Zobrazeno 1 - 10
of 437
pro vyhledávání: '"Isabel Loza"'
Autor:
Francesca Intranuovo, Leonardo Brunetti, Pietro DelRe, Giuseppe Felice Mangiatordi, Angela Stefanachi, Antonio Laghezza, Mauro Niso, Francesco Leonetti, Fulvio Loiodice, Alessia Ligresti, Magdalena Kostrzewa, Jose Brea, Maria Isabel Loza, Eddy Sotelo, Michele Saviano, Nicola Antonio Colabufo, Chiara Riganti, Carmen Abate, Marialessandra Contino
Publikováno v:
Journal of Medicinal Chemistry. 66:235-250
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c666b4e83426dc75645a7d6456be23db
https://doi.org/10.1021/acs.jmedchem.2c01084
https://doi.org/10.1021/acs.jmedchem.2c01084
Akademický článek
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Autor:
Luis Filipe Costa-Machado, Esther Garcia-Dominguez, Rebecca L. McIntyre, Jose Luis Lopez-Aceituno, Álvaro Ballesteros-Gonzalez, Andrea Tapia-Gonzalez, David Fabregat-Safont, Tobias Eisenberg, Jesús Gomez, Adrian Plaza, Aranzazu Sierra-Ramirez, Manuel Perez, David Villanueva-Bermejo, Tiziana Fornari, María Isabel Loza, Gonzalo Herradon, Sebastian J. Hofer, Christoph Magnes, Frank Madeo, Janet S. Duerr, Oscar J. Pozo, Maximo-Ibo Galindo, Isabel del Pino, Riekelt H. Houtkooper, Diego Megias, Jose Viña, Mari Carmen Gomez-Cabrera, Pablo J. Fernandez-Marcos
Publikováno v:
Nature Communications. 14
Reversible and sub-lethal stresses to the mitochondria elicit a program of compensatory responses that ultimately improve mitochondrial function, a conserved anti-aging mechanism termed mitohormesis. Here, we show that harmol, a member of the beta-ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::17b9c50dead5ed741feca7c78e2ca644
https://doi.org/10.1038/s41467-023-38410-y
https://doi.org/10.1038/s41467-023-38410-y
Autor:
Maris-Johanna Tahk, Tõnis Laasfeld, Elo Meriste, Jose Brea, Maria Isabel Loza, Maria Majellaro, Marialessandra Contino, Eddy Sotelo, Ago Rinken
Publikováno v:
Frontiers in Molecular Biosciences. 10
Dopamine receptors are G-protein-coupled receptors that are connected to severe neurological disorders. The development of new ligands targeting these receptors enables gaining a deeper insight into the receptor functioning, including binding mechani
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::54fabb7894fc6f05eef2404a97279a8f
https://doi.org/10.3389/fmolb.2023.1119157
https://doi.org/10.3389/fmolb.2023.1119157
Autor:
Flavia Montaño-Centellas, Alfredo F. Fuentes, Leslie Cayola, Manuel J. Macía, Gabriel Arellano, M. Isabel Loza, Beatriz Nieto-Ariza, J. Sebastián Tello
AimThe climate variability hypothesis proposes that species subjected to wide variation in climatic conditions will evolve wider niches, resulting in larger distributions. We test this hypothesis in tropical plants across a broad elevational gradient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::200016cf6618fedbd108c74494bd2f21
https://doi.org/10.1101/2023.02.21.529430
https://doi.org/10.1101/2023.02.21.529430
Autor:
Eric March-Vila, Giacomo Ferretti, Emma Terricabras, Inés Ardao, José Manuel Brea, María José Varela, Álvaro Arana, Juan Andrés Rubiolo, Ferran Sanz, María Isabel Loza, Laura Sánchez, Héctor Alonso, Manuel Pastor
There is a widely recognized need to reduce human activity's impact on the environment. Many industries of the leather and textile sector (LTI), being aware of producing a significant amount of residues (Keßler et al. 2021; Liu et al. 2021), are ado
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::563e90960466debbdf0c72b119079801
http://hdl.handle.net/10230/56138
http://hdl.handle.net/10230/56138
Autor:
Shubaash Anthiya, Süleyman Can Öztürk, Hamdullah Yanik, Ece Tavukcuoglu, Adem Şahin, Dhrubajyoti Datta, Klaus Charisse, David Moreira Álvarez, María Isabel Loza, Alfonso Calvo, Einar Sulheim, Simon Loevenich, Geir Klinkenberg, Ruth Schmid, Muthiah Manoharan, Güneş Esendağlı, Maria Jose Alonso
K-RAS is a highly relevant oncogene that is mutated in approximately 90% of pancreatic cancers and 20–25% of lung adenocarcinomas. The aim of this work was to develop a new anti-KRAS siRNA therapeutic strategy through the engineering of functionali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27d546c8f9a778fb6999cb14a0ee3108
https://hdl.handle.net/10347/30619
https://hdl.handle.net/10347/30619
Autor:
Francesca, Intranuovo, Leonardo, Brunetti, Pietro, DelRe, Giuseppe Felice, Mangiatordi, Angela, Stefanachi, Antonio, Laghezza, Mauro, Niso, Francesco, Leonetti, Fulvio, Loiodice, Alessia, Ligresti, Magdalena, Kostrzewa, Jose, Brea, Maria Isabel, Loza, Eddy, Sotelo, Michele, Saviano, Nicola Antonio, Colabufo, Chiara, Riganti, Carmen, Abate, Marialessandra, Contino
Publikováno v:
Journal of medicinal chemistry.
Cannabinoid type 2 receptor (CB2R), belonging to the endocannabinoid system, is overexpressed in pathologies characterized by inflammation, and its activation counteracts inflammatory states. Fatty acid amide hydrolase (FAAH) is an enzyme responsible
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a17cd73abaaa431a4bd4eccf4714d7c7
https://pubmed.ncbi.nlm.nih.gov/36542836
https://pubmed.ncbi.nlm.nih.gov/36542836
Autor:
Maria Isabel Loza, Julija Hmeljak, Chas Bountra, James E. Audia, Sohini Chowdhury, Shannon Weiman, Kalpana Merchant, Maria-Jesus Blanco
Publikováno v:
Disease Models & Mechanisms. 15
Brain diseases are a major cause of death and disability worldwide and contribute significantly to years of potential life lost. Although there have been considerable advances in biological mechanisms associated with brain disorders as well as drug d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d83f94e87253575f08a6f7e8da690f0
https://doi.org/10.1242/dmm.049755
https://doi.org/10.1242/dmm.049755
Autor:
Karina Garcia-Cabrera, Norma Salinas, Leslie Cayola, Amy E. Zanne, Alexander G. Linan, Beatriz Nieto-Ariza, J. Sebastián Tello, Sebastián González-Caro, William Farfan-Rios, Gabriel Arellano, M. Isabel Loza, Yadvinder Malhi, Alfredo F. Fuentes, Manuel J. Macía, Jonathan Myers, Stephen A. Smith, Christine E. Edwards, Miles R. Silman
Publikováno v:
New Phytologist. 232:2506-2519
Recent studies have demonstrated that ecological processes that shape community structure and dynamics change along environmental gradients. However, much less is known about how the emergence of the gradients themselves shape the evolution of specie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f591834f5a43462e3c0a50948bf5159
https://doi.org/10.1111/nph.17674
https://doi.org/10.1111/nph.17674