Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Isabel M. Mol"'
Autor:
Jan Kroon, Maaike Schilperoort, Wietse In het Panhuis, Rosa van den Berg, Lotte van Doeselaar, Cristy R.C. Verzijl, Nikki van Trigt, Isabel M. Mol, Hetty H.C.M. Sips, Jose K. van den Heuvel, Lisa L. Koorneef, Ronald J. van der Sluis, Anna Fenzl, Florian W. Kiefer, Sabine Vettorazzi, Jan P. Tuckermann, Nienke R. Biermasz, Onno C. Meijer, Patrick C.N. Rensen, Sander Kooijman
Publikováno v:
Molecular Metabolism, Vol 47, Iss , Pp 101179- (2021)
Objective: Brown adipose tissue (BAT) displays a strong circadian rhythm in metabolic activity, but it is unclear how this rhythm is regulated. As circulating levels of corticosterone coincide with the rhythm of triglyceride-derived fatty acid (FA) u
Externí odkaz:
https://doaj.org/article/1ca61bd60fff4069a39d7542195ccab5
Autor:
Rosa van den Berg, Sander Kooijman, Raymond Noordam, Ashna Ramkisoensing, Gustavo Abreu-Vieira, Lauren L. Tambyrajah, Wieneke Dijk, Philip Ruppert, Isabel M. Mol, Barbara Kramar, Rosanna Caputo, Laura Sardón Puig, Evelien M. de Ruiter, Jan Kroon, Menno Hoekstra, Ronald J. van der Sluis, Onno C. Meijer, Ko Willems van Dijk, Linda W.M. van Kerkhof, Constantinos Christodoulides, Fredrik Karpe, Zachary Gerhart-Hines, Sander Kersten, Johanna H. Meijer, Claudia P. Coomans, Diana van Heemst, Nienke R. Biermasz, Patrick C.N. Rensen
Publikováno v:
Cell Reports, Vol 22, Iss 13, Pp 3521-3533 (2018)
Summary: Many favorable metabolic effects have been attributed to thermogenic activity of brown adipose tissue (BAT). Yet, time of day has rarely been considered in this field of research. Here, we show that a diurnal rhythm in BAT activity regulates
Externí odkaz:
https://doaj.org/article/6c5163a02d86464f999e3824a47cbd0f
Autor:
Lisa T. C. M. van Weert, Jacobus C. Buurstede, Hetty C. M. Sips, Isabel M. Mol, Tanvi Puri, Ruth Damsteegt, Benno Roozendaal, R. Angela Sarabdjitsingh, Onno C. Meijer
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 7, p 1575 (2019)
Mineralocorticoid receptor (MR)-mediated signaling in the brain has been suggested as a protective factor in the development of psychopathology, in particular mood disorders. We recently identified genomic loci at which either MR or the closely relat
Externí odkaz:
https://doaj.org/article/fc6dbfc030b448e9b2528a9dbff1c1a5
Autor:
Eline N. Kuipers, Andrea D. van Dam, Ntsiki M. Held, Isabel M. Mol, Riekelt H. Houtkooper, Patrick C.N. Rensen, Mariëtte R. Boon
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 6, p 1786 (2018)
Obesity and dyslipidemia are major risk factors for the development of cardiovascular diseases (CVD). Quercetin, a natural flavonoid, lowers plasma triglycerides (TG) in human intervention studies, and its intake is associated with lower CVD risk. Th
Externí odkaz:
https://doaj.org/article/1e960c3f6f0e425192bc720c089e8f51
Autor:
Janna A. van Diepen, Jimmy F.P. Berbée, Geerte Hoeke, Thirumala D. Kanneganti, Patrick C.N. Rensen, Tom Houben, Anneke Hijmans, Kathrin Thiem, Mariëtte R. Boon, Isabel M. Mol, Rinke Stienstra, Esther Lutgens, Margien G.S. Boels, Cees J. Tack, Ronit Shiri-Sverdlov, Enchen Zhou, Mihai G. Netea, Johan Bussink
Publikováno v:
Diabetes & vascular disease research. SAGE Publications Ltd
Diabetes and Vascular Disease Research. SAGE PUBLICATIONS LTD
Diabetes and Vascular Disease Research
Diabetes & Vascular Disease Research, 17, 1
Diabetes & Vascular Disease Research, 17(1), 1-12. SAGE Publications Ltd
Diabetes & Vascular Disease Research
Diabetes and Vascular Disease Research 17 (2020) 1
Diabetes and Vascular Disease Research, 17(1), 1-12
Diabetes & Vascular Disease Research, 17
Diabetes and Vascular Disease Research. SAGE PUBLICATIONS LTD
Diabetes and Vascular Disease Research
Diabetes & Vascular Disease Research, 17, 1
Diabetes & Vascular Disease Research, 17(1), 1-12. SAGE Publications Ltd
Diabetes & Vascular Disease Research
Diabetes and Vascular Disease Research 17 (2020) 1
Diabetes and Vascular Disease Research, 17(1), 1-12
Diabetes & Vascular Disease Research, 17
Background: C-type lectin receptors, including Dectin-2, are pattern recognition receptors on monocytes and macrophages that mainly recognize sugars and sugar-like structures present on fungi. Activation of C-type lectin receptors induces downstream
Autor:
Wietse In het Panhuis, Isabel M. Mol, Maaike Schilperoort, Rosa van den Berg, José K. van den Heuvel, Cristy R.C. Verzijl, Onno C. Meijer, Nienke R. Biermasz, Lisa L. Koorneef, Sabine Vettorazzi, Jan Tuckermann, Nikki van Trigt, Ronald J. van der Sluis, Patrick C.N. Rensen, Jan Kroon, Hetty C M Sips, Florian W. Kiefer, Sander Kooijman, Lotte van Doeselaar, Anna Fenzl
Publikováno v:
MOLECULAR METABOLISM, 47. ELSEVIER
Molecular Metabolism
Molecular Metabolism, Vol 47, Iss, Pp 101179-(2021)
Molecular Metabolism
Molecular Metabolism, Vol 47, Iss, Pp 101179-(2021)
Objective Brown adipose tissue (BAT) displays a strong circadian rhythm in metabolic activity, but it is unclear how this rhythm is regulated. As circulating levels of corticosterone coincide with the rhythm of triglyceride-derived fatty acid (FA) up
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e7e537823eb01e9efb304237c64cdd0
https://doi.org/10.1016/j.molmet.2021.101179
https://doi.org/10.1016/j.molmet.2021.101179
Autor:
Rinke Stienstra, Cor Jacobs, Geerte Hoeke, Isabel M. Mol, Esther Lutgens, Kathrin Thiem, Cees J. Tack, Janna A. van Diepen, Enchen Zhou, Susan M. van den Berg, Johan Bussink, Maria Mouktaroudi, Mihai G. Netea, Thirumala D. Kanneganti, Anneke Hijmans, Jimmy F.P. Berbée, Patrick C.N. Rensen
Publikováno v:
Scientific Reports, 9
Scientific reports, 9(1):4337. Nature Publishing Group
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Scientific Reports, 9(1)
Scientific Reports
Scientific Reports, 9. NATURE PUBLISHING GROUP
Scientific Reports 9 (2019) 1
Scientific reports, 9(1):4337. Nature Publishing Group
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Scientific Reports, 9(1)
Scientific Reports
Scientific Reports, 9. NATURE PUBLISHING GROUP
Scientific Reports 9 (2019) 1
Inflammatory reactions activated by pattern recognition receptors (PRRs) on the membrane of innate immune cells play an important role in atherosclerosis. Whether the PRRs of the C-type lectin receptor (CLR) family including Dectin-2 may be involved
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1a2b74c6d848a35624d9d3d14576238
https://hdl.handle.net/2066/202010
https://hdl.handle.net/2066/202010
Autor:
Mathias V. Schmidt, Jan Tuckermann, Benno Roozendaal, Jacobus C. Buurstede, Wilbert Zwart, Lisa T. C. M. van Weert, Sabine Vettorazzi, Stefan Prekovic, Isabel M. Mol, Hetty C M Sips, Onno C. Meijer, Jakob Hartmann, R. Angela Sarabdjitsingh
Publikováno v:
Journal of Neuroendocrinology, 31(8). WILEY
Journal of Neuroendocrinology, 31, 8
Journal of Neuroendocrinology, 31
Journal of Neuroendocrinology
Journal of Neuroendocrinology, 31, 8
Journal of Neuroendocrinology, 31
Journal of Neuroendocrinology
Brain mineralocorticoid receptors (MRs) and glucocorticoid receptors (GRs) respond to the same glucocorticoid hormones but can have differential effects on cellular function. Several lines of evidence suggest that MR‐specific target genes must exis
Autor:
Benno Roozendaal, Jacobus C. Buurstede, Lisa T C M van Weert, Ruth Damsteegt, Tanvi Puri, Onno C. Meijer, R. Angela Sarabdjitsingh, Isabel M. Mol, Hetty C M Sips
Publikováno v:
International Journal of Molecular Sciences, 20
International Journal of Molecular Sciences
International Journal of Molecular Sciences, 20, 7
Volume 20
Issue 7
International Journal of Molecular Sciences, Vol 20, Iss 7, p 1575 (2019)
International Journal of Molecular Sciences, 20(7). MDPI
International Journal of Molecular Sciences
International Journal of Molecular Sciences, 20, 7
Volume 20
Issue 7
International Journal of Molecular Sciences, Vol 20, Iss 7, p 1575 (2019)
International Journal of Molecular Sciences, 20(7). MDPI
Mineralocorticoid receptor (MR)-mediated signaling in the brain has been suggested as a protective factor in the development of psychopathology, in particular mood disorders. We recently identified genomic loci at which either MR or the closely relat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06db43a266275e5ae44abf3d35a98dbc
http://hdl.handle.net/2066/203582
http://hdl.handle.net/2066/203582
Autor:
Lisa T C M van Weert, Aldo Grefhorst, José K. van den Heuvel, Ahmed Mahfouz, Jenny A. Visser, Boudewijn P. F. Lelieveldt, Nicole A. Datson, Marcel J. T. Reinders, Hetty C M Sips, Onno C. Meijer, Isabel M. Mol
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 113(10), 2738-2743. National Academy of Sciences
Proceedings of the National Academy of Sciences, 113(10), 2738-2743. NATL ACAD SCIENCES
Proceedings of the National Academy of Sciences of the U.S.A., 113(10), 2738-2743. National Academy of Sciences
Proceedings of the National Academy of Sciences, 113(10), 2738-2743. NATL ACAD SCIENCES
Proceedings of the National Academy of Sciences of the U.S.A., 113(10), 2738-2743. National Academy of Sciences
Steroid receptors are pleiotropic transcription factors that coordinate adaptation to different physiological states. An important target organ is the brain, but even though their effects are well studied in specific regions, brain-wide steroid recep