeuro
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
eNeuro
In contrast to neurons in the CNS, damaged neurons from the peripheral nervous system (PNS) regenerate, but this process can be slow and imperfect. Successful regeneration is orchestrated by cytoskeletal reorganization at the tip of the proximal axon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48001a4ff118a0d8f5aea400513a73de
http://eneuro.org/lookup/doi/10.1523/ENEURO.0479-19.2020
http://eneuro.org/lookup/doi/10.1523/ENEURO.0479-19.2020
Autor:
Ricardo Sanz, Keith K. Murai, Martin Lévesque, Charleen Salesse, Isabel Rambaldi, Johannes Kacervosky, Alyson E. Fournier, Elizabeth Gowing, Gino B. Ferraro, Francois Beaubien, Luyang Hua, Kenn Holmbeck, Jean-François Cloutier
Publikováno v:
The Journal of Neuroscience. 38:518-529
Cell-surface molecules are dynamically regulated at the synapse to assemble and disassemble adhesive contacts that are important for synaptogenesis and for tuning synaptic transmission. Metalloproteinases dynamically regulate cellular behaviors throu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d682f5934dcc1ab8d4436c8d6c8855ac
https://doi.org/10.1523/jneurosci.0962-17.2017
https://doi.org/10.1523/jneurosci.0962-17.2017
Autor:
Marc Charabati, Nicolas Paradis-Isler, Omar de Faria Junior, Sienna S. Drake, Alyson E. Fournier, Camille A. Juźwik, Alexandre Prat, Aline Dumas, Craig S. Moore, Marc-André Lécuyer, Barbara Morquette, Stephanie Zandee, Dylan A. Galloway, Yang Zhang, Amit Bar-Or, Isabel Rambaldi, Mardja Bueno, Luc Vallières
Publikováno v:
Brain : a journal of neurology. 142(10)
Multiple sclerosis is a chronic inflammatory, demyelinating, and neurodegenerative disease affecting the brain, spinal cord and optic nerves. Neuronal damage is triggered by various harmful factors that engage diverse signalling cascades in neurons;
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40ef16cf3f6c3594fd34705967758e58
https://pubmed.ncbi.nlm.nih.gov/31412103
https://pubmed.ncbi.nlm.nih.gov/31412103
Autor:
Luc Vallières, Julia Zhang, Marc Charabati, Barbara Morquette, Camille A. Juźwik, Aline Dumas, Alexandre Prat, Dylan A. Galloway, Alyson E. Fournier, Amit Bar-Or, Sienna S. Drake, Craig S. Moore, Omar de Faria Junior, Isabel Rambaldi, Mardja Bueno, Marc-André Lécuyer
Multiple sclerosis (MS) is an autoimmune disease characterized by demyelination and neurodegeneration in the brain, spinal cord and optic nerve. Neuronal degeneration and death underlie progressive forms of MS and cognitive dysfunction. Neuronal dama
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4ff327c66d82e720b08d59181c77c30
Autor:
Masaaki Niino, Kristin Robson, Alyson E. Fournier, Amit Bar-Or, Isabel Rambaldi, Madeline Pool
Publikováno v:
Experimental Neurology. 217:371-377
The etiology of multiple sclerosis (MS) has not been fully elucidated, however evidence supports an autoimmune disease model notable for the infiltration of pro-inflammatory immune cells into sites of active demyelination and axonal injury. Previous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c167e5af8ece6a2bbdaa3b328ab2ef39
https://doi.org/10.1016/j.expneurol.2009.03.014
https://doi.org/10.1016/j.expneurol.2009.03.014
Autor:
Richard L. Maas, Angel Amores, Christof Nolte, Yi-Lin Yan, Erzsébet Nagy Kovács, Isabel Rambaldi, Maxime Bouchard, Mark Featherstone, Feng Zhang, David Grote, Sheldon Rowan, John H. Postlethwait, Mojgan Rastegar
Publikováno v:
Developmental Biology. 299(2):582-593
The antero-posterior (AP) and dorso-ventral (DV) patterning of the neural tube is controlled in part by HOX and PAX transcription factors, respectively. We have reported on a neural enhancer of Hoxd4 that directs expression in the CNS with the correc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed1316940568d16cdcd09da2c9bd7b52
Publikováno v:
Journal of Biological Chemistry. 280:10119-10127
MEIS proteins form heteromeric DNA-binding complexes with PBX monomers and PBX.HOX heterodimers. We have shown previously that transcriptional activation by PBX.HOX is augmented by either protein kinase A (PKA) or the histone deacetylase inhibitor tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ee71c8f7536f687175685b657d00f0f
https://doi.org/10.1074/jbc.m413963200
https://doi.org/10.1074/jbc.m413963200
Publikováno v:
Journal of Biological Chemistry. 279:49384-49394
The PREP, MEIS, and PBX families are mammalian members of the TALE (three amino acid loop extension) class of homeodomain-containing transcription factors. These factors have been implicated in cooperative DNA binding with the HOX class of homeoprote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae6658ea5d5a4b82b5eb2d48b2d09e7b
https://doi.org/10.1074/jbc.m406046200
https://doi.org/10.1074/jbc.m406046200
Publikováno v:
Developmental Dynamics. 227:608-614
Human WDR9 has been mapped to chromosome 21, within one of the Down syndrome (DS) critical regions. Here, we study the expression pattern of the murine Wdr9 gene and its protein product. We show that Wdr9 is broadly expressed in the mouse embryo by m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f46dee241725b46445945f1971248004
https://doi.org/10.1002/dvdy.10344
https://doi.org/10.1002/dvdy.10344