Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Isabel Martinez-Garay"'
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
Neural precursors generate neurons in the embryonic brain and in restricted niches of the adult brain in a process called neurogenesis. The precise control of cell proliferation and differentiation in time and space required for neurogenesis depends
Externí odkaz:
https://doaj.org/article/5b4d46ef6cd44776bda746fb7d05a6f2
Autor:
Hayley Dingsdale, Xinsheng Nan, Samantha M. Garay, Annett Mueller, Lorna A. Sumption, Pedro Chacón-Fernández, Isabel Martinez-Garay, Cedric Ghevaert, Yves-Alain Barde, Rosalind M. John
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Brain-derived neurotrophic factor (BDNF) plays crucial roles in brain function. Numerous studies report alterations in BDNF levels in human serum in various neurological conditions, including mood disorders such as depression. However, littl
Externí odkaz:
https://doaj.org/article/83413d4173a3405ca4356581ac93840d
Autor:
Isabel Martinez-Garay
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
During development of the cerebral cortex, different types of neurons migrate from distinct origins to create the different cortical layers and settle within them. Along their way, migrating neurons use cell adhesion molecules on their surface to int
Externí odkaz:
https://doaj.org/article/4db551e9cddc4906ad0e8800c811bbcb
Autor:
Christine P Diggle, Isabel Martinez-Garay, Zoltan Molnar, Martin H Brinkworth, Ed White, Ewan Fowler, Ruth Hughes, Bruce E Hayward, Ian M Carr, Christopher M Watson, Laura Crinnion, Aruna Asipu, Ben Woodman, P Louise Coletta, Alexander F Markham, T Neil Dear, David T Bonthron, Michelle Peckham, Ewan E Morrison, Eamonn Sheridan
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0174264 (2017)
Tubulin alpha 8 (Tuba8) is the most divergent member of the highly conserved alpha tubulin family, and uniquely lacks two key post-translational modification sites. It is abundantly expressed in testis and muscle, with lower levels in the brain. We p
Externí odkaz:
https://doaj.org/article/018e0d0b0c5f4a439d4efb23ef2dfb63
Publikováno v:
eNeuro
The regulation of neuronal soma size is essential for appropriate brain circuit function and its dysregulation is associated with several neurodevelopmental disorders. A defect in the dendritic growth and elaboration of motor neocortical pyramidal ne
Autor:
Rosalind M. John, Isabel Martinez-Garay, Hayley Dingsdale, Samantha M. Garay, Cedric Ghevaert, Xinsheng Nan, Annett Mueller, Pedro Chacón-Fernández, Lorna Sumption, Yves-Alain Barde
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-12 (2021)
Translational Psychiatry
Translational Psychiatry
Funder: European Union’s Horizon 2020 Research and Innovation Programme under the Marie Skłodowska-Curie Grant Agreement 663830
Funder: Welsh Government’s Sêr Cymru programme
Funder: NHS Blood and Transplant
Brain-derived neurotr
Funder: Welsh Government’s Sêr Cymru programme
Funder: NHS Blood and Transplant
Brain-derived neurotr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56274fa6c293c7886ecafad495528f9e
https://orca.cardiff.ac.uk/id/eprint/138916/1/s41398-020-01176-8.pdf
https://orca.cardiff.ac.uk/id/eprint/138916/1/s41398-020-01176-8.pdf
Autor:
Natalia, Galindo-Riera, Sylvia Adriana, Newbold, Monika, Sledziowska, Cristina, Llinares-Benadero, Jessica, Griffiths, Erik, Mire, Isabel, Martinez-Garay
Publikováno v:
eNeuro
Mutations in the X-linked cell adhesion protein PCDH19 lead to seizures, cognitive impairment, and other behavioral comorbidities when present in a mosaic pattern. Neither the molecular mechanisms underpinning this disorder nor the function of PCDH19
Autor:
Sylvia Adriana Newbold, Isabel Martinez-Garay, Jessica Griffiths, Monika Sledziowska, Natalia Galindo-Riera, Erik Mire
Mutations in the X-linked cell adhesion protein PCDH19 lead to seizures, cognitive impairment and other behavioral comorbidities when present in a mosaic pattern. Neither the molecular mechanisms underpinning this disorder, nor the function of PCDH19
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a5d63292a43bb9d71b40e7411f42856f
https://doi.org/10.1101/2020.08.27.271239
https://doi.org/10.1101/2020.08.27.271239
Autor:
Jessica Griffiths, Natalia Galindo-Riera, Monika Sledziowska, Erik Mire, Cristina Llinares-Benadero, Sylvia Adriana Newbold, Isabel Martinez-Garay
Publikováno v:
eneuro. 8:ENEURO.0510-20.2021
Mutations in the X-linked cell adhesion protein PCDH19 lead to seizures, cognitive impairment and other behavioral comorbidities when present in a mosaic pattern. Neither the molecular mechanisms underpinning this disorder, nor the function of PCDH19
Autor:
Tomasz Schneider, Luiz G. Guidi, Antonio Velayos-Baeza, Daniel Lyngholm, Zoltán Molnár, Melissa A. G. Bailey, Isabel Martinez-Garay, Timothy Donnison, Zoe G. Holloway, Simon J. B. Butt, Anthony P. Monaco
Publikováno v:
Brain Structure & Function
Developmental dyslexia is a common disorder with a strong genetic component, but the underlying molecular mechanisms are still unknown. Several candidate dyslexia-susceptibility genes, including KIAA0319, DYX1C1, and DCDC2, have been identified in hu