Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Isabel Meister"'
Autor:
Serge Rudaz, Elena Tobolkina, Víctor González-Ruiz, Isabel Meister, Miguel De Figueiredo, Davy Guillarme, Julien Boccard
Publikováno v:
CHIMIA, Vol 76, Iss 1-2 (2022)
Untargeted metabolomics is now widely recognized as a useful tool for exploring metabolic changes taking place in biological systems under different conditions. In this article, we aim to provide a short overview of the liquid-phase separation method
Externí odkaz:
https://doaj.org/article/63375c2c951b4ade96f8a668cec83d11
Autor:
Tatjana Vujić, Domitille Schvartz, Izadora Liranço Furlani, Isabel Meister, Víctor González-Ruiz, Serge Rudaz, Jean-Charles Sanchez
Publikováno v:
Cells, Vol 11, Iss 23, p 3926 (2022)
Morphine, a commonly used antinociceptive drug in hospitals, is known to cross the blood-brain barrier (BBB) by first passing through brain endothelial cells. Despite its pain-relieving effect, morphine also has detrimental effects, such as the poten
Externí odkaz:
https://doaj.org/article/a583a59ba5c84e6ba1f669626246371a
Autor:
Ipputa Tada, Hiroshi Tsugawa, Isabel Meister, Pei Zhang, Rie Shu, Riho Katsumi, Craig E. Wheelock, Masanori Arita, Romanas Chaleckis
Publikováno v:
Metabolites, Vol 9, Iss 11, p 251 (2019)
Accurate metabolite identification remains one of the primary challenges in a metabolomics study. A reliable chemical spectral library increases the confidence in annotation, and the availability of raw and annotated data in public databases facilita
Externí odkaz:
https://doaj.org/article/9487100499464ceaa5f29dc4b11c867c
Autor:
Pei Zhang, Manish Arora, Romanas Chaleckis, Tomohiko Isobe, Mohit Jain, Isabel Meister, Erik Melén, Matthew Perzanowski, Federico Torta, Markus R. Wenk, Craig E. Wheelock
Publikováno v:
Metabolites, Vol 9, Iss 6, p 106 (2019)
The attempt to describe complex diseases by solely genetic determination has not been successful. There is increasing recognition that the development of disease is often a consequence of interactions between multiple genetic and environmental factor
Externí odkaz:
https://doaj.org/article/13213780fb2e4371a655182ca4b2e0c2
Autor:
Rodi Abdalkader, Pei Zhang, Ken-ichiro Kamei, Craig E. Wheelock, Isabel Meister, Romanas Chaleckis
Publikováno v:
Analytical Sciences. 37:1049-1052
Metabolome analysis in micro physiological models is a challenge due to the low volume of cell culture medium (CCM). Here, we report a LC-MS-based untargeted metabolomics protocol for the detection of hepatocyte extracellular metabolites from micro-s
Autor:
Isabel Meister, Jana Kovac, Urs Duthaler, Peter Odermatt, Jörg Huwyler, Fiona Vanobberghen, Somphou Sayasone, Jennifer Keiser
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 10, Iss 5, p e0004700 (2016)
BACKGROUND:Praziquantel (PZQ) is the treatment of choice for infections with the liver fluke Opisthorchis viverrini, a major health problem in Southeast Asia. However, pharmacokinetic (PK) studies investigating the disposition of PZQ enantiomers (R-
Externí odkaz:
https://doaj.org/article/2e1857a9e67f4c9f9fd56154ea0b7316
Akademický článek
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Autor:
Ville M. Koistinen, Pei Zhang, Robert O. Wright, Jonathan W. Martin, Mengna Huang, Kalliroi Sdougkou, Craig E. Wheelock, Hiroshi Tsugawa, Christopher Carlsten, Stefano Papazian, Kati Hanhineva, Douglas I. Walker, Tomohiko Isobe, Tracey J. Woodruff, Isabel Meister, Romanas Chaleckis, Hongyu Xie, Stephen M. Rappaport
Publikováno v:
Environmental science & technology letters, vol 8, iss 10
Environmental Science & Technology Letters
Environmental Science & Technology Letters
The concept of the exposome was introduced over 15 years ago to reflect the important role that the environment exerts on health and disease. While originally viewed as a call-to-arms to develop more comprehensive exposure assessment methods applicab
Autor:
Christine Falcoz, Serge Guzy, Jana Kovač, Isabel Meister, Jean Coulibaly, Somphou Sayasone, David Wesche, Yu-Wei Lin, Jennifer Keiser
Publikováno v:
Journal of pharmacokinetics and pharmacodynamics. 49(3)
Racemic praziquantel (PZQ) is the standard treatment for schistosomiasis and liver fluke infections (opisthorchiasis and clonorchiasis). The development of an optimal pediatric formulation and dose selection would benefit from a population pharmacoki
Autor:
Romanas Chaleckis, Åsa M. Wheelock, Isabel Meister, Craig E. Wheelock, Pei Zhang, Takashi Izumi, C. Magnus Sköld, Anirban Sinha
Publikováno v:
Analytical chemistry, 93(12), 5248-5258. American Chemical Society
Analytical Chemistry
Analytical Chemistry
Urine is a noninvasive biofluid that is rich in polar metabolites and well suited for metabolomic epidemiology. However, because of individual variability in health and hydration status, the physiological concentration of urine can differ >15-fold, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ee41067360f213b49d19b1b6ae25061
https://pure.amc.nl/en/publications/highprecision-automated-workflow-for-urinary-untargeted-metabolomic-epidemiology(dcbf2952-02e5-4bc3-8328-d362b3ad65db).html
https://pure.amc.nl/en/publications/highprecision-automated-workflow-for-urinary-untargeted-metabolomic-epidemiology(dcbf2952-02e5-4bc3-8328-d362b3ad65db).html