Zobrazeno 1 - 10
of 95
pro vyhledávání: '"Isabel Leroux"'
Autor:
Hannah Siwe, Annelies Aerssens, Mieke V. Flour, Silke Ternest, Leen Van Simaey, Duncan Verstraeten, Alain F. Kalmar, Isabel Leroux-Roels, Philip Meuleman, Piet Cools
Publikováno v:
Heliyon, Vol 10, Iss 17, Pp e37281- (2024)
Background: Despite the many guidelines for reprocessing of medical instruments, challenges persist such as microbial resistance to biocides, corrosive effects on materials, and time-consuming reprocessing procedures. Ultraviolet (UV) C light-emittin
Externí odkaz:
https://doaj.org/article/2bce87fb6224402a911698ab18844f45
Autor:
Valentino D’Onofrio, Sharon Porrez, Bart Jacobs, Azhar Alhatemi, Fien De Boever, Gwenn Waerlop, Els Michels, Francesca Vanni, Alessandro Manenti, Geert Leroux-Roels, Peter Paul Platenburg, Luuk Hilgers, Isabel Leroux-Roels
Publikováno v:
Vaccines, Vol 12, Iss 9, p 1036 (2024)
Seasonal influenza vaccine effectiveness is low. Carbohydrate fatty acid monosulphate ester (CMS), a new oil-in-water adjuvant, has proven potency in animal models with suggested capacity for dose-sparing. The objective was to evaluate safety and imm
Externí odkaz:
https://doaj.org/article/5ca3304e712c41af9db534402afe1e73
Autor:
Hannelore Hamerlinck, Annelies Aerssens, Jerina Boelens, Andrea Dehaene, Michael McMahon, Anne-Sophie Messiaen, Stien Vandendriessche, Anja Velghe, Isabel Leroux-Roels, Bruno Verhasselt
Publikováno v:
Antimicrobial Resistance and Infection Control, Vol 12, Iss 1, Pp 1-13 (2023)
Abstract Background Accumulating evidence shows a role of the hospital wastewater system in the spread of multidrug-resistant organisms, such as carbapenemase producing Enterobacterales (CPE). Several sequential outbreaks of CPE on the geriatric ward
Externí odkaz:
https://doaj.org/article/d6c19842c24c4f13b44e9aa1caf29791
Autor:
Sien De Koster, Basil Britto Xavier, Christine Lammens, Natascha Perales Selva, Stefanie van Kleef-van Koeveringe, Samuel Coenen, Youri Glupczynski, Isabel Leroux-Roels, Wouter Dhaeze, Christian J P A Hoebe, Jeroen Dewulf, Arjan Stegeman, Marjolein Kluytmans-Van den Bergh, Jan Kluytmans, Herman Goossens, i-4-1-Health Study Group
Publikováno v:
PLoS ONE, Vol 19, Iss 2, p e0298096 (2024)
BackgroundColistin serves as the last line of defense against multidrug resistant Gram-negative bacterial infections in both human and veterinary medicine. This study aimed to investigate the occurrence and spread of colistin-resistant Enterobacteral
Externí odkaz:
https://doaj.org/article/9ffceac568464b9bba72111133d6a947
Autor:
Elien Vandoorn, Wojciech Stadejek, Isabel Leroux-Roels, Geert Leroux-Roels, Anna Parys, Kristien Van Reeth
Publikováno v:
Emerging Infectious Diseases, Vol 29, Iss 1, Pp 98-109 (2023)
Influenza A viruses (IAVs) of subtype H3 that infect humans are antigenically divergent from those of birds, horses, and swine. Human immunity against these viruses might be limited, implying potential pandemic risk. To determine human risk, we selec
Externí odkaz:
https://doaj.org/article/75dc792e1cc34b58a2b3c555786e72dd
Autor:
Gwenn Waerlop, Yorick Janssens, Bart Jacobs, Franziska Jarczowski, André Diessner, Geert Leroux-Roels, Victor Klimyuk, Isabel Leroux-Roels, Frank Thieme
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
The development of an efficacious vaccine against norovirus is of paramount importance given its potential to reduce the global burden of norovirus-associated morbidity and mortality. Here, we report a detailed immunological analysis of a phase I, do
Externí odkaz:
https://doaj.org/article/f7335b481858407fbb8da1fd8c01564b
Autor:
Stephanie Pepin, Jean-François Nicolas, Henryk Szymanski, Isabel Leroux-Roels, Thomas Schaum, Marc Bonten, Giancarlo Icardi, Anju Shrestha, Cynthia Tabar, The QHD00011 study team
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 17, Iss 12, Pp 5475-5486 (2021)
A quadrivalent high-dose inactivated influenza vaccine (IIV4-HD) is licensed for adults ≥65 y of age based on immunogenicity and efficacy studies. However, IIV4-HD has not been evaluated in adults aged 60–64 y. This study compared immunogenicity
Externí odkaz:
https://doaj.org/article/00843d9ce111450f920635f631acd873
Autor:
Isabel Leroux-Roels, Cathy Maes, Jasper Joye, Bart Jacobs, Franziska Jarczowski, André Diessner, Yorick Janssens, Gwenn Waerlop, Kirsi Tamminen, Suvi Heinimäki, Vesna Blazevic, Geert Leroux-Roels, Victor Klimyuk, Hiroshi Adachi, Kazuyuki Hiruta, Frank Thieme
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Noroviruses (NoV) are the leading cause of epidemic acute gastroenteritis in humans worldwide and a safe and effective vaccine is needed. Here, a phase I, double-blind, placebo-controlled clinical trial was performed in 60 healthy adults, 18 to 40 ye
Externí odkaz:
https://doaj.org/article/bb6df2d5e1e744729c3ccc75dafbda24
Autor:
Yorick Janssens, Jasper Joye, Gwenn Waerlop, Frédéric Clement, Geert Leroux-Roels, Isabel Leroux-Roels
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Influenza vaccines remain the most effective tools to prevent flu and its complications. Trivalent or quadrivalent inactivated influenza vaccines primarily elicit antibodies towards haemagglutinin and neuraminidase. These vaccines fail to induce high
Externí odkaz:
https://doaj.org/article/262c4faa458545149a31be97fec53a78
Autor:
Isabel Leroux-Roels, Geert Leroux-Roels, Georgi Shukarev, Hanneke Schuitemaker, Conor Cahill, Richard de Rooij, Martin Struijs, Hester van Zeeburg, Jeanne-Marie Jacquet
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 17, Iss 5, Pp 1366-1373 (2021)
This first-in-human study (NCT03032588), conducted in Belgium, evaluated a new inactivated poliovirus vaccines (IPV) candidate based on Sabin poliovirus strains grown on the high-yield PER.C6® cell line. Healthy adults (N = 32) were randomized (1:1)
Externí odkaz:
https://doaj.org/article/8d9a181505c642feaf0a71a258804c4c