Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Isabel Lopez-Marin"'
Autor:
M. Josefa Bello, M. Eva Alonso, Jesús Vaquero, Juan A. Rey, Jose M. de Campos, Jesus Lomas, Alberto Isla, Isabel Lopez-Marin, Cinthia Amiñoso, Dolores Arjona, Victor Martinez-Glez
Publikováno v:
Genes, Chromosomes and Cancer. 42:314-319
The role of the NF2 gene in the development of meningiomas has recently been documented; inactivating mutations plus allelic loss at 22q, the site of this gene (at 22q12), have been identified in both sporadic and neurofibromatosis type 2-associated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::568aac7d25b96cfd04dd76b10e682884
https://doi.org/10.1002/gcc.20141
https://doi.org/10.1002/gcc.20141
Autor:
Alberto Isla, Dolores Arjona, M. Eva Alonso, Pilar Gonzalez-Gomez, Jose M. de Campos, Cinthia Amiñoso, Cacilda Casartelli, Jose L. Sarasa, Jesús Vaquero, Juan A. Rey, Manuel Gutierrez, Isabel Lopez-Marin, Nilson Praia Anselmo, M.Elena Kusak, Luis Lassaletta, M. Josefa Bello
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 554:23-32
O6-methylguanine-DNA methyltransferase (MGMT) plays a major role in repairing DNA damage from alkylating agents. By removing alkyl groups from the O6-position in guanine, MGMT can prevent G:C to A:T transition mutations, a type of variation frequentl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df4abfa293a83a152c5136283c7bce66
https://doi.org/10.1016/j.mrfmmm.2004.02.011
https://doi.org/10.1016/j.mrfmmm.2004.02.011
Autor:
Pilar Gonzalez-Gomez, Cinthia Amiñoso, Dolores Arjona, Jesus Lomas, Isabel Lopez-Marin, M. Josefa Bello, Jose M. de Campos, Jose L. Sarasa, Jesús Vaquero, Juan A. Rey, Manuel Gutierrez, M.Elena Kusak, M. Eva Alonso, Alberto Isla
Publikováno v:
Acta Neuropathologica. 108:413-421
The purpose of this research was to examine the DNA methylation profile of meningiomas. Accordingly, we examined the DNA methylation status of ten tumor-related genes (RB1, p16 INK4a , p73, MGMT, ER, DAPK, TIMP-3, p14 ARF , THBS1, and Caspase-8) in 9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2827780b8ccdd09231826cbd7756da74
https://doi.org/10.1007/s00401-004-0911-6
https://doi.org/10.1007/s00401-004-0911-6
Autor:
J.L Sarasa, M E Alonso, Isabel Lopez-Marin, Nilson Praia Anselmo, Dolores Arjona, M.J. Bello, Cacilda Casartelli, Pilar Gonzalez-Gomez, Cinthia Amiñoso, Jesus Lomas, Juan A. Rey, Manuel Gutierrez
Publikováno v:
European Journal of Cancer. 39:1478-1485
Aberrant hypermethylation occurs in tumour cell CpG islands and is an important pathway for the repression of gene transcription in cancers. We investigated aberrant hypermethylation of 11 genes by methylation-specific polymerase chain reaction (PCR)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e77773b6d888ba5f3f659581bce418da
https://doi.org/10.1016/s0959-8049(03)00312-5
https://doi.org/10.1016/s0959-8049(03)00312-5
Autor:
Dolores Arjona, Alberto Isla, Jose M. de Campos, Jesús Vaquero, Juan A. Rey, Manuel Gutierrez, M. Eva Alonso, Isabel Lopez-Marin, Pilar Gonzalez-Gomez, Cinthia Amiñoso, Jose L. Sarasa, M. Josefa Bello
Publikováno v:
Oncology Reports.
Loss of 1p heterozygosity is one of the most characteristic events in oligodendrogliomas. Several genes located in this region have been previously studied to find the target gene implicated in the development of this tumor without success. Patched-2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::163f827773af4dba9145d1da6d348c94
https://doi.org/10.3892/or.13.3.539
https://doi.org/10.3892/or.13.3.539
Autor:
Jesus, Lomas, M Josefa, Bello, Dolores, Arjona, M Eva, Alonso, Victor, Martinez-Glez, Isabel, Lopez-Marin, Cinthia, Amiñoso, Jose M, de Campos, Alberto, Isla, Jesus, Vaquero, Juan A, Rey
Publikováno v:
Genes, chromosomescancer. 42(3)
The role of the NF2 gene in the development of meningiomas has recently been documented; inactivating mutations plus allelic loss at 22q, the site of this gene (at 22q12), have been identified in both sporadic and neurofibromatosis type 2-associated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e547cf428cc6bf84976add6eae9b28c8
https://pubmed.ncbi.nlm.nih.gov/15609345
https://pubmed.ncbi.nlm.nih.gov/15609345
Autor:
Dolores Arjona, M. Eva Alonso, M. Josefa Bello, Pilar Gonzalez-Gomez, Cinthia Amiñoso, Juan A. Rey, M Mar Inda, Jose L. Sarasa, Isabel Lopez-Marin, Jose M. de Campos, Javier S. Castresana
Publikováno v:
Oncology Reports.
Aberrant methylation of promoter CpG islands in human genes is an alternative genetic inactivation mechanism that contributes to the development of human tumors. Nevertheless, few studies have analyzed methylation in medulloblastomas. We determined t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df1a5f2835574b42e1ecd6c50c47e1ef
https://doi.org/10.3892/or.12.3.663
https://doi.org/10.3892/or.12.3.663
Autor:
Pilar, Gonzalez-Gomez, M Josefa, Bello, M Mar, Inda, M Eva, Alonso, Dolores, Arjona, Cinthia, Amiñoso, Isabel, Lopez-Marin, Jose M, de Campos, Jose L, Sarasa, Javier S, Castresana, Juan A, Rey
Publikováno v:
Oncology reports. 12(3)
Aberrant methylation of promoter CpG islands in human genes is an alternative genetic inactivation mechanism that contributes to the development of human tumors. Nevertheless, few studies have analyzed methylation in medulloblastomas. We determined t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::991ba02f84649c1a081697c3c699e816
https://pubmed.ncbi.nlm.nih.gov/15289853
https://pubmed.ncbi.nlm.nih.gov/15289853
Autor:
M. Eva Alonso, Jose L. Sarasa, Jesús Vaquero, Juan A. Rey, Manuel Gutierrez, Jose M. de Campos, M. Josefa Bello, Alberto Isla, Dolores Arjona, Jesus Lomas, Isabel Lopez-Marin, Pilar Gonzalez-Gomez, Cinthia Amiñoso
Publikováno v:
Cancer genetics and cytogenetics. 148(2)
Deletions at 1p are frequent in meningioma and represent a genetic marker associated with the genesis of atypical WHO grade II forms. Previous mutational analysis of TP73, a structurally and functionally TP53 homologous gene located at 1p36.33, faile
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::928de895b64d4e5da6e38231a31c7a4e
https://pubmed.ncbi.nlm.nih.gov/14734228
https://pubmed.ncbi.nlm.nih.gov/14734228
Autor:
Pilar Gonzalez-Gomez, Cinthia Amiñoso, Jose M. de Campos, M. Eva Alonso, Juan A. Rey, Alberto Isla, Manuel Gutierrez, Isabel Lopez-Marin, M. Josefa Bello
Publikováno v:
International Journal of Molecular Medicine.
The aberrant methylation of the CpG island promoter regions acquired by tumor cells is one mechanism for loss of gene function. The high methylation rate for RB1 and death-associated protein-kinase gene (DAP-kinase) (60 and 90%, respectively) previou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a6d150c865ed55058c8c938131f9c349
https://doi.org/10.3892/ijmm.13.1.93
https://doi.org/10.3892/ijmm.13.1.93