Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Isabel Muñoz-Barroso"'
Autor:
Ruth Henríquez, Isabel Muñoz-Barroso
Publikováno v:
Heliyon, Vol 10, Iss 15, Pp e34927- (2024)
To overcome the limitations of conventional vaccines, new platforms for vaccine design have emerged such as those based on viral vectors and virus-like particles (VLPs). Viral vector vaccines are highly efficient and the onset of protection is quick.
Externí odkaz:
https://doaj.org/article/434e8a1b9b8f4cde8bb93c584b038339
Publikováno v:
Archives of Virology. 165:2165-2176
The PI3K/Akt signalling pathway is a crucial signalling cascade that regulates transcription, protein translation, cell growth, proliferation, cell survival, and metabolism. During viral infection, viruses exploit a variety of cellular pathways, incl
Publikováno v:
Virus Research. 191:138-142
Although it is well documented that the initial attachment receptors for Newcastle Disease Virus (NDV) and Respiratory Syncytial Virus (RSV) are sialic acid-containing molecules and glycosaminoglycans respectively, the exact nature of the receptors f
Publikováno v:
Biochimica et Biophysica Acta. Biomembranes
Most paramyxoviruses enter the cell by direct fusion of the viral envelope with the plasma membrane. Our previous studies have shown the colocalization of Newcastle Disease Virus (NDV) with the early endosome marker EEA1 and the inhibition of NDV fus
Autor:
Galina G. Zhadan, Isabel Muñoz Barroso, Eduard Y. Kostetsky, Sara Cuadrado-Castano, Valery L. Shnyrov, Enrique Villar, Javier Gómez, Irene Sánchez Morán
Publikováno v:
International Journal of Biological Macromolecules. 61:390-395
The thermal stability of the matrix protein (M protein) of Newcastle disease virus (NDV) has been investigated using high-sensitivity differential scanning calorimetry (DSC) at pH 7.4. The thermal folding/unfolding of M protein at this pH value is a
Publikováno v:
Glycoconjugate Journal
Receptor recognition and binding is the first step in the viral cycle. It has been established that Newcastle Disease Virus (NDV) interacts with sialylated molecules such as gangliosides and glycoproteins at the cell surface. Nevertheless, the specif
Autor:
Isabel Muñoz-Barroso, Enrique Villar, Juan José Martín, Javier Holguera, Lorena Sánchez-Felipe
Publikováno v:
Biochimica et Biophysica Acta. Biomembranes
Lipid rafts are membrane microdomains enriched in cholesterol, sphingolipids, and glycolipids that have been implicated in many biological processes. Since cholesterol is known to play a key role in the entry of some other viruses, we investigated th
Publikováno v:
Journal of Virology. 84:1066-1075
The entry of enveloped viruses into host cells is preceded by membrane fusion, which in paramyxoviruses is triggered by the fusion (F) protein. Refolding of the F protein from a metastable conformation to a highly stable postfusion form is critical f
Autor:
Anna M. Bianchi, Luigi Anastasia, Isabel Muñoz-Barroso, Enrique Villar, Nadia Papini, Eugenio Monti, Javier Holguera, Francesca D'Avila, Cristina Tringali, Bruno Venerando, Guido Tettamanti
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 1780:504-512
The paramyxovirus Newcastle Disease Virus (NDV) binds to sialic acid-containing glycoconjugates, sialoglycoproteins and sialoglycolipids (gangliosides) of host cell plasma membrane through its hemagglutinin-neuraminidase (sialidase) HN glycoprotein.
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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The entry into cells of Newcastle disease virus (NDV), a prototype member of the paramyxoviruses, is believed to occur by direct fusion at the plasma membrane through a pH-independent mechanism. In addition, NDV may enter host cells by an endocytic p