Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Isabel R. Hendry"'
Autor:
Isabel R. Hendry, William J. Hendry
Publikováno v:
BioTechniques, Vol 20, Iss 5, Pp 812-812 (1996)
Externí odkaz:
https://doaj.org/article/c98036eb648e4cc4a96cdb56519f51ff
Publikováno v:
Cell Biology and Toxicology. 33:483-500
Treatment of Syrian hamsters on the day of birth with the prototypical endocrine disruptor and synthetic estrogen, diethylstilbestrol (DES), leads to 100% occurrence of uterine hyperplasia/dysplasia in adulthood; a large proportion of which progress
Publikováno v:
Reproductive Toxicology. 50:68-86
Neonatal treatment of hamsters with diethylstilbestrol (DES) induces uterine hyperplasia/dysplasia/neoplasia (endometrial adenocarcinoma) in adult animals. We subsequently determined that the neonatal DES exposure event directly and permanently disru
Autor:
Wendell W. Leavitt, Isabel R. Hendry, Shyamal K. Roy, William J. Hendry, Imala D. Alwis, Jeffrey V. May, Dulce M. Maroni
Publikováno v:
Reproductive Toxicology. 32:472-483
We assessed neonatal diethylstilbestrol (DES)-induced disruption at various endocrine levels in the hamster. In particular, we used organ transplantation into the hamster cheek pouch to determine whether abnormalities observed in the post-pubertal ov
Autor:
Kevin L. Obholz, John Suter, Liliane Ndjountche, Isabel R. Hendry, John S. Davis, Bo R. Rueda, James K. Pru
Publikováno v:
Biology of Reproduction. 64:1481-1486
Interferon gamma (IFNγ) has been implicated as a mediator of luteal steroidogenesis and cell fate. IFNγ-initiated signaling events, although implied by studies in cell lines, have yet to be described in primary luteal cells. The objective of these
Autor:
John S. Davis, Isabel R. Hendry, Fredrick Stormshak, William J. Hendry, Bo R. Rueda, Ov D. Slayden
Publikováno v:
Biology of Reproduction. 62:269-276
We tested the hypothesis that progesterone (P4) acts at a local level to inhibit luteal apoptosis. Initial experiments employed aminoglutethimide, a P450 cholesterol side-chain cleavage inhibitor, to inhibit steroid synthesis. Cultured bovine luteal
Publikováno v:
Endocrine. 12:315-321
Insulin-like growth factor-I (IGF-I) is an important differentiation and survival factor for granulosa cells. The purpose of this study was to test the hypothesis that IGF-I promotes survival of porcine granulosa cells by signaling through the phosph
Publikováno v:
Biology of Reproduction. 60:1087-1092
Caspase-3, a vertebrate homologue of the protein encoded by the Caenorhabditis elegans cell death gene, ced-3, induces apoptosis when overexpressed in eukaryotic cells. Since apoptosis occurs during corpus luteum (CL) regression in many species, incl
Publikováno v:
Journal of Chromatography B: Biomedical Sciences and Applications. 570:235-242
A high-performance liquid chromatographic method for the measurement of bumetanide in plasma and urine is described. Following precipitation of proteins with acetonitrile, bumetanide was extracted from plasma or urine on a 1-ml bonded-phase C18 colum
Publikováno v:
Endocrinology. 143(11)
Fas ligand (FasL) is implicated as a mediator of luteolysis. However, a gap exists in our understanding of the Fas-mediated signaling mechanisms that are involved in either the loss of progesterone production or the structural regression of the corpu