Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Isabel R. Schlaepfer"'
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Externí odkaz:
https://doaj.org/article/eeaa7dd8c8484341aafd89c216c14b74
Publikováno v:
Polymers, Vol 13, Iss 3, p 377 (2021)
Light-sensitive polymeric micelles have recently emerged as promising drug delivery systems for spatiotemporally controlled release of payload at target sites. Here, we developed diazonaphthoquinone (DNQ)-conjugated micellar nanoparticles that showed
Externí odkaz:
https://doaj.org/article/f45a289a1e5e49e48fe041718e764c61
Autor:
Molishree Joshi, Gergana E. Stoykova, Maren Salzmann-Sullivan, Monika Dzieciatkowska, Lauren N. Liebman, Gagan Deep, Isabel R. Schlaepfer
Publikováno v:
Cells, Vol 8, Iss 10, p 1115 (2019)
Prostate cancer (PCa) is the most common cancer in men, and the global burden of the disease is rising. The majority of PCa deaths are due to metastasis that are highly resistant to current hormonal treatments; this state is called castration-resista
Externí odkaz:
https://doaj.org/article/cd0d7f927ce544b38cf578d9a30aa450
Autor:
Isabel R. Schlaepfer, Leslie K. Pulawa, Luis D.M. C-B. Ferreira, David E. James, Warren H. Capell, Robert H. Eckel
Publikováno v:
Journal of Lipid Research, Vol 44, Iss 6, Pp 1174-1181 (2003)
Fatty acids inhibit insulin-mediated glucose metabolism in skeletal muscle, an effect largely attributed to defects in insulin-mediated glucose transport. Insulin-resistant mice transgenic for the overexpression of lipoprotein lipase (LPL) in skeleta
Externí odkaz:
https://doaj.org/article/c020cd405a434ea7ab6b44d161cead68
Autor:
Scott D. Cramer, Robert H. Eckel, L. Michael Glodé, S. Joseph Sirintrapun, Adela Cimic, Lina Romero, Colton T. Pac, Miguel A. Gijón, Lindsey Ulkus Rodrigues, Leah Rider, Isabel R. Schlaepfer
Supplementary figure 4: Palmitate supplementation decreases the spliced/unspliced XBP-1 ratio: LNCaP cells were treated over 48 hours with etomoxir and and with or without 100uM palmitate conjugated to albumin. Supplements Figure 4A.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::190a0d30bdab1501d7e05011054382c8
https://doi.org/10.1158/1535-7163.22502767
https://doi.org/10.1158/1535-7163.22502767
Autor:
Scott D. Cramer, Robert H. Eckel, L. Michael Glodé, S. Joseph Sirintrapun, Adela Cimic, Lina Romero, Colton T. Pac, Miguel A. Gijón, Lindsey Ulkus Rodrigues, Leah Rider, Isabel R. Schlaepfer
Supplementary figure 2: Additional human Prostate-derived patient-matched cell lines exposed to metabolic inhibitors: MTS proliferation assay of patient-matched prostate-derived benign (A) and cancer (B) cells exposed to Etomoxir and/or Orlistat for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ba09614a14b61f5d579620761b1ded9
https://doi.org/10.1158/1535-7163.22502773
https://doi.org/10.1158/1535-7163.22502773
Autor:
Scott D. Cramer, Robert H. Eckel, L. Michael Glodé, S. Joseph Sirintrapun, Adela Cimic, Lina Romero, Colton T. Pac, Miguel A. Gijón, Lindsey Ulkus Rodrigues, Leah Rider, Isabel R. Schlaepfer
Supplementary figure 3: Cleaved Caspase 3 expression in LNCaP and BPH-1 cells: Cells were treated with etomoxir over a 16 hour period and the activation of caspase 3 was examined by western blot in the cell lysates. Supplements Figure 3.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::125de67cc3c350302a1434d7de297071
https://doi.org/10.1158/1535-7163.22502770
https://doi.org/10.1158/1535-7163.22502770
Autor:
Benjamin G. Bitler, Isabel R. Schlaepfer, Kian Behbakht, Jennifer K. Richer, Zachary L. Watson, Alexandra McMellen, Tomomi M. Yamamoto, Lubna Qamar, Brandon T. Sawyer
Figure S1. HGSOC cells cultured in suspension upregulate Carnitine and Fatty Acid Metabolism. Figure S2. Confirmation of CPT1A antibody specificity. Figure S3. Oxygen consumption rate (OCR) in suspension cells and oleic acid rescue of anoikis. Figure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14bb67eb67bccae46751d5398b5ce697
https://doi.org/10.1158/1541-7786.22517206.v1
https://doi.org/10.1158/1541-7786.22517206.v1
Autor:
Scott D. Cramer, Robert H. Eckel, L. Michael Glodé, S. Joseph Sirintrapun, Adela Cimic, Lina Romero, Colton T. Pac, Miguel A. Gijón, Lindsey Ulkus Rodrigues, Leah Rider, Isabel R. Schlaepfer
Figure legends for supplementary figures and Tables. Supplementary Table 1: Primers used to analyze expression of the ER Stress-related genes and AR-related gene expression. Supplementary Table 2: Antibodies used for immunoblots and IHC.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1022e55f62747c3599e48afabcd657b9
https://doi.org/10.1158/1535-7163.22502764
https://doi.org/10.1158/1535-7163.22502764
Publikováno v:
J Raman Spectrosc
Lipid droplets are dynamic organelles that play important cellular roles. They are composed of a phospholipid membrane and a core of triglycerides and sterol esters. Fatty acids have important roles in phospholipid membrane formation, signaling, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ef141869774fbc473819fe10734ae85
https://doi.org/10.1002/jrs.6238
https://doi.org/10.1002/jrs.6238